Muscular System The Belgian Blue Breed of Cattle - the result of a mutation in which the mysostatin gene has been “knocked out” Types of Muscle TYPE CONTROL EXAMPLE The word “striated” means striped. Skeletal muscle appears striped under a microscope. Muscles and Muscle Fiber Structure Muscles are composed of many FIBERS that are arranged in bundles called _____________________ Individual muscles are separated by _______________________, which also forms _____________________________ Epiphysium = Periphysium = Endomysium = Muscle Layers Muscle at the Cell Level Sarcolemma = Sarcoplasm = Sarcoplasmic Reticulum - Myofibrils = Label 1. 2. 3. 4. 3. (same) 5. 6. 7. Myofibrils are made of ACTIN = ______________________________ MYOSIN = ______________________________ Myofilaments ACTIN (thin) and MYOSIN (thick) -- form dark and light bands • ___ band = _______ • ____________(myosin) • ___ band = _______• ______________(actin) LABEL: It is important to remember the hierarchy How Muscles Work with the Nervous System NEUROMUSCULAR JUNCTION – MOTOR END PLATE – SYNAPTIC CLEFT – SYNAPTIC VESICLES – Motor Unit or Neuromuscular Junction 1. _______________________________________________________________________ 2. _______________________________________________________________________ 3. _______________________________________________________________________ 4. _______________________________________________________________________ 5. _______________________________________________________________________ The neurotransmitter that cross the gap between the nerve cell and a muscle cell is ______________________________________________ ___________is broken down by ______________________________________________ _____________________________________________________ _____________________________________________________ _____________________________________________________ _____________________________________________________ ________________________ is stored in vesicles SLIDING FILAMENT MODEL The theory of how muscle contracts SLIDING FILAMENT THEORY (MODEL) The theory of how muscle contracts is the sliding filament theory. The contraction of a muscle occurs as the thin filament slide past the thick filaments. What is needed: ATP Calcium Myosin & Actin Acetylcholine Cholinesterase Sliding Filament Handout 1. 2. 1. 3. 3. 4. 4. 5. 5. 2. 6. 6. 7. 7. 8. 9. 8. 9. 10. 10. Energy Source _____________________________________________ _____________________________________________ _____________________________________________ _____________________________________________ _____________________________________________ __________ * Only 25% of energy produced during cellular respiration is used in metabolic processes - the rest is in the form of HEAT. - maintains body temperature. Other Terms 1. Threshold Stimulus 2. All-or-None Response 3. Motor Unit 5. Recruitment 6. Muscle Tone 7. Muscular Hypertrophy 8. Muscular Atrophy 9. Muscle Fatigue 10. Muscle Cramp 11. Oxygen Debt 1. Threshold Stimulus 2. All-or-None Response 3. Motor Unit 4. Recruitment 5. Muscle Tone 6. Hypertrophy 7. Atrophy - - 8. Muscle Fatigue - 9.Muscle Cramp - 10. Oxygen Debt *See Magic School Bus - 11. Origin and Insertion Origin = Insertion = The biceps brachii has two origins (or two heads). What is rigor mortis? What is tetanus? A tetanus shot must be administered shortly after exposure to the bacteria. Once you develop tetanus, there is no cure. See the dancing frog legs video …