Muscles and Movement Crash Course video: https://www.youtube.com/watch?v=jqy0i1KXUO4 IB Assessment Statement • State the roles of bones, ligaments, muscles, tendons and nerves in human movement. Muscles & Movement Intro • A mammalian skeleton has more than 200 bones • Some are fused; others are connected at joints by ligaments that allow freedom of movement Human Movement • Human movement is produced by the skeletal acting as simple lever machines Parts of the Muscle System IB Learning Objective • Label a diagram of the human elbow joint, including cartilage, synovial fluid, joint capsule, named bones and antagonistic muscles (biceps and triceps). IB Learning Objective Outline the functions of the structures in the human elbow joint named in cartilage, synovial fluid, joint capsule, named bones and antagonistic muscles (biceps and triceps). Muscles move skeletal parts by contracting • The action of a muscle is always to contract • Skeletal muscles are attached in antagonistic pairs, with each member of the pair working against each other LE 49-27 Human Grasshopper Extensor muscle relaxes Biceps contracts Biceps relaxes Triceps contracts Flexor muscle contracts Forearm flexes Triceps relaxes Tibia flexes Extensor muscle contracts Forearm extends Tibia extends Flexor muscle relaxes Joint structure and antagonistic muscle pairs (example: Elbow Joint) A. Humerus (upper arm) bone. B. Synovial membrane that encloses the joint capsule and produces synovial fluid. C. Synovial fluid (reduces friction and absorbs pressure). Joint structure and antagonistic muscle pairs (example: Elbow Joint) D. Ulna (radius) the levers in the flexion and extension of the arm. E. Cartilage (red) living tissue that reduces the friction at joints. F. Ligaments that connect bone to bone and produce stability at the joint. Antagonistic Pairs (example: Elbow Joint) • To produce movement at a joint m • uscles work in pairs. • Muscles can only actively contract and shorten. • They cannot actively lengthen. Antagonistic Pairs (example: Elbow Joint) • One muscles bends the limb at the joint (flexor) which in the elbow is the biceps. • One muscles straightens the limb at the joint (extensor) which in the elbow is the triceps. Elbow joint structure & function 1. Humerus forms the shoulder joint also the origin for each of the two biceps tendons 2. Biceps (flexor) muscle provides force for an arm flexion (bending). As the main muscle it is known as the agonist. 3. Biceps insertion on the radius of the forearm Elbow joint structure & function • 4. Elbow joint which is the pivot for arm movement • 5. Ulna bone one of two levers of the forearm Elbow joint Structure & Function • 6. Triceps muscle is the extensor whose contraction straightens the arm. • 7. Elbow joint which is also the pivot (fulcrum)for this movement. Animations on Muscles • http://www.freezeray.com/flashFiles/antagoni sticPair.htm IB Learning Objective • Compare the movements of the hip joint and the knee joint. Movement at the hip and knee joint: Knee • The knee joint is an example of a hinge joint. • The pivot is the knee joint. • The lever is the tibia and fibula of the lower leg. Movement at the hip and knee joint: Knee • A knee extension is powered by the quadriceps muscles. • A knee flexion (bending) is powered by the hamstring muscles. • Movement is one plane only. Movement at the hip and knee joint: HIP • Rotation is in all planes and axis of movement. • The lever is the femur and the fulcrum is the hip joint. • The effort is provided by the muscles of quadriceps, hamstring and gluteus. Comparison of Hip and Knee Joint Pivot Bones at Lever Joint Flexion/ effort Hip Femur Quadriceps Hamstrings Many Tibia Hamstring one Pelvis/ Femur Knee Tibia/ Femur Extension/ effort Quadriceps Planes of movement Joint Animation • http://www.midsouthorthopedics.com/educat ion.htm • http://www.freezeray.com/flashFiles/hipJoint. htm • http://choroknamu.com/tt/site/db/board/om _gungol/upload/1_10000/1692/is_en_pt_kne e.swf IB Learning Objective Describe the structure of striated muscle fibres, including – the myofibrils with light and dark bands, – mitochondria, – the sarcoplasmic reticulum, – nuclei – and the sarcolemma. Muscles • Tendons – Bones and muscles are connected via non-elastic structures called tendons. • • 1. Tendon connecting muscle to bone. These are non-elastic structures which transmit the contractile force to the bond. 2. The muscle is surrounded by a membrane which forms the tendons at its ends. Muscle Fibres • A skeletal muscle consists of a bundle of muscle fibres. • A muscle fibre consists of long multinucleate cells. Muscle bundle which contains a number of muscle cells The plasma membrane of a muscle cell is called the sarcolemma and the membrane reticulum is called . the sarcoplasmic reticulum Ultrastructure of a skeletal muscle • Skeletal muscles consist of many muscle fibres cells. • Muscle fibre consist of many parallel myofibril within a plasma membrane called a sarcolemma Ultrastructure of a skeletal muscle • The cytoplasm of the cell contains many mitochondria. Ultrastructure of a skeletal muscle • The cell membrane (sarcolemma) folds inside the cell forming a transverse tubular endoplasmic reticulum called the sarcoplasmic reticulum Electron Micrograph of a muscle fibre cell. Muscle Fibre Cell • There are many parallel protein structures inside called myofibrils. • Myofibrils are combinations of two filaments of protein called actin and myosin. IB LEARNING OBJECTIVE Draw and label a diagram to show the structure of a sarcomere, including – Z lines, – actin filaments, – myosin filaments with heads, – and the resultant light and dark bands. Actin & Myosin – Actin in muscles cells consist of two strands thin filaments and one strand of regulatory protein called tropomyosin. Actin & Myosin – Myosin are staggered arrays of thick filaments – Myosin molecules have bulbous heads with protrude from the filament. These bulbous head will bond to binding sites on the actin filament Actin & Myosin • The filaments of actin and myosin overlap to give a distinct banding pattern when seen with an electron microscope. Banding pattern of actin & myosin filaments on a electron micrographs Banding Pattern of muscle fibre cells • Skeletal muscle are called striated muscle because of this banding pattern • Banding is cause by regular arrangement of actin and myosin that create a pattern of light and dark bands • Each unit is a sarcomere (cell membrane), bordered by Z lines Banding Pattern of Muscle Cells IB LEARNING OBJECTIVE • Explain how skeletal muscle contracts, including the release of calcium ions from the sarcoplasmic reticulum, the formation of cross-bridges, the sliding of actin and myosin filaments, and the use of ATP to break crossbridges and re-set myosin heads. Mechanism of muscle contraction • 1. An action potential arrives at the end of a motor neuron, at the neuromuscular junction. • 2. This causes the release of the neurotransmitter acetylcholine. Mechanism of muscle contraction • 3 This initiates an action potential in the muscle cell membrane. • 4. This action potential is carried quickly throughout the large muscle cell by invaginations in the cell membrane called T-tubules. Mechanism of muscle contraction • 5. The action potential causes the sarcoplasmic reticulum (large membrane vesicles) to release its store of calcium into the myofibrils. • For a muscle fiber to contract, myosin-binding sites on the actin fibre must be uncovered • This occurs when calcium ions (Ca2+) bind to a set of regulatory proteins, the troponin complex – making the binding sites exposed Actin Filament Contracted vs. Relaxed Muscle • This exposed myosin-binding sites bond with the bulbous heads (cross bridge) of myosin filament. • Cross bridges include an ATPase enzyme which can oxidise ATP and release energy. • The cross bridge swings out from the myosin (thick filament) and attaches to the actin (thin filament). • The cross bridge (bulbous head) changes shape and rotates through 45°, causing the filaments to slide. The energy from ATP is used for this “power stroke” step. • A new ATP molecule binds to myosin and the cross bridge detaches from the Actin (thin filament). • The cross bridge changes back to its original shape, while detached (so as not to push the filaments back again). • It is now ready to start a new cycle, but further along the thin filament. Electron micrographs of muscle fibre contraction. Electron micrographs of muscle fibre contraction. If electron micrographs of a relaxed and contracted myofibril are compared it can be seen that: •These show that each sarcomere gets shorter (Z-Z) when the muscle contracts, so the whole muscle gets shorter. •But the dark band, which represents the thick filament, does not change in length. •This shows that the filaments don’t contract themselves, but instead they slide past each other. Muscle Contraction Animations • http://brookscole.cengage.com/chemistry_d/templates/student_resource s/shared_resources/animations/muscles/muscles.html • http://media.pearsoncmg.com/bc/bc_campbell_biology_6/cipl/ins/49/HT ML/source/71.html • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter10/animation__action_ potentials_and_muscle_contraction.html • http://www.lab.anhb.uwa.edu.au/mb140/corepages/muscle/muscle.htm# CONTRACT • http://www.sumanasinc.com/webcontent/animations/content/muscle.ht ml Muscle Contraction tutorial • https://www.youtube.com/watch?v=zopoN2i7 ALQ