Fayetteville State University College of Arts and Sciences Department of Biology BIOL 670 Physiology Fall 2012 I. Locator Information Instructor Credit Hours Course Location/Meeting Time: Total Contact Hours Office Hours Office Location Telephone E-mail Dr. Stephen J. Salek 4.00 TR 4:00-5:50 LSA 247 3.00 MWF 10-12 R 11-1 LSA 340 (Aquatic Research Lab) use email before calling 672-2103 ssalek@uncfsu.edu FSU Policy on Electronic Mail: Fayetteville State University provides to each student, free of charge, an electronic mail account that is easily accessible via the Internet. The university has established email as the primary mode of communicating with enrolled students about impending deadlines, upcoming events, and other information important to student progression at the university. Students are responsible for reading their email on a regular basis to remain aware of important information disseminated by the university. The university maintains open-use computer laboratories throughout the campus that can be used to access electronic mail. Students making inquiries via email to FSU faculty and staff about academic records, grades, bills, financial aid, and other matters of a confidential nature are required to use their FSU email account. Rules and regulations governing the use of FSU email may be found at: http://www.uncfsu.edu/PDFs/EmailPolicyFinal.pdf II. COURSE DESCRIPTION Biology 670 An analysis of the functions of major organ systems, especially in mammals, with attention to and discussions of the effects of extreme environments on mammalian physiology. Computer simulated laboratory exercises reinforce lecture topics. Prerequisite: Undergraduate or graduate course in physiology and a willingness to put in plenty of study time. III. Disabled Student Services: In accordance with Section 504 of the 1973 Rehabilitation Act and the Americans with Disabilities Act (ACA) of 1990, if you have a disability or think you have a disability to please contact the Center for Personal Development in the Spaulding Building, IV. TEXTBOOKS 1. Human Physiology and Mechanisms of Disease 6 th edition Guyton an Hall (1997) ISBN 0-7216-32998 2. Life at the Extremes: The Science of Survival. Frances Ashcroft ISBN 0520234200 3. PhysioEx is on line at: http://wps.aw.com/wps/media/access/Pearson_Default/5255/5381923/login.html ** Text books are available at the bookstore. V. Student Learning Outcomes By the end of this course each student should be able to: 1. Demonstrate full knowledge of cell physiology. This will be measured by having the student sketch a picture of a generalized cell labeling, and describing the function of each part, and answering exam questions about major chemical pathways in cells and organelles. 2. Recall the concept and components of homeostatic systems, describing how cells, tissues, organs and organ systems maintain important physiological set points. This will be measured by quiz and exam scores. 3. Explain how cell membrane constituents function in creating membrane potentials. This will be measured by quiz and exam scores. 4. Write and answer detailed questions about how membrane potentials are propagated, converted to chemical signals (neurotransmitters) at synapses, and create postsynaptic potentials. This will be measured by exams, quizzes and student generated questions in class discussions. 5. Identify and explain the function of different types of neurons, and structures in the central nervous system. This will be measured by lecture and laboratory exams. 6. The student will be able to explain the functional organization of the nervous system. This will be measured by lecture exams and quizzes. 7. Identify the components of a reflex arc. This will be measured by lecture and laboratory exams. 8. Describe the components (afferent and efferent) of the peripheral nervous system. This will be measured by lecture and laboratory exams. 9. Compare and contrast the sympathetic and parasympathetic nervous systems, their neurons, neurotransmitters, receptor types and functions. This will be measured by lecture and laboratory exams and discussion of student written exam questions in class. 10. Understand and answer questions about sensory cells including both the somatic and special types of sensory cells including receptors found in the cutaneous, visual, auditory, olfactory, gustatory, equilibrium structures. Explain the mechanism of sensory transduction in each. This will be measured by lecture and laboratory exams. 11. Describe and answer questions about the structure and function of muscles on the organ, tissue, cellular, and subcellular levels. This includes the three muscle types and sliding filament theory. This will be measured by lecture and laboratory exams. 12. Write and answer questions about the functional characteristics of blood, blood vessels and the heart. This will be measured by lecture and laboratory exams. 13. Be able to answer detailed questions about the components and processes of the cardiac cycle. This will be measured by lecture and laboratory exams. 14. Identify and explain the function of all components of the immune system. Compare and contrast its specific and nonspecific functions. This will be measured by lecture and laboratory exams. 15. List all the endocrine glands and cells. Explain what hormones are produced by each and the function of each hormone. This will be measured by lecture and laboratory exams. 16. Answer and write detailed questions about second messenger systems and the mechanism of action of all hormones. 2 17. Compare and contrast the function of both the endocrine and nervous systems, and explain how each one contributes to maintaining homeostasis in the body. 18. Describe the anatomy and function of the renal system, including organs, nephrons and their components, and how the kidney functionally generates both a concentrated and dilute urine. This will be measured by lecture and laboratory exams. VI. Course Requirements and Evaluation Criteria All assignments must be completed by or before the date and time listed on the schedule page. These dates and times will be clearly stated ahead of time in the syllabus and on the schedule page. I will not accept late work, and will issue a zero for all late work with the exceptions listed below (see “Tardy and Incomplete work”). All complaints and concerns should initially be made to me before bringing them to any other university employee. A short in person discussion usually resolves issues quickly. All students must send me an email stating that they agree to the terms in this syllabus. You should carefully consider all course policies before taking this course. ATTENDANCE AND WITHDRAWAL You are expected to complete all work. If you are not able to turn in your assignments during a particular week, they must be turned in prior to that week, not after that week. If you must withdraw from the course it is YOUR responsibility to complete the necessary paperwork for the withdrawal. If you stop completing assignments without officially withdrawing from the course, you will receive the grade earned based on your point total (at the time you stop attending) divided by the maximum points (as if you had completed ALL work). This usually means a grade of F will be recorded. If you do not interact with the course by 8/28/2012, you will be considered a no show (see below) and an interim grade if “X” will be entered. It is the student’s responsibility to carefully look at all due dates at the beginning of the semester and adjust their schedules to accommodate assessment deadlines. Any student unwilling to do this must drop the class immediately. EVALUATION CRITERIA Assignments Points 4 Exams 100 each (lowest dropped) PhysioEx labs 80 Laboratory exams (2) 25 pts ea. 50 70-140 Ashcroft discussion or student lecture Final exam (cannot be dropped) 100 Total (tentative) 600-740 pts total *See grading scale below I grades Incompletes will be given in extraordinary circumstances only. In the event that an “I” is issued, the student must submit a list of all incomplete assessments by email. In addition, the student must research and indicate the date when the incomplete will be turned to an F if the work is not turned in. The instructor will reply confirming or correcting this list and date. When the work has been completed, the student must contact me via email and indicate when the work will be turned in. When we agree on a date and time, the student must submit all of the work at one time (by email). I will not grade any assessments that are turned in days, months, or weeks apart. Exams Exams will be given either through the blackboard system or in class. You will be tested on lectures, readings, discussions, and lab material. The exam format is a combination of multiple choice, matching, true or false, multiple answer and long and short essay questions. It is the student’s responsibility to carefully look at all due dates at the beginning of the semester and adjust their schedules to accommodate assessment deadlines. If you cannot keep the deadlines I strongly suggest you drop the class immediately. In BIOL 670, exams and lab exams are closed book. You may not use any resources for aid on these. Obtaining or viewing of prior copies of exams is considered cheating. Distributing or discussing exam questions is considered cheating. Using any textbooks or websites is considered cheating. 3 Tardy and Incomplete work I do not accept late work without a reasonable excuse. Examples of these include unexpected illnesses accompanied by a doctor’s note, or the death of an immediate family member. Each assignment will have a due date listed under the blackboard assignments link. If you submit your work after this deadline, I will not read it unless you have provided a sanctioned excuse. Traveling to a location that has no internet connection will not be considered a valid excuse for incomplete work. Submitting internet laboratory exercises There is no laboratory manual for this class. Instead, you will complete all your lab exercises on the internet Through the PhysioEx website. On your black page under assignments, There will be a link for each online lab quiz. These are open book lab quizzes. You must answer the questions here to receive credit for each lab quiz. There will be two closed book lab exams in addition to these quizzes. Dishonesty in Academic Affairs Acts of dishonesty in any work constitute academic misconduct. Such acts include cheating, plagiarism, misrepresentation, fabrication of information, and abetting any of the above. Plagiarism in particular presents pitfalls to be avoided: failure to document any words, ideas, or other contributions that do not originate with the author constitutes plagiarism. Widespread use of the World Wide Web (Internet) requires particular attention to proper documentation practices. Actions outlined in the Fayetteville State University Student Handbook under Disciplinary System and Procedures will be followed for incidents of academic misconduct. The handbook may be obtained from the Office of Student Affairs located in the Collins Administration Building. Academic Integrity Policy and Procedures Academic dishonesty is the giving, taking, or presenting of information or material by a student with the intent of unethically or fraudulently aiding oneself or another on any work which is to be considered in the determination of a grade or the completion of academic requirements. In BIOL130 exams and lab exams are closed book. You may not use any resources for aid on these. Lab quizzes and assignments are open book. You may use resources, but you must write in your own words and not copy text from any other source. You may not obtain copies of my exams from anyone and study them. You may not print, distribute, or discuss questions or copies of my exams with anyone. You are cheating if you do either of these. 1. Violations A student shall be guilty of a violation of the Academic Dishonesty Policy if he or she engages in act(s) of: a. Facilitating Academic Dishonesty. Such conduct includes, but is not limited to, giving unauthorized assistance to another in order to assist that person in cheating or plagiarizing. b. Attempt. Such conduct shall include attempting any act that if completed would constitute a violation as defined herein. c. Cheating. Such conduct includes, but is not limited to, a student receiving unauthorized aid or assistance on any form of academic work. d. Falsification. Such conduct shall include the unauthorized changing of grades or conduct involving any untruth, either spoken or written regarding any circumstances related to academic work. e. Plagiarism. Plagiarism includes, but is not limited to, copying the language, structure, ideas and/or thoughts of another, without giving appropriate recognition and/or adopting the same as one’s own original work. Tentative Grading Scale: Grade Numerical equivalent (% of total points) 92-100 83-91 73-82 72-64 < 63 A B C D F Graduate students need to have a grade of C minimum to pass. 4 REVISION OF GRADES – STUDENT RESPONSIBILITIES The following revisions became effective on August 16, 2007. WN GRADE DISCONTINUED: WN - Withdrawal due to non-attendance - discontinued, effective August 16, 2007. STUDENTS: Do not expect faculty to withdraw you for non-attendance. Drop or withdraw* from classes according to the deadlines published in the catalog. *See warning below about class withdrawals. NEW TYPE OF GRADE: INTERIM GRADES – (New name for “midterm grade,” with additional purposes). Interim grades will be assigned from the first week of the semester until the deadline for class withdrawals. Interim grades are used for informational and warning purposes only; they are not part of your permanent transcript and have no effect on your GPA. Instructors may assign interim grade of F to warn students of poor academic performance or they may assign “X” or “EA” grades. (See below for explanations) After midterm, faculty will assign all students an interim grade of A – F to inform students of their academic status as of midterm. INTERIM GRADE X = NO SHOW – Assigned to students who are on a class roster, but never attend class. For warning purposes only; NOT a final grade. STUDENTS: Check interim grades early in the semester. If you have an X grade, either begin attending the class or withdraw* from it. *See warning below about class withdrawals. If you do not take action in response to an X grade, you will receive a final grade of FN. (See “FN” below) INTERIM GRADE EA = EXCESSIVE ABSENCES - Assigned to students whose class absences exceed 10% of the total contact hours. For warning purposes only, NOT a final grade. STUDENTS: Check your interim grades often. If you have an “EA” grade for a class, you are in jeopardy of failure if you do not take immediate actions. Either resume attending the class or withdraw from it. *See warning below about class withdrawals. NEW FINAL GRADE: FN = FAILURE DUE TO NON-ATTENDANCE – Assigned to students who are on class roster, but never attend the class. An FN grades is equivalent to an F grade in the calculation of the GPA. STUDENTS: You must attend (or withdraw* from) all the classes for which you are enrolled. *See warning below about class withdrawals. WARNING ABOUT CLASS WITHDRAWALS: When you withdraw from a class, you are wasting your money and time. You receive no refund for withdrawing from individual classes and you slow your progress toward degree completion. If you withdraw from or fail more than one-third of your classes, you will no longer be eligible for financial aid. STRIVE TO EARN CREDIT FOR ALL THE CLASSES IN WHICH YOU ENROLL; WITHDRAW FROM CLASSES ONLY WHEN IT IS ABSOLUTELY NECESSARY! Final Grades – This policy became effective on August 16, 2007 Grade A B C D F FN Credit Hours Hours attempted and earned Hours attempted and earned Hours attempted and earned Hours attempted and earned Hours attempted – Not earned Hours attempted – Not earned Quality Points 4 per credit hour; 3 per credit hour 2 per credit hour 1 per credit hour 0 per credit hour 0 per credit hour Meaning Exceptionally high Good Satisfactory Marginally passing Failing Failing due to non-attendance. (Student registered, but never attended.) W Hours attempted – Not earned No impact on GPA P Hours attempted and earned No impact on GPA Hours attempted – Not earned No impact on GPA Class withdrawal prior to deadline (see Academic Calendar) Satisfactory - Assigned only in classes specified as Pass/Fail Withdrawal from all classes for semester or term Auditing WU AU Hours attempted – Not earned No impact on GPA VII. Academic Support Resources Use the external links on your blackboard site. 5 VIII. Course Schedule Date Week 1 8/12 Week 2 8/19 Topic Introduction The Cell and General Physiology Assignments Guyton 1-4 Worksheet Guyton 5 Online Notes Online Lectures Membrane and and Action Potentials Animation link Worksheet Ashcroft Ch 3 Laboratory Assignment Introduction PhysioEx 11 Neurophysiology of nerve impulses Check under "assignments" Take the assessment entitled "PhysioEx 11" This is an open book assessment with no time limit. Ashcroft discussion 3 Week 3 8/26 Neuromuscular Transmission Smooth and Skeletal Muscle Contraction Guyton 6,7 Online Notes Online Lectures Worksheet Ashcroft Ch 5 PhysioEx 9 Skeletal muscle physiology Check under "assignments" Take the assessment entitled "PhysioEx 9" This is an open book assessment with no time limit. Ashcroft discussion 5 Week 4 9/2 M 9/3 Holiday The Heart and Electrocardiogram EXAM 1 CH 1-7 Guyton 8-10 Online Notes Online Notes 2 Online Lectures Worksheet 6 Exam I Week 5 9/9 Circulation Capillary Dynamics Guyton 11-18 Online Notes Online Lectures Worksheet (very long) Ashcroft Ch 1 PhysioEx 19 Cardiovascular dynamics Check under "assignments" Take the assessment entitled "PhysioEx 19" This is an open book assessment with no time limit. Ashcroft discussion 1 Week 6 9/16 The Lymphatic System Guyton 13 Online Notes Animations from UMD (watch both about the lymphatic system) See worksheet for week 5 Ashcroft Ch 7 PhysioEx 25 Renal system Check under "assignments" Take the assessment entitled "PhysioEx 25" This is an open book assessment with no time limit. Ashcroft discussion 7 Week 7 9/23 Renal Physiology I EXAM II CH 11-18 Guyton 20-21 Online Notes Online Lectures Worksheet Guyton 22-23 Week 8 9/30 Renal Physiology II Online Notes Online Lectures Worksheet Ashcroft Ch 4 Exam II PhysioEx 26 Acid base balance Check under "assignments" Take the assessment entitled "PhysioEx 26" This is an open book assessment with no time limit. Ashcroft discussion 4 Guyton 27-29 Week 9 10/7 Respiratory Physiology I Online Notes Online Lectures Worksheet Ashcroft Ch 7 PhysioEx 22 Respiratory system mechanics Check under "assignments" Take the assessment entitled "PhysioEx 26" This is an open book assessment with no time limit. Ashcroft discussion 2 Week 10 10/14 Respiratory Physiology II R F 10/18-19 Fall Break Week 11 10/21 Nerve Physiology I Guyton 28-29 Online Notes Online Lectures Worksheet PhysioEx 22 Check under "assignments" Take the assessment entitled "PhysioEx 26" This is an open book assessment with no time limit. Guyton 31,32 Online Notes Online Lectures Neuroscience Interacvtive Complete the exercise on this web page and take the assessment entitles neuroscience interactive Ashcroft Ch Ashcroft discussion 6 Week 12 10/28 Week 13 11/4 Nerve Physiology II EXAM III Ch 20-23, 27-29 Gastrointestinal Physiology 2 Student presenters Guyton 37,38 Online Notes Online Notes 2 Online Lectures Worksheet Guyton 42-44 Online Notes Online Lectures Worksheet Ashcroft Ch Exam III PhysioEx23 Check under "assignments" Take the assessment entitled "PhysioEx 23" This is an open book assessment with no time limit. 2 Student presenters Guyton 49-53 Endocrinology EXAM 4 Week 14 11/11 M 11/11 Holiday CH 31,32,37,38,42-44 2 Student presenters Online Notes 1 Online Lectures 1 Online Notes 2 notes part 2 A Online Lectures 2 Worksheet 8 Exam IV Guyton 54-56 Week 15 11/18 R F 11/22-23 Holiday Reproductive Physiology Online Lectures 1 Online Lectures 2 Online Lectures 3 Online Lectures 4 Online Lectures 5 Online Lectures 6 PhysioEx 16 Check under "assignments" Take the assessment entitled "PhysioEx 16" This is an open book assessment with no time limit. Ashcroft Ch Week 16 11/25 Review and Final Exam CH49-53, 54-56 Final Exam *** This is a tentative schedule. The text we are using is new, therefore the instructor reserves the right to alter the schedule at any time. It is your responsibility to be in class and check your blackboard page in order to keep pace with any changes made to the schedule or assignments.*** IX. TEACHING STRATEGIES A combination of lecturing, interactive lecturing, laboratory exercises and computer based presentations will be used. XI. Bibliography Books N. A. Campbell and J. B. Reece. (2004) Biology 7 th Edition. Addison Wesley Longman, Inc. Journals Electronic journals and databases may be accessed through the Charles Chestnutt Library or through external links from our blackboard page: http://blackboard.uncfsu.edu/ http://library.uncfsu.edu 9