Grand Rounds Brittni M. Smith Middle Tennessee State University February 14, 2008 Patient Demographics Female Caucasian 50 years of age Height: 5 ft. 3 in. Weight: 107 lbs. Married, no children Events Prior to Hospitalization Hospitalized 12/2007 for GI bleed D/C on 01/08 01/12 home, episode of hematemesis and dizziness Presented to ER with hematemesis, syncope, sinus tachycardia, and SBP of 60 Risk Factors Portal Hypertension Esophageal Varices Prior bleeding episodes Increased abdominal pressure Admitting Medical Diagnosis Gastrointestinal Bleed r/t Esophageal Varices (4) Obstruction of venous flow (portal HTN) Increased pressure in portal vein Thin walled varicosities Rupture / hemorrhage Tx: band ligation Additional Medical Diagnoses Prior to Admission: Pancreatic Portal Cancer HTN GERD Hypothyroidism Post Admission: Right hepatic lobe abscess Splenomegaly Ascites Pleural Effusion Laboratory Values Lab Result red=high blue=low Normal Range Reason for Abnormality RBC 3.07x10/ul 4.0-5.4 hemorrhage WBC 15.4mm^3 4.3-10 Hgb 8.8% 12-16 liver abscess hemorrhage Hct 27.5% 35-47 hemorrhage Laboratory Values Lab Result red=high blue=low Platelets 126mm^3 Normal Range Reason for Abnormality 150-400mm splenomegaly Creatinine 0.3mg/dl 0.5-1.1 T. Protein 4.3g/dl 6.3-8.3 Albumin 2.1g/dl 3.8-5.0 muscle wasting muscle wasting malnutrition Laboratory Values Lab Result red=high blue=low Normal Range Reason for Abnormality Bilirubin T. 1.6mg/dl 0.3-1.1 portal HTN ALP 138units/L 32-119 portal HTN ALT 46units/L 9-43 liver abscess Blood Culture pending Diagnostics Test Reason Results Chest X-ray Baseline study Abdominal US Abdominal distention/ firmness W/O masses, edema, pneumo splenomegaly, ascites, irregular shaped liver Abdominal CT Comparison from 12/27/07 R hepatic lobe abscess Diagnostics Test Transthorasic Echocardiogram Reason R/O endocarditis Results Large pleural effusion left lung Medications Medication Colace docusate sodium Class/ Dose Route/ Frequency Rationale for Use Laxative, emollient stool softener, 100mg PO BID prevent Nexium esomeprazole Proton Pump Inhibitor Duragesic fentynl Opioid analgesic 50mcg TD q72h 40mg in 5ml INJ BID constipation treat and prevent gastric ulcers chronic pain r/t cancer Medications Medication Class/ Dose Route/ Frequency Rationale for Use Pancreatic hormone lower blood Novolin R short acting insulin WBG-100/15= #u glucose levels SUBQ q6h Synthroid Levothyroxine Thyroid hormone 50mcg PO daily thyroid hormone replacement Medications Medication Class/ Dose Route/ Frequency Rationale for Use Merrem Meropenem Ultra-Broad Tx for liver Spectrum abscess Antibiotic 1g in 100ml IVq8h Zosyn piperacillintazobactam Extended Spectrum Beta-Lactam Antibiotic 3.375g in 100ml IV q6h Tx for liver abscess Medications Medication Class/ Dose Route/ Frequency Rationale for Use Vancocin vancomycin Glycopeptide Antibiotic 750mg in 100ml IV q12h Tx for suspected MRSA infection Tylenol acetaminophen Nonopiod analgesic 650mg PO q6h PRN mild to moderate pain Medications Medication Class/ Dose Route/ Frequency Rationale for Use Dulcolax bisacodyl Laxative, stimulant 10mg rectal q12h PRN Tx for constipation Diazepam valium Antianxiety 2.5mg in 100 ml IV TID PRN Morphine Opioid analgesic 4mg IV q4h PRN muscle relaxant and decrease anxiety moderate to severe pain Medications Medication Zofran odenastone sodium chloride NaCl TPN Class/ Dose Route/ Frequency Antiemetic 4mg IV q4h PRN Rationale for Use prevention, Tx of nausea/ vomiting Isotonic 0.9% Fluid 1000ml @ 30ml/h replacement, keep vein open IV continuous 1440ml @ 60ml/h source of IV continuous nutrition Collaboration Physicians Nurses Dieticians Instructors Peers Assessment Respiratory Cardiovascular Neurological GI/GU Musculoskeletal Skin/IV Psychosocial Neurological Alert, oriented x3 Pupils 2mm bilaterally, briskly reactive Followed verbal commands Clear speech pattern Recent, remote memory intact Full ROM in RUE, LUE Weakness present RLE, LLE Respiratory Respirations 16/min SpO2 96% O2 @ 2L NC Coarse bilaterally Diminished in bases bilaterally No wheezes or ronchi present Cardiovascular Heart rate 107 beats/min Sinus tachycardia S1, S2 present BP 112/88 Peripheral pulses present Capillary refill >3 sec Edema 2+, non-pitting feet/ankles bilaterally Gastrointestinal / Genitourinary Bowel sounds active in all four quadrants Abdomen firmly distended Hepatic drain in RLQ- dark green/red Foley catheter draining clear yellow urine TPN @ 60ml/h Integumentary Dry, pink, appropriate for ethnicity Fingers and toes cool, core temp warm Central line site clean, no redness, edema or drainage present Hepatic drain site clean, dry Psychosocial Anxious, apprehensive Fearful Denial Positive mood Numerous visitors Husband present Research Animal Fat Consumption and Pancreatic Cancer Study investigated correlation between animal fat consumption and incidence of pancreatic cancer Data obtained from 35 countries Meats included: beef, veal, pork, poultry Results: animal fat consumption increases the incidence of pancreatic cancer Nursing Diagnosis # 1 Ineffective Tissue Perfusion related to bleeding of esophageal veins as evidenced by increased heart rate, capillary refill greater than 3 seconds, and cool extremities Goals 1. Patient will have pulse rate of 60-100 beats/min during shift 2. Patient will have capillary refill time less than 3 seconds during shift 3. Patient will have warm perfused extremities during shift Interventions Encourage patient to increase fluid intake Place patient in an upright position Provide client with adequate clothing and extra blankets Maintain room temp above 70 degrees Administer IV fluids as ordered Evaluation 1. Partially met: patient’s pulse ranged from 94-106 2. Met: patient’s capillary refill time was less than 3 seconds 3. Met: patient’s hands, fingers, feet, and toes were warm and perfused Nursing Diagnosis # 2 Acute pain related to distention and increased pressure in esophageal veins as evidenced by restlessness, increased heart rate, and patient’s verbalization of pain Goals 1. Patient will have a pain score of 2 or less on a 0-10 scale during shift 2. Patient will verbalize a decrease or absence of pain 3. Patient will exhibit a decrease in restlessness related to pain Interventions Elevate HOB 30 degrees or more as tolerated Administer pain medications at scheduled times Provide ice water for drinking Provide distraction: TV, music, visitors Evaluation 1. Met: Patient rated pain as a 0 or 1 2. Met: Patient stated a decrease in pain level 3. Met: Patient remained comfortable and relaxed throughout the day Nursing Diagnosis #3 Imbalanced nutrition: less than body requirements related to esophageal pain and venous distention as evidenced by muscle wasting, refusal to eat, and use of total parenteral nutrition Goals 1. Patient will remain at current weight or greater 2. Patient will have no new evidence of muscle wasting 3. Patient will increase the amount of food and fluid intake during meals Interventions Patient will sit in an upright position while eating Diet will consist of soft bland foods Encourage fluid intake Add ice to liquids Administer TPN as scheduled Evaluation 1. Met: Weight on admission 107lb. Weight on day of care 107lb 2. Unmet: Patient exhibited extreme weakness in legs 3.Met: Patient drank two 240ml cans of Ensure and consumed approx. 50% of breakfast and lunch References Ignatavicius, D.D. & Workman, M.L. (2006). Medical Surgical Nursing: Critical Thinking for Collaborative Care. St. Louis: Elsevier Saunders. Mattson, C.P. (2005). Pathophysiology: Concepts of Altered Health States. Philadelphia: Lipincott Williams & Wilkins. Pagana, K. D. & Pagana, T.J. (2007). Mosby’s Diagnostic and Laboratory Test Reference. St. Louis: Mosby Elsevier. Skidmore-Roth, L. (2007). Mosby’s Drug Guide for Nurses. St. Louis: Mosby Elsevier. References Ulrich, S. P. & Canale, S. W. (2005). Nursing Care Planning Guide for Adults in Acute, Extended, and Home Care Settings. St. Louis: Elsevier Saunders. www.astrazeneca.com. Retrieved February 6, 2008. www.vancocin.com. Retrieved February 6, 2008. www.wikipedia.com. Retrieved February 6, 2008. Zhang, J., Zijin, Z., & Berkel, H. J. (2005, August). Animal fat consumption and pancreatic cancer incidence: evidence of interaction with cigarette smoking. Annals of Epidemiology. 15(7), 500-508. Retrieved February 6, 2008 from CINHAL database.