9.3 MAINTAINING THE EXCRETORY SYSTEM Read p.316-325 and answer the questions that follow. 1. What is osmotic pressure? Osmotic pressure is the force generated as water moves by osmosis. 2. What are osmoreceptors? Osmoreceptors are cells that are sensitive to osmotic pressure and detect changes in water levels. 3. Draw a flow chart that describes how osmotic pressure is regulated when you are dehydrated. Increased osmotic pressure dehydrated Decreased osmotic pressure to normal Osmoreceptors in hypothamalmus tell pituitary gland to release ADH (antidiuretic hormone) Increased reabsorption of water into blood ADH travels through blood to kidneys Kidneys increase their permeability in distal tubule and collecting duct 4. Draw a flow chart that describes how osmotic pressure is regulated when your plasma is too dilute of ions. Plasma too dilute Decreased osmotic pressure Osmotic pressure increases to normal Osmoreceptors in hypothalamus prevent the release of ADH Solute concentration in blood increases Distal tubule and collecting tube become less permeable to water More water is secreted in urine 5. What is diabetes insipidus? Diabetes insipidus is an insufficient release of ADH. If you don’t have enough ADH, water cannot be reabsorbed and so you will have excessive amounts of urinating and dehydration. To restore water reabsorption you can take synthetic ADH. 6. How does alcohol affect urine production? Alcohol stimulates urine production by also decreasing ADH production, which in turn leads to water loss through urine. 7. Explain how aldosterone controls the concentration of sodium within the blood. Aldosterone is the hormone that increases the reabsorption of sodium and water and the release (secretion) of potassium (K+) in the kidney. Decreased concentration of sodium in blood Hormone aldosterone secreted by the adrenal glands above the kidneys If K+ concentration high then it is secreted from blood into distal tubule and collecting ducts Distal tubule and collecting duct reabsorb Na+ Water and Clions follow Na+ passively Net gain of ions and water into the blood 8. How do the respiratory and excretory systems work together to regulate blood pH? The kidneys keep blood pH within normal limits. They reabsorb HCO3(bicarbonate ions), and excrete H+ ions as needed to maintain the pH at about 7.4. The chemical reactions that act to maintain a constant pH are linked to the respiratory system because H2CO3 (carbonic acid) reacts in solution to form carbon dioxide and water. Therefore, levels of H2CO3 are linked to levels of CO2, which are regulated by breathing. 9. What are kidney stones? What is the treatment method for kidney stones? Kidney stones usually occur due to excess calcium in the urine. When the chemicals within the urine crystallize they can form a kidney stone. The stones can be passed through the urinary tract, or be broken down with medications. Ultrasound waves can also be used to break them down if they are less than 20 mm in diameter. If they are larger surgery to remove them may be needed. 10. What is renal insufficiency? Renal insufficiency occurs when kidney’s cannot maintain homeostasis due to damaged nephrons. 11. What is dialysis? Dialysis refers to the diffusion of dissolved substances through a semipermeable membrane. Substances more concentrated in the blood will move into the dialysate; substances more concentrated in the dialysate will move into the blood. *** want to maintain homeostasis. 12. Identify the two types of renal dialysis and briefly describe their similarities and differences. 1. HEMODIALYSIS = artificial semi-permeable membrane is attached to a person’s artery and vein in their arm; it acts as an exterior artificial kidney. 2. PERIOTONEAL DIALYSIS = the lining of the intestine (peritoneum) acts as the semi-permeable membrane; dialysate is introduced to the abdominal cavity, where the large surface area and rich supply of capillaries of peritoneum slowly filter the blood. 13. Why is kidney transplant considered a cure for a serious kidney disorder, while renal dialysis is not? Dialysis enables people with kidney disease to live their lives in a relatively unchanged way. However, dialysis is not a cure and it is not intended to be a long-term solution to the problem of kidney disease. Individuals with kidney functions of ten percent or less will eventually have to replace their kidneys. 14. What factors could affect the short-term and long-term success of a kidney transplant? The short-term success would depend on the availability of organs for transplantation, surviving surgery, and contracting an infection. Long-term success depends on the success of anti-rejection drugs and solving the problem that caused the original kidney disease.