Erin Baas KNH 413 PUD Case Study Questions: 1. List all the food items that may contribute to GG’s condition and explain why. a. GG’s diet consisted of a lot of fast food, fried food, frozen dinners, coffee, chocolate, and alcohol. Frequently consuming an excessive amount of alcohol causes the lining of the stomach wall to not be able to properly breathe from the irritating effects of the alcohol. Overtime this can lead to gastritis. The caffeine found in coffee and chocolate can increase the stomach acid, which can lead to gastritis. Fast foods contain a lot of salt, which can irritate the stomach lining and also cause gastritis. (http://www.peacehealth.org/xhtml/content/cam/hn-1217004.html#hn-1217004- eatingright) (http://www.the-alcoholism-guide.org/alcoholic-gastritis.html) 2. List any additional oral intake that may have contributed to GG’s condition and explain why. a. GG’s oral intake of tums, aspirin, and chemicals found in the cigarette smoke may have contributed to her condition. The chemical irritants found in cigarettes can damage the lining of the stomach. Taking aspirin frequently like GG does can also cause damage to the lining of the stomach. Tums reduce stomach acidity to relieve any burning symptoms a person might have. However, reducing stomach acidity too often can make it easier for an individual to get an infection. (http://www.healthcentral.com/acid-reflux/guide-154319-75.html?ic=506048) 3. List the non-oral stimulants (physical or psychological stress that could contribute to GG’s condition and what she could do to change them. a. Trying to balance being a single parent, working, going to school, and having to maintain good grades could all be contributing to GG’s condition. Being a single parent isn’t something she can change. However, maybe she could create a better routine with her mother and babysitting. She could also take fewer credit hours in school. This way she isn’t so stressed out with homework, will have more time to spend with her son, and would hopefully not feel the need to drink so often. This would also allow her time to possibly add physical activity into her daily or weekly routine, which could definitely help relieve some of her overall stress. 4. List the symptoms of GG’s gastritis. a. Abdominal pain, burning stomach pain after meals, and indigestion. 5. Was a bland diet necessary? Explain and list the principles of the diet plan that you think GG should follow. a. A bland diet was not necessary, but GG should be educated through nutrition therapy on how she eat more healthfully and what foods she should stay away from so she won’t worsen her condition. She should definitely stay away from any foods or drinks that may increase acid production/irritate the stomach. Foods containing high antioxidant and flavonoid content such as bell peppers, blueberries, cherries, green tea, squash, apples, cranberries, garlic, and onions would serve her body well in not worsening her condition. Foods high in flavonoids can potentially help eliminate H. pylori in the system. Probiotic foods would also serve GG well in that they contain live bacteria cultures that can help to reduce the number of harmful bacteria in the stomach. (http://healthyeating.sfgate.com/ulcer-friendly-foods-3909.html) 6. What is the mechanism of action of the following medications GG is receiving: Carafate, AlternaGel, and Pepcid? a. Carafate: The mechanism is unknown, but is thought to form an ulcer-adherent complex with proteinaceous exudate, such as albumin and fibrinogen, at the ulcer site, protecting it against further acid attack. b. AlternaGel: It is used to treat symptoms of increased stomach acid, such as heartburn, upset stomach, sour stomach, or acid indigestion. c. Pepcid: It decreases the amount of acid the stomach produces. (www.drugs.com) 7. List the nutrient-drug interactions that are associated with these medications. a. Carafate: May reduce the absorption of other drugs. Therefore, other drugs should be taken two hours prior to taking Carafate. b. AlternaGel: Can interfere with the absorption of many other drugs. Shouldn’t take at meal time. c. Pepcid: May interfere with the absorption of other drugs that require acid for adequate absorption. (www.medicinenet.com) 8. What are GG’s IBW and percent of IBW (Appendix A, Tables 7 and 8)? a. IBW = For women 100 lbs for the first 5 feet of height, then add 5 lbs for every inch over 5 feet, or subtract 5 lbs for every inch under 5 feet. IBW = 110 lbs %IBW = actual body weight / usual body weight x 100 = 98 lbs / 110 lbs x 100 %IBW = 89% 9. Estimate her daily energy needs using the harris-benedict equation and appropriate stress factor (Appendix A, Table 17). a. Harris-Benedict Equation = 655 + (9.56 x weight in kg) + (1.85 x height in cm) - (4.68 x age) = 655 + 425.4 + 291.3 - 126.4 = 1,245 kcals Stress factor = 1.5 (active; has ulcer) =1,245 x 1.5 = 1,867 kcals 10. What might be the cause of the LUQ pain along with her usual pain? (Hint: consider the enzymes that are elevated). a. Pain in the left upper quadrant is often seen in individuals with gastritis. Elevated liver enzymes can be caused by GG’s alcohol consumption, which can cause pain. (https://docs.google.com/a/muohio.edu/viewer?a=v&q=cache:gPLRFmOEKCoJ:mededc onnect.com/samplechapters/9781455707720/9781455707720.pdf+&hl=en&gl=us&pid=bl&srci d=ADGEEShXK123BpXE9JfMPjAUTSxtRkvHX0SJBICVURX_pK9_l0AyE12mzx9Cnx7iB8b3TZ kZfmOtAUghye0DvcjCakQ2eVQE_7XcRx6u65srx78w9Y4FD1RLAp69CNuPvPlyT6t0snn6&sig =AHIEtbQO-xP6y-ls_dYM_AOr7DMmMDQefg) 11. In the second set of lab values, glu, BUN, Cr, ser alb, Na, K, Cl, hgb, and hct all dropped. This probably means that GG was: a. bleeding b. eating poorly in the hospital c. dehydrated when the first labs were drawn d. over hydrated when the second set of labs were drawn 12. In the second set of lab values, serum amylase, AST, and ALT all dropped. This probably means that: a. enzymes were elevated due to alcohol b. her medications caused them to drop c. GG was dehydrated with the first labs were drawn d. GG was over hydrated when the second set of labs were drawn 13. Refer to the two lab tables again, and note that two days after admission, GG’s Alk Phos and CPK remained essentially unchanged. Why? a. these enzymes are not affected by alcohol or hydration b. her medications caused them to drop c. dehydrated when the first labs were drawn d. over hydrated when the second set of labs were drawn 14. What diagnostic test(s) (not lab values) indicate(s) that GG has an ulcer? a. GG had an esophagogastroduodenoscopy, which showed she had blood in her stool, gastritis, and an ulcer. She was also tested positive for H. pylori through an endoscopy. 15. Briefly sketch the anatomical position where GG’s ulcer can be found. 16. Define: H2 antagonist: An agent that blocks the action of histamine by competitive binding to the H2 receptor; used to inhibit acid secretion in the treatment of peptic ulcer. Proton pump inhibitor: A group of drugs that reduce the secretion of stomach acid. They act by binding with the enzyme H+, K(+)-ATPase, hydrogen/potassium adenosine triphosphate, which is sometimes referred to as the proton pump. This enzyme causes parietal cells of the stomach lining to produce acid. (http://medical-dictionary.thefreedictionary.com) 17. What is the mechnism of action of the following medications GG is receiving: Nexium, amoxicillin, and clarithromycin? a. Nexium: A proton pump inhibitor that suppresses gastric acid by specific inhibition of H+, K(+)-ATPase in the gastric parietal cell. b. Amoxicillin: Belongs to a class of antibiotics called penicillins. These antibiotics don’t kill bacteria, but they stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. c. Clarithromycin: Prevents bacteria from growing by interfering with their protein synthesis. (www.medilexicon.com) 18. GG was not receiving counsel at the time the major bleeding started. If you had the opportunity to counsel GG just before the bleeding, in what areas would you feel competent to counsel her and in what areas would you refer her to someone else? Investigate the agencies in your area that are available to provide assistance to someone like GG. a. I would definitely want to counsel GG on how she could reduce her symptoms by improving her diet and educating her on what foods/drinks will aggravate her the most and the least. However, I would not feel comfortable aiding her on which medications would be best for her to take. I would recommend she see a physician/doctor when it comes to medications. 19. What is the significance of the dark stools? a. Blood in the stool can come from anywhere along the digestive tract. Dark/black stools usually mean the blood is coming from the upper part of the GI tract. This includes the esophagus, stomach, and the first part of the small intestine. (http://www.nlm.nih.gov/medlineplus/ency/article/003130.htm) 20. Give the pathophysiology for the cause of the following abnormal values: BUN, NH3, and WBC. a. BUN: High BUN levels mean your kidneys aren’t working well. It can also be caused by urinary tract obstruction, congestive heart failure, or gastrointestinal bleeding. b. NH3: Abnormal values of NH3 can be caused by congestive heart failure, GI bleeding, genetic diseases of the urea cycle, hyperthermia, and liver failure. c. WBC: High WBC count is called leukocytosis. This can be caused by anemia, bone marrow tumors, infectious diseases, inflammatory disease, leukemia, severe emotional or physical stress, or tissue damage. (http://www.nlm.nih.gov/medlineplus/) 21. GG was probably dehydrated on admission since she had been drinking. This means that some of her lab values were probably higher/lower (circle one) than indicated. 22. After admission GG received packed cells and IV fluids. How would that affect the next set of lab values. a. This would cause the next set of lab values to be decreased. 23. Define the following terms: Packed cells: A preparation of blood cells separated from liquid plasma, often administered in severe anemia to restore adequate levels of hemoglobin and red blood cells without overloading the vascular system with excess fluids. Abdominal tap: A procedure used to remove fluid from the area between the belly wall and the spine, otherwise known as the abdominal cavity. Perforated ulcer: An ulcer extending through the wall of an organ. Fistula: An abnormal or surgically made passage between a hollow or tubular organ and the body surface, or between two hollow or tubular organs. Exploratory Laparotomy: An incision through any part of the abdominal wall for the purpose of physically examining the contents of the peritoneal cavity. Billroth I: Excision of the pylorus with end to end anastomosis of the upper portion of the stomach and the duodenum. Vagotomy: The surgical cutting of the vagus nerve to reduce acid secretion in the stomach. (http://medical-dictionary.thefreedictionary.com/packed) 24. Sketch Billroth I. 25. Compare a Billroth I to a Billroth II as to anatomical changes as well as dietary changes, if any. a. Billroth I, a partial gastrectomy, is the surgical removal of a section of the stomach, and then reconnects the top half of the stomach to the duodenum. Billroth II, a gastrojejunostomy, removes part of the stomach, and then the top half of the stomach is reconnected to the small bowl. After either of these surgeries, patients will need to eat smaller, more frequent meals while decreasing their oral intake. (Nutrition Therapy & Pathophysiology, page 364) 26. Calculate GG’s energy and protein needs. a. Energy Needs: EER = 354 - 6.91 x age + PA x (9.36 x weight + 726 x height) = 354 - (6.91 x 27) + 1.45 x (9.36 x 44.55) + (726 x 1.57) = 1,911 kcals = 1,900-2,000 kclas/day Protein Needs: = Around 15% = 1950 x .15 = 293 kcals/day from protein 27. List the principles of a postgastrectomy diet and briefly describe the scientific basis for each principle. a. Eat calorie dense foods to maintain body weight. Eat a variety of foods by gradually adding foods to your diet, such as fruits, vegetables, whole grains, protein rich foods, dairy products, etc. Eat small frequent meals to make sure you’re getting the proper nutrition. Therefore, always carry snacks with you and don’t go more than 2-3 hours without eating something. Add more calories whenever possible to, once again, make sure you are maintaining your body weight. Drink nutrient rich beverages that provide a lot of calories. These can be easier to get down than solid foods. Even though you may not be hungry, make sure you eat, because the food and nutrients are what are going to help excel the healing process. (http://www.nostomachforcancer.org/gastric-cancer/life-without-a-stomach/basicprinciples-of-nutrition-after-gastrectomy) 28. Is it possible that GG’s diet will ever change or do you believe she will be on a postgastrectomy diet for the rest of her life? a. Following a postgastrectomy diet at first will be important for GG to help her recover. However, as long as she starts gradually adding in a more healthful range of foods over time, and steers clear from the foods and drinks that were causing her symptoms in the first place, I think she will be able to eat more than just what is recommended. Optional Questions: 29. If GG were hospitalized for an extended period of time and required a tube feeding via duodenum or jejunum, what characteristics would be appropriate for the tube feeding you would use? a. Characteristics: Small frequent feedings, calorie dense foods, variety of foods, high protein, high fat, low CHO, and liquid between meals. 30. Using the table below, compare several of the enteral nutritional supplements that would be appropriate for GG. Prod uct Prod ucer Form Ensur e high protei n Ensur e vanill a ready to drink Ensur e high protei n shake Ensur e Crea my milk choc. ready to drink Cal/ mL 0.97 Nonpro cal/g N Pro (g/L) CHO (g/L) Fat (g/L) Na mg K mg 93:1 12 31 6 290 500 25 23 2.5 280 440 mOs m /kg water Vol to meet RDA in ml g of fiber /L 610 237 0 414 3 Free H2O /L in ml Prod uct Prod ucer Form Ensur e plus Ensur e Butter pecan ready to drink Ensur e Ensur e Ensur e Enliv e Ensur e Cal/ mL Nonpro cal/g N Pro (g/L) CHO (g/L) Fat (g/L) Na mg 1.5 146:1 13 50 11 220 Straw berry ready to drink 1.06 149:1 9 40 6 Apple ready to drink 1.01 7 43 0 K mg mOs m /kg water Vol to meet RDA in ml g of fiber /L 400 680 237 0 200 370 620 237 0 35 35 796 198 0 Free H2O /L in ml