from Pons —> through Middle peduncles from Medulla —> through Inferior peduncles CERULEO-cerebellar PONTO-cerebellar Preprogram fine motor movements – UE Regulates activities from cortex to cerebellum Nuclei: Pontine Nuclei (pons) Nuclei: Locus coeruleus (midbrain) Course: Middle peduncles Course: Superior peduncles Neurotransmitter: Glutamate Neurotransmitter: Noradrenalin RETICULO-cerebellar Update motor info by integrating visual and vestibular circuit RAPHE-cerebellar Modulates neuronal activities throughout brainstem and in the cerebellum. Nuclei: Reticular formation (pons and medulla) Nuclei: Raphe nuclei (pons and medulla) Course: Middle and Inferior peduncles Course: Middle and inferior peduncles Neurotransmitter: Enkephalin Neurotransmitter: Serotonin OLIVO-cerebellar HYPOTHALAMO-cerebellar Mediates spinal reflexes and cortical impulses Function obscured for now Nuclei: Olivary nuclei (medulla) Nuclei in hypothalamus Course: Superior peduncles Course: Inferior peduncle Neurotransmitter: Histamine Neurotransmitter: Aspartate, Corticotropin 2. Fiber: mossy - all of them except—> climbing - OLIVOcerebellar General Rules 1. Peduncles: from Midbrain —> through Superior peduncles 3. All tracts end up in cerebellar cortex and nuclei SPINOCEREBELLAR TRACTS - ASCENDING TRACTS TRACTS ORIGIN COURSE Ends Function DECUSSATION NEUROTRANSMITTER Dorsal/Posterior Spinocerebellar Tract (PSCT) L3 Lamina VIINucleus of Clarke *Inferior Cerebellar Peduncle Cerebellar: 1. cortex 2. nuclei (collateral axons) Unconscious proprioceptive input from GTO and muscle spindles (tone and length) of LE NO Glutamate (+) Cuneocerebellar (analogous tract to PSCT) C8-C1 Cuneate fasciculus *synapsing at the Accessory (lateral) cuneate nucleus at the medulla * Inferior Cerebellar Peduncle “ Unconscious proprioceptive input from GTO and muscle spindles of UE NO “ Ventral/Anterior Spinocerebellar Tract (ASCT) S2 Lamina VII Intermediate Zone *travels ipsilateral and contralateral *enters the cerebellum via Superior Cerebellar Peduncle. BILATERAL PROJECTIONS to each cerebellar hemispheres “ Unconscious proprioceptive input from GTO- LEs At the spinal level “ Rostral Spinocerebellar Tract (analogous tract to ASCT) C8-C4 Lamina VII Intermediate Zone *Inferior Cerebellar Peduncle *Superior Cerebellar Peduncle IPSILATERAL HEMISPHERE “ (only anterior lobe cortex) Unconscious proprioceptive input from GTO- UEs No “