DNA Technology: Bioethics, Gene Therapy, Transgenic Organisms and Cloning SB2 f Examine the use of DNA technology in forensics, medicine, and agriculture. Activator •Answer the following question on your index card: •Does the government have a right to control scientific research if it will eventually save lives? Bioethics The idea of whether an a scientific act is morally responsible. Your mother has been diagnosed with Alzheimer’s disease. She is okay now but you know that eventually she will forget everyone and everything. Her doctor offers her the opportunity to participate in an experimental process. Do you… • A. Take the risk and participate in the process knowing that it may or may not work • B. Say no and cherish the time that you have Gene Therapy • Gene therapy • is the fixing abnormal genes that cause disease by replacing then with normal genes. • Possible cures for: • • • • • • diabetes cardiovascular disease cystic fibrosis Alzheimer's Parkinson’s and many other diseases is possible. If scientist can replace damaged organs, should it matter where they come from? Genetic Engineering • The manipulation or modification of genes. Photo of a mouse growing a "human ear" Genetically modified organisms are called transgenic organisms. TRANSGENIC ANIMALS Mice – used to study human immune system Chickens – more resistant to infections Cows – increase milk supply and leaner meat Goats, sheep and pigs – produce human proteins in their milk Transgenic Goat Human DNA in a Goat Cell This goat contains a human gene that codes for a blood clotting agent. . The blood clotting agent can be harvested in the goat’s milk. This could help heal people with hemophilia. What if you had a twin that didn’t come from your mother? Cloning • What is it? • Cloning is the creation of an organism that is an exact genetic copy http://learn.genetics.utah.ed of another. This u/content/tech/cloning/whati means that every scloning/twinning.html single bit of DNA is the same between the two! • This process is nonsexual and done in a laboratory situation. Dolly: A Mammal Clone • In 1997, Dolly was the first mammal to be cloned. She was cloned by Scottish scientists, Ian Wilmut, at the Roslin Institute. If you could make a copy of anything in the world what would it be? THE MISSION • Mr. Medder’s is feeling extremely generous today and has decided to give the Science department the money to allow all biology students the opportunity to clone anything in the world they would like. • The catch is you only have 15 mins to do it. You must create your clone and explain why you chose to clone that particular item. • If you can convince Ms. Wimbush that your clone is meaningful she will allow you to keep it. If you fail your original and the clone will be confiscated and never returned to you. Good Luck, your mission begins now! Bioethics The idea of whether an a scientific act is morally responsible. •Does the government have a right to tell you that you can not save your child’s life by saving their cord blood? • Summarizer: Take an index card and tell me your opinion on the issue.