Meiosis

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Unit 3: Cell Division

Left Side

Unit Page

Flow Map – Cell Cycle

Brace Map – Meiosis

Pg Right Side

48 Table of Contents

50 C.N. – The Cell Cycle

52 C.N. – Meiosis

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53

Pg

49

Meiosis

Unit 3:

Cell Division

Chapter 11-4

Learning Goals

1. Describe the overall process of meiosis.

2. Define homologous chromosomes and explain diploid and haploid.

3. Explain crossing over, its importance, and during which step it occurs.

4. Describe the two types of gamete formation and how fertilization occurs.

Meiosis

A process of cell division that creates gamete cells , or nonidentical cells with half the number of chromosomes

The gametes from a male and a female combine in sexual reproduction to make a new individual

Homologous Chromosomes

Each cell has 2 sets of chromosomes

Homologous Chromosomes = a pair of chromosomes that have the same genes at the same locations

 1 came from mom

 1 came from dad

Homologous chromosomes

From mom

From dad

Chromosome Number

Diploid (2n) : cells that have 2 sets of homologous chromosomes (2n)

 Human body cells are diploid ( 46 chromosomes or 23 pairs)

Haploid (n) : cells that have 1 set of chromosomes (n)

 sex cells ( gametes ) are haploid

 human haploid cells (egg & sperm) have 23 chromosomes total

1) A bug has a haploid number n=5. What is the diploid number (2n)?

2) A crocodile has a diploid number 2n=50.

What is the haploid number (n)?

meiosis

Diploid

2n meiosis

Haploid gamete n n

Haploid gamete

Human Female Karyotype

Human Male Karyotype

Down Syndrome Female

Trisomy

Meiosis Overview

A type of cell division specific to sexual reproduction (two parent cells)

Cells (diploid) divide twice resulting in 4 daughter cells (haploid)

Each cell has half the number of chromosomes as the original cell

Each new cell is genetically different

Steps of Meiosis

Interphase

DNA is copied before the start of Meiosis I.

This makes 2 identical sister chromatids

They have the same genes at the same locations.

Homologous chromosomes vs. sister chromatids

From mom

From dad

Meiosis 1

Four steps:

Prophase 1

Metaphase 1

Anaphase 1

Telophase 1

Prophase 1

The homologous pairs of chromosomes come together and line up side by side . (tetrad = 4)

Crossing-over

Homologous chromosomes can

Cross-over and exchange a portion of the chromosome

(DNA) at random

Crossing-over is very important in meiosis because it creates genetic variation (new combinations of genes), which makes us all different.

This is why you do not look exactly like your siblings.

Crossing over happens randomly.

However, some genes are linked, or close together on the chromosome, meaning they are more likely to be inherited together.

Red hair

Freckles

Chromosome 16

After crossing-over, the homologous chromosomes separate & the cells divide

Meiosis II

Four steps:

Prophase 2

Metaphase 2

Anaphase 2

Telophase 2

Sister chromatids separate & the cells divide.

Result is 4 genetically different haploid daughter cells

Principal of Independent

Assortment

Genes for different traits can segregate (separate) independently during the formation of gametes.

 Independent assortment and crossing-over account for the many genetic variations observed in plants, animals, and other organisms.

Assume there was only one crossover in a man’s sperm and one crossover in a woman’s egg, they have the possibility of producing

4,951,760,200,000,000,000,000,000,000 genetically different children

Gamete Formation

Gametes = Sex Cells ( eggs & sperm )

 Spermatogenesis:

In males meiosis occurs in the testes

 produces 4 sperm

23

23

23 23

Spermatogenesis

 Oogenisis:

In females meiosis occurs in the ovaries

 produces only 1 egg and 3 polar bodies

Polar Bodies

Egg

23

Oogenesis

Fertilization : the fusion of haploid sex cells

23 23

Zygote

46

First cell of a new organism

Only one sperm and one egg come together

The first sperm to reach the egg will be the one to fertilize it.

Comparing Mitosis & Meiosis

Mitosis results in the production of 2 genetically identical diploid cells.

Meiosis produces 4 genetically different haploid cells .

Learning Goals

1. Describe the overall process of meiosis.

2. Define homologous chromosomes and explain diploid and haploid.

3. Explain crossing over, its importance, and during which step it occurs.

4. Describe the two types of gamete formation and how fertilization occurs.

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