BIOL30001 Reproductive Physiology Introduction to the Subject Geoff Shaw Mark Green Contact: BIOL30001@zoology.unimelb.edu.au Reading: - LMS.unimelb.edu.au - Johnson MH (2013) Essential Reproduction 7th Edition, WileyBlackwell - Shaw G (2005) “Animal Reproduction” chap 19 in Biology: An Australian Focus, 4th edition. Knox et al. McGraw-Hill BIOL30001 Icebreaker Quiz What proportion of Australian couples who want to have a child require medical intervention to conceive? BIOL30001 Icebreaker Quiz Where does the majority of human seminal fluid come from? BIOL30001 Icebreaker Quiz What is this organ and what does it do? BIOL30001 Icebreaker Quiz Is testosterone important for female reproduction? BIOL30001 Icebreaker Quiz Are germ cells infectious? BIOL30001 Icebreaker Quiz How many days is pregnancy in humans? mice sheep bandicoots http://en.wikipedia.org/wiki/File:Pregnancy_26_weeks_1.jpg Subject Outline Focus on mammals 64,000 pubs in 2013 67,000 pubs in 2014 Subject Outline Knowledge of • Structure, function, and development of the reproductive organs (Male & Female); • Endocrine and neuroendocrine and environmental control of – reproduction, – mating, – fertilisation, – pregnancy, – parturition and – lactation in vertebrates; and • Human intervention in the reproductive process • Common human reproductive diseases and disorders Subject Outline • Generic skills: – Attain knowledge from lectures, tutorials, observation and the literature – use that knowledge to evaluate and communicate results – access information in primary scientific literature – abilities to evaluate scientific evidence critically – skills in data interpretation, and identifying alternative explanations • We will assess your understanding – note learning is not enough. • Lectures- Mon, Tues, Weds, Fri – but Friday lec. slot mainly for tutes (may run impromptu tutes in the extra slots) Lecture: should NOT be “the process by which the notes of the lecturer become the notes of the student without passing through the mind of either” Focus on what is being said; ask questions… • Tutorials – quizzes – structured learning exercises – raise questions on lecture content • Assessment – 35% Seven online quizzes – 15% Literature review – 10% 50 minute mid-semester test – 40% end of semester exam Electronic Communication • Notices in the Announcements area in LMS • Emails (we will use your University of Melbourne email address) • Electronic forums/discussion boards on LMS (feel free to contribute to these) • Direct to us on BIOL30001@zoology.unimelb.edu.au Check all of these regularly! Feedback • Continuous assessment (e.g. online quizzes and mid-semester test) • Lecture-time, tutes, quizzes & lit review assignment • Seek us out at other times (but forgive us if we are busy) **Please remember there are ~200 students in this subject** Teaching Staff Co-ordinators Geoff Shaw, Rm 359 Ph 8344 6267 Textbook Mark Green, Rm 354 Ph 8344 4346 Martin Johnson BIOL30001@zoology.unimelb.edu.au Guest Lecturers Teaching Assistants www.essentialreproduction.com Time: 170 h Total time commitment Total number of hours (contact hours plus non-contact time commitment) through the semester expected of a student with average preparation to successfully complete the subject and achieve an average mark. The total time commitment for 12.5 point undergraduate subjects is 170 hours UOM Policy MPF1015 Time includes self study Aim to complete at least 10 hours study for BIOL30001 EVERY WEEK including semester break and swot vac. Contact: 34 lectures 6 mandatory tutes 7 Quizzes Self Study: 72 hours PER WEEK: 4 hours 6 hours 10 hours TIME: don’t rely on swotvac • Don’t pretend that doing nothing in term then cramming for hours in swot vac is enough. • This is a subject with a large amount of content, which is why we encourage you to review what you have learnt frequently (online quizzes). TIME: keep up to date • WE ASSUME in Lecture 2 that you know the material covered in Lecture 1; In lecture 3 we assume Lecture 1 & 2…. … make sure you keep up-to-date with your revision and self-assessment TIME: do something every week • Spread your time investment through the semester. • We will encourage you to study regularly with approx. weekly quizzes (35% of assessment) TIME: don’t get behind • If you get behind you will never really catch up! Spend some time after EVERY lecture and tute consolidating what you have learned. • Use your textbook, our notes on LMS, Echo360, or other books or resources. BIOL30001 Reproductive Physiology Patterns of Reproduction Geoff Shaw School of BioSciences Reading: - Subject handbook - Shaw G (2005) “Animal Reproduction”. Chapter 18 in Knox et al. Biology 3rd Ed. - The world wide web… Why Study Reproduction? • • • • • Fundamental to life Farming Fascinating Fun Future of human civilization Patterns of reproduction • Asexual • Sexual Asexual • fission • budding • parthenogenesis hydra aphids whiptail skink • no exchange of genetic information - clonal Sexual • Exchange of genetic information • bacteria etc. • 2 sexes – female / male + …? sperm • female – eggs – large embryo • male – sperm – small, motile • meiosis vs mitosis fertilised wallaby egg 0.1 mm Variations on a theme protogyny • Hermaphrodites protandry • Parthenogenesis Question: • what selective pressures may favour evolution of protandry vs protogyny? Sex and the echiuroid worm Bonellia Echiuroid worm - Bonellia • Female worm is rock dwelling • Male lives inside the female’s uterus & fertilizes her eggs • If larva lands on sea floor becomes female • If larva lands on the proboscis of a female - chemical attractants emitted • Larva will enter females mouth, migrate to the uterus and differentiate into a male 1m 10 cm 3 mm Rates of pregnancy birth and abortion per 1000 women aged 15-19 in USA in the year 2010 Pregnancies: Births: Abortions: 57 35 15 source: Sedgh et al (2015) J Adol Health 56:223-230 http://www.sciencedirect.com/science/article/pii/S1054139X14003875 Rates of pregnancy birth and abortion per 1000 women aged 15-19 in USA year 2010 pregnancies: 57 births: 34 abortions: 15 World Population Growth… <1% North America, Europe, Russia, Australia, NZ 1-2% Brazil, Argentina, Chile, China, India, Indonesia 2-3% many countries in Central America, Africa, PNG, Asia >3% many countries in Africa & Asia Demographic patterns Age group 45-85+ 15-44 0-14 Rapid growth Kenya Nigeria Saudi Arabia Slow growth US Australia Canada Zero growth Negative growth Denmark Germany Austria Bulgaria Italy Hungary