NAJRAN UNIVERSITY
College of Medicine
Microbiology &Immunology Course
Lecture No. 1
By
Dr. Ahmed Morad Asaad
Professor of Microbiology
Course specification
Institution
College/Department
Najran University
College of
Medicine/Microbiology
department
A. Course identification and general information
Course title and code
Credit hours
General Microbiology &
Immunology (MIC-4 244)
5(4+1) for 12 weeks
Program
Faculty member
responsible for
the course
Level/year
Pre-requisites
Co-requisites
Location
Bachelor of Medicine
Dr Ahmed Morad Asaad
(Coordinator)
Dr Ahmed Morad Asaad
(Theoretical)
Dr Moawia Albadri (Practical)
4th level/2nd year
--Main Campus
General objectives:
By the end of this course, the students will be able to:
1- Understand the structure, physiology, metabolism and
genetics of medically important bacteria, viruses and
fungi.
2- Acquire the basic skills of microbiological laboratory
standard techniques for diagnosis of microbial
infections.
3- Develop an understanding of sterilization, disinfection,
antiseptics and antimicrobial chemotherapy.
4- Define the different parasitology terms and
differentiate between the followings: ectoparasites
versus
endoparasites,
definitive
hosts
versus
intermediate hosts, facultative parasites versus obligate
parasites, and mechanical vectors versus biological
vectors.
5- Classify medically-important parasitic infections as a
protozoal or helminth disease.
6- Differentiate between human infection and human
disease.
7- Understand the basic components of the immune
system including innate and acquired immune response.
8- Gain knowledge about humoral and cell-mediated
immunity.
9- Understand the mechanisms of protective immunity
against microbial infections focusing on the antigens,
antibodies, complement, cells and their receptors,
cytokines and other molecules involved in the immune
response.
10- Realize and utilize the immunological methods for
laboratory diagnosis of human diseases.
List of topics
History of microbiology
Bacterial structure
Bacterial physiology and
metabolism
Bacterial genetics
Antimicrobial agents
Host parasite relationship
Antigens and immunogens
Innate immunity
Acquired immunity & cells of
the immune response
Credit hours
1
2
2
3
2
2
1
1
2
Cell mediated immunity
Cytokines
Major histocompatibility
complex
Humoral immunity
Complement system
Protective immunity to microbes
Immunoprophylaxis
Hypersensitivity reactions
General properties of viruses
Bacteriophages
Pathogenesis of viral infections
Laboratory methods for
diagnosis of viral infections
2
2
1
1
2
1
1
2
2
2
1
1
Antiviral drugs
General properties of fungi
Antifungal drugs
Introduction to medical parasitology
Classification of medically important
parasitic infections
Immunity to parasitic infections
Antiparasitic drugs
Laboratory safety measures &
Specimen collection and transport
Microscopic examination of bacteria
(Unstained & stained smears)
Isolation of bacteria (Culture media &
cultivation procedure)
Identification of isolated bacteria
Antibiotic sensitivity tests
1
1
1
1
1
1
1
1
2
1
1
1
Sterilization and disinfection
Agglutination assays
Precipitation assays
Complement fixation test,
neutralization assays, radio immune
assay, monoclonal antibodies
(technique and application)
ELSA & Immunofluorescence
(technique and application)
Laboratory techniques for diagnosis of
viral infection
Techniques in mycology lab
Diagnostic procedures in parasitology
lab
1
1
1
1
1
1
1
1
3- Course components (total contact hours per
semester):
Lecture
40
Tutorial
4
Laboratory Practical
11
11
5- Teaching methodology
Theoretical
Practical
 Lectures: Data show – Group
discussion
 Tutorials
 Audio-visual learning
 Students working in the lab
 Practical notebook
 Audio-visual learning
Other
--
Course assessment
Continuous
Mid-term Exams
Final Term Exam
assessment
20%
60%
20%
 2 MCQs Quizes  Mid-term Exams  One Exam
(10 minutes
(MCQs + short
(MCQs + short
each): 5%
account)
account):
 Students
40%T+20%P
attendance: 10%
 Practical
notebook: 5%
Schedule of assessment tasks
Assess
ment
Assessment task
Week due
1
2
3
4
5
1st Quiz
Mid-term Exam
2nd Quiz
Practical notebook
Attendance
6
Final term Exam
Lecture No 10
5th week
Lecture No 30
11th week
The whole 11
weeks
12th week
Proportion
of final
assessment
2.5%
20%
2.5%
5%
10%
60%
Students support
Availability of teaching staff
for consultations and advice.
Learning resources
(a)- Required texts
1. Lectures handout
2. Practical notebook
(b)Recommended
books and
reference
material
Medical Microbiology & Immunology.
Examination and Board review Warren
Levinson, and
Jawetz E. 6th edition.
Bailey and Scott’s Diagnostic
Microbiology. Baron and Finegold. Latest
Edition.
Manual of Clinical Microbiology. Murray
PR, et al. ASM Press. Latest Edition.
Cellular and Molecular Immunology. Abul K
Abas, 6th edition
Medical Immunology. Daniel PS, et al.
Appelton & Lange Co. CA, USA. Latest
edition.
Clinical Immunology and Serology: A
Laboratory Perspective. Stevens C, CSH
press. Latest edition.
(c)Electronic
resources
1. E-Learning (education by fun): Video
tapes (audio-visual)
2. www.WHO.com
3. www.CDC.com
4. www.ASM.com