Nutrition Class #1 Tuesday, January 7, 2003 Chapter 1: Nutrition Basics **Table 1-1 Terms (page 5) Body Mass Index - 25 or greater considered overweight and 30 or greater considered obese, can assess health problems for individuals Obesity - BMI greater than 30 Risk Factor - talking about a disease process Kilocalorie - foods and their energy contents (can convert to joules, conversion factor is 4.2 J/cal) Table 1-2 Leading Causes of Death in the United States Most common is heart disease and then cancer 6 Nutritional Components Energy Sources: 1. Proteins 2. Carbohydrates 3. Lipids Structural Features: 4. Vitamins - fat-soluble (tendency to accumulate and become toxic) versus water soluble (involved in chemical processes, alter the rates of reactions) 5. Minerals - non-organic Solvent: 6. Water Calories calorie - energy required to raise 1 gram of water 1 degrees Celsius Calorie (kcal) - energy required to raise 1 kilogram of water 1 degree Celsius Proteins and Carbohydrates 4 cal/gram Lipids 9 cal/gram Alcohol 7 cal/gram Food Label (page 11) Dietary fiber means indigestible carbohydrates Table 1-4 Years When Common American Foods Were Introduced Chart Versus Target Values and Current Estimated Values in the Population Scientific Method Case Control Studies and Double-blind Studies Double-blind standard is as good as it gets when it comes to scientific experiments Situations Regarding Red Flags Red flags - breakthrough, amazing new information, etc. are buzzwords that should make you suspicious Genetics and Nutrition Genetic profile (page 31) will help you determine what risk factors can effect you How to Find Reliable Information on Nutrition (page 23) Lists web sites for valuable information Chapter 2: Introduction to Nutrients Nutrient Density Refers to vitamin and mineral content per Kilocalorie For large nutrient density we want high vitamin and mineral content and low number of kilocalories Energy Density Ratio of kilocalories per gram Of those 3 energy-containing nutrients, lipids have the highest energy density Want to remove the more energy dense foods (lipids) because removing less food from the diet (360 kcal - remove 40 grams of fat or 90 grams of carbohydrates) Table 2-2 (page 42) Dietary Reference Intakes (DRI) Possible to overdose on any of the 6 components of nutrition Recommended Dietary Allowance - want to watch out for Table 2-4 Comparison of Daily Values with the Latest Dries and Other Nutrient Standards Table 2-6 Food Pyramid Guide Base is cereal grains Fruits and vegetable As move towards top fewer and fewer servings Replaced the 4 food groups Other versions available Nutrition Class #2 Tuesday, January 14, 2002 Body Mass Index Ratio of weight to height Calculated by dividing one's weight in pounds by square of one's height in inches, and multiplying by 703. (703 corrects for pounds and inches) Food Pyramid (Page 48) At the bottom of the pyramid are things people should eat more of, and as one progresses to the top, the fewer servings that one is supposed to have Replaced the food groups Various other versions of food pyramids (Page 74) Criticisms of Food Pyramid (Page 51) Other information at Harvard School of Public Health Food Labels Food Exchange System Appendix D Assessment of Calorie Count (Page 514) ***Dietary Assessment Project (Page 70-71) Keep a log of food and activities for a few days (what you eat and how much and activities) (weekends and weekdays) 4-5 Days Chapter 3: Human Physiological Processes Review Organization of the Body Tables 3-3 to 3-6 Are you taking care of your digestive tract? (Page 120) Chapter 4: Metabolism Appendix on chemistry Chapter 5: Carbohydrates Monosaccharides Glucose Fructose Galactose Disaccharides Lactose Fructose Maltose Oligosaccharides Between 3-8 simple sugars Raffinose Stachyose Appear in vegetables, legumes, etc. and are for the most part indigestible Polysaccharides More than 9 simple sugars Digestive Processes of Carbohydrates Glycosidic linkage has to be hydrolyzed Complex Carbohydrates Nutrition Class#3 Tuesday, January 21, 2003 Nutrition Perspective Chapter 3: When Digestive Processes Go Awry Chapter 5: Carbohydrates Monosaccharides Glucose Fructose Galactose Disaccharides Maltose Sucrose Lactose Complex Carbohydrates Dietary Fiber is carbohydrates found in the diet with indigestible glycosidic linkages Soluble vs. Insoluble Does not take into account whether or not a substance is digestible Soluble is gums, pectins, and mucilages Insoluble is celluloses and hemi-celluloses* Bran is largely cellulose with some hemi-cellulose Insoluble Insoluble items pass directly through digestive system Soluble Some soluble items can be digested Microbes in the intestine digest some soluble carbohydrates, and as a result, produce by-products because of the metabolic breakdown Have 1-3 kcal/g Sugar Alcohols vs. Sugar Acids Sugar alcohols will be CH2OH Sugar acids will have carboxylic acid COOH ***Table 5-1 Classification of Dietary Fibers (page 167) Non-carbohydrate Lignins ***Review Carbohydrate Digestion Complex Carbohydrates Mixtures of digestible carbohydrates (starches) and non-digestible carbohydrates (fiber) Uses of Carbohydrates 1. Energy source 2. Glucose properties: Protein sparing indicates that the carbohydrate is used for fuel instead of a protein Ketosis production (acidosis) is using a carbohydrate instead of fatty acid 3. Adding flavor and sweetness Starches have very little sweetness associated with them Role of Fiber 1. Diverticula are small pouches that develop in a person's large intestine Diverticulosis is occurrence of diverticula, usually asymptomatic Diverticulitis is when diverticula become inflamed, symptomatic, and usually arises when food becomes trapped in diverticula 2. Tends to slow food absorption A. Glucose absorption B. Cholesterol absorption* Food moves faster through intestinal tract in a high fiber diet, so food is not absorbed as fast High Fiber Diets and Colon Cancer Requirements of Carbohydrates No RDA Estimated value of total energy spent is 50-75% carbohydrates About 10% of total carbohydrate intake are simple sugars Problems with High-Fiber Diets Phytobezoars are fiber balls that accumulate in the stomach Lactose Intolerance Digestive disorder in which the body fails to produce an enzyme to catalyze hydrolysis of lactose Glycosidic bond is hydrolyzed by microbes in small intestine, which produces gas, etc. Not a food allergy Certain ethnic groups are more likely to develop lactose intolerance Maturity enhances people getting lactose intolerance Diet of Simple Sugars Has a low nutrient density ("empty calories") Examples: soft drinks, candy, etc. Fat Free Foods Bland taste initially until simple sugars are added so people are eating high carbohydrates Tooth Decay Diet high in simple sugars and carbohydrates can lead to tooth decay (dental caries) Glycemic Index www.diabetesnet.com When you ingest a food, your blood sugar increases and then returns to normal in about 2-2 1/2 hours Glucose tolerance curve Nutrition Class #4 Tuesday, January 28, 2003 *Read Perspectives at end of each chapter Food Sweeteners High fructose corn syrup is corn syrup with added fructose to obtain a high level of sweetness High fructose corn syrup is a lot cheaper than cane sugar Alternative sweeteners - Nutrasweet (aspartame) are sweeter so use less of it and therefore calorie content is reduced in the diet Sugar alcohols include sorbitol and is used in substances that are labeled "sugar-free" Sugar alcohols do not produce tooth decay as often as other carbohydrates Sugar alcohols do have a calorie count Glycerol is another type of sugar alcohol that comes from dihydroxy acetone or glyceraldehyde Chapter 6: Lipids Saturated Fatty Acids On each end is a methyl group and carboxylate group Unsaturated Fatty Acids Also have a methyl group on one end and carboxylate group on the other end Also have one or more double bonds in the middle of the chain Short Chain Fatty Acid Less than 6 carbon Medium Chain Fatty Acid Between 6-10 carbons Long Chain Fatty Acid More than 12 carbons Fatty Acids Almost always have even numbers of carbon Synthesized from acetyl CoA Delta Notation Starts at carboxyl end and names the fatty acid Nutrition Notation Starts at methyl group and names the fatty acid Denotes starting at methyl group by starting with "omega" Omega-3 and Omega-6 Fatty Acids Essential fatty acids Prostaglandins and other metabolites are synthesized at the expense of these fatty acids Have to accumulate these omega-3 and omega-6 fatty acids from dietary intake because they cannot be made in the body Linolenic is an omega-3 fatty acid Linoleic is an omega-6 fatty acid Prevalent in the normal diet It is possible to overdose on essential fatty acids (blood clotting time is elongated and platelet formation is impacted which makes you more susceptible to hemorrhaging) Triglycerides Triacylglycerols is a more descriptive name Energy content Triacylglycerols Non-polar Lipids Depot fat Energy storage Membrane Lipids Phosphatides - diacylglycerol (diglycerides) Sphingolipids Polar lipid bilayer Cholesterol Water-insoluble Precursor for bile salts, steroid hormones, etc. Can be a membrane component Synthesized from the acetyl CoA Fat Digestion *Review in text Cholecystokinin (CCK) Hormone involved in lipid digestion Stimulates the release of bile Lipid Transport LDL, HDL, and VLDL are lipoproteins (mixed micelles with cholesterol esters) *Refer to a chemistry book Satiety Fat in one's diet gives the sensation that you have eaten enough Put enough fat in your diet so that you will not be eating soon after you have just finished a meal Gastric Inhibitory Protein (GIP) Tend to slow down the release of food into the lumen of the small intestine Trans Fatty Acids In a cis double bond there is a bend in the configuration Less of a bend in a trans configuration at a double bond More cis fatty acids than trans fatty acids To extend shelf life of a lipid make the oil more saturated by removing the double bond with hydrogen gas and a platinum catalyst This process is carried out at relatively high temperatures Unless you hydrogenate the lipids completely, then you get some trans double bonds Hydrogenating some lipids completely causes them to be hard as brick Partially hydrogenated means that some of the double bonds are still present Major occurrence in trans fatty acids are in margarines, potato chips, etc. (processed foods) Want to produce foods that have long shelf lives and right consistency Food Additives Added to extend shelf life BHA and BHT Vitamin E is a fat-soluble antioxidant Retard spoilage Nutrition Class #5 Tuesday, February 4, 2003 **Look at Table page 206 Cholesterol Water-insoluble Lipid Typically found in animal lipid sources, rarely found in plants Higher the fat content, the higher the bile salts the body makes so more cholesterol present in the diet Has no metabolic consequences but a precursor for bile salts and material for cell membranes Fat Replacements Having fat in diet with minimal detriments Fats provide flavors, textures to foods, and satiety Olestra is an engineered fat that is indigestible Lipids Most energy dense foods **Table 2-9 Definitions for Comparative and Absolute Nutrient Claims on Food Labels Blood Lipids Too many LDLs causes problems High amounts of HDLs helps Chapter 7: Proteins Essential Amino Acids Required by the organism and the organism cannot synthesize them Nonessential Amino Acids Can be synthesized by the organism Why do we need protein in our diet? 1. Supply essential amino acids 2. Transport mechanism for nitrogen 3. Fuel source Dietary Sources for Proteins 1. Animal proteins are complete proteins except for gelatin Gelatin is an incomplete protein that is a structural component for collagen 2. Plant proteins are incomplete proteins, which means that they do not contain all of the amino acids Complementary Proteins One plant protein does not contain amount of essential amino acids that the body needs so combine with complete protein and body will obtain amount that is needed Table 7-2 Protein Synthesis Protein Turnover As a routine basis, the body is continuously hydrolyzing and synthesizing proteins As proteins are hydrolyzed they make amino acids, and as proteins are synthesized they consume amino acids Protein thru hydrolysis to make amino acids Amino acid thru synthesis to make proteins Amino acids are used for carbohydrate synthesis, acid-base balance, and specific metabolites When use amino acids that are essential, have to supply them from diet so that appropriate proteins can be made Use 300-400 grams of protein per day Amino acids contain carbon that can be used as fuel (calorie burn is about 4 calories/gram) Nitrogen Balance Measure of nitrogen intake and nitrogen output Modes of Nitrogen Loss 1. Urea is formed in the liver in response to variable nitrogen intake Need to expose nitrogen because variable intake, cannot store it, and it is toxic to the body Use nitrogen for acid-base balance RDA for Protein Based on nitrogen intake Want a slight overage so that you will end up with more nitrogen Need about 0.8 grams/kilogram of normal body weight Different levels for different ages On average amino acids are about 16% nitrogen by weight Nutrition Class #6 Tuesday, February 11, 2003 Evaluation of Protein Quality Page 280-281 Biological Value Protein Efficiency Ratio Chemical Score of Protein Protein Digestibility Corrected Amino Acid Score Protein Energy Malnutrition Kwashiorkor Marasmus Nutrition Perspective: Vegetarian Diets Chapter 8: Alcohol Energy Content for Ethyl Alcohol 7 calories/gram Alcohol Metabolism From carbohydrates Alcohol dehydrogenase pathway - 95% of alcohol consumption will be metabolized via this method Will generate reducing agents Hepatic process Microsomal ethanol oxidizing system Fortified Wines Grain alcohol that has been distilled and then extra alcohol added to it Speed of Metabolism Males metabolize alcohol faster than females Benefits of Alcohol Use In the past it was used in place of water because dirty water or water not available Detriments of Alcohol Use Fetal alcohol syndrome Fetal alcohol effect Binge Drinking vs. Alcohol Dependency Binge drinking is an episodic situation Alcohol dependency is when a person becomes sick without alcohol and has to be professionally detoxified, cannot usually go more than 8-10 hours without alcohol CAGE Questionnaire C - Cut down A - Annoyed by questions G - guilty about drinking E - Eye-opener Nutrition Class #7 Tuesday, March 5, 2003 Fat-Soluble Vitamins 4 vitamins (A, D, E, and K) E and K discovered recently Hydrocarbon tail A lot of benzene rings Beta-carotene - provitamin A, found in bright orange and yellow vegetables Retinals are halves of the beta-carotenes Trans-retinal is more stable Vitamin D is a cholesterol derivative Absorption from digestive tract dependent on amount of fat in one's diet Chylomicrons Liver is first organ site for vitamin breakdown Vitamins can be stored and can overdose on them Vitamin A 2 Versions - carotenoids (precursors - Beta-carotene) and retinols Function is regarding vision Carotenoids and Retinols Carotenoids found in plants and vegetables (orange, yellow, and dark green vegetables) Beta-carotene will processed into "Retinoids" - active form, retinol (alcohol), retinal (aldehyde), and retinoic acid (acid) Liver will store carotenoids and retinoids Carotenoids are absorbed via the lymphatic systems Retinoids are absorbed via the portal system Transport via lipoproteins Role of Retinoids Visual process Rhodopsin is a combination of the 9- or 11-cis-retinal Cis-retinal and opsin react to make rhodopsin Energy from light will transfer rhodopsin to prelurmirhodopsin (trans-retinal) Trans-retinal is active agent that will induce a hyperpolarization Trans-retinal will be transferred back to cis-retinal by isomerase, will cost energy Trans-retinal will be changed by NADH to trans-retinol (active agent) Cis-retinal will be changed by NADH to cis-retinol (active agent) Both of these processes require energy Cell Differentiation Vitamin A also associated with cell differentiation Used in various types of skin disorders Food Sources for Vitamin A Carotenoids come from plant sources Retinoids come from animal sources (liver, fish, eggs, etc.) Best source of vitamin A is polar bear liver IU vs. RAE Varies with gender and age 900 RAE for males and 700 RAE for females between the ages of 19 and 70+ Possible to overdose on fat-soluble vitamins Toxicity Acute, chronic, or tetragonic Tetragonic amounts produce birth defects Toxicity is more related to retinoids **Look at symptomatology of Vitamin A toxicity Major problem is night-blindness Vitamin D Vitamin D is formed when there is a bond breakage in cholesterol Most come from fortified foods Not many natural food sources Active form is 1,25-Dihydroxycholecalciferol Sunlight impact has to be relatively intense (usually get enough sun light in the summer or where it is relatively warm year-round) Sunlight impact is a function of latitude and also is related to skin color RDA is a sliding scale for Vitamin D (less than 50 years is 5 micrograms per day, between 50-70 years is 10 micrograms per day, and more than 70 years is 15 micrograms per day) Can store Vitamin D for several weeks Function of Vitamin D Play a role in maintaining plasma calcium levels Calcium reserves are the bones Problems associated with Ricketts Hard to reverse disease in adults Another problem is osteoporosis Also helps regulate phosphate concentrations *Know difference between Ricketts and osteomalacia About 5 times the average intake o Vitamin D can cause toxicity Nutrition Class #8 Tuesday, March 11, 2003 Vitamin E Tocopherols (different forms, 8 versions that have to do with stereochemistry, alpha, beta, gamma, etc.) Classified as an antioxidant, dressed up reducing agent Free radical is an agent that has an unpaired electron, as a result they are high energy agents (example: hydrogen peroxide) R reacted with energy (and sometimes a metal ion) yields an R group with free electron This compound reacts with oxygen to yield a peroxide Peroxide reacts with another R group and yields? (process continues on and on) Tocopherol will react with R group with free electron or peroxide Antioxidant will interrupt a reaction Glutathione (GSH) is tripeptide made up of 3 amino acids (glutamate, cystine, and glycine); it is a reducing agent Sources are vegetable oils, whole grains, etc. About 22 natural IUs and 33 artificial IUs Toxicity is rare, hard to overdose, no known disease associated with it Vitamin K Phylloquinone Absorbed lymphatic system Cofactor Reaction that it engineers is associated with blood clotting factors Known as the "clotting factor" Deficiency is blood hemorrhaging Water-Soluble Vitamins Vitamins B and C Absorbed via the hepatic portal system Tendency not to collect in fatty tissues so not very toxic Tend to flush them out regularly so need to supplement often Vitamin B Tend to be lost in cooking, absorbed in water (cook item as quickly as possible) **Refer to Table on pages 402-403 (summary of B vitamins) Function as coenzymes Thiamin (B1) 1. Activate "acyl" functions 2. Involved in transketolase reaction (pentose pathway) Disease is Beri Beri (cannot produce acetyl CoA so cannot produce acetylcholine), have congestive heart failure, skeletal muscle wasting, etc. Usually seen in alcoholics Active form is TPP (thiamine pyrophosphate) Riboflavin and Niacin Redox cofactors in dehydrogenase reactions Riboflavin (FAD, FMN) - TCA, Beta-oxidation, ETS Niacin (NAD, NADP) Disease process associated with Niacin is Pellagra Whole grains are major food sources Pantothenate Involved in coenzyme A Usually found in acyl functions Extremely difficult to have get a deficiency Biotin Involved in carboxylation reactions (pyruvate to generate oxaloacetate) (odd carbon fatty acids and branched chain amino acids) Hard to have get a biotin deficiency Pyridoxine Used in transamination reactions (utilized in amino acid reactions and expelling nitrogen in urea) Associated with PMS and carpal tunnel syndrome Folate Folate (folic acid) is in series of reactions that transfer methyl groups (1-carbon) (uracil to thiamine, homocysteine to methionine, norepinephrine to epinephrine, etc.) Deficiency can cause megaloblastic anemia and neural tube defects Cobalamin (B-12) Final absorption in ilium "Intrinsic factor" is glycoprotein synthesized in stomach Cobalamin transported by intrinsic factor Involved in homocysteine to methionine and norepinephrine to epinephrine reactions Disease process is pernicious anemia Available in animal products Vegans and elderly individuals are at risk for deficiency Nutrition Class #9 Tuesday, March 18, 2003 Class Projects Copper Wearing a bracelet is useless in obtaining copper into your diet Trace element for animals and humans Used for synthesis of ATP Absorbed in stomach and most in small intestine Involved in absorption, metabolism of iron Activate lysyl oxidase Aneurysms is cause of deficiency Also associated with Parkinson's disease because increased copper in CSF Increased perception of red and green colors Deficiencies are associated with high blood pressure, reduction in strength of arterial walls, myelin defects, etc. Leukopenia is also associated with copper deficiency Zinc interferes with absorption of copper (be careful with zinc supplements) Normal RDA is .8 to 1.5 mg 200(+) mg indicate copper toxicity Extreme toxicity can lead to suicide 2 diseases: Wilson's disease and ? Foods that contain copper are leafy green vegetables, liver, nuts, etc. Creatine Occurs naturally in foods Natural forms are found primarily in meat, fish, and other animal products Stored as high energy molecule used in production of ATP Creatinine is a waste product excreted in urine Important when there is a transition from rest to intense explosive exercise High carbohydrate diets are required to maintain insulin necessary for muscle creatine transport Causes water retention (approx. 1.5 to 2.0 kg) Aerobic endurance activities are not positively influenced by creatine Effects renal system (should not use if already have renal disease) Many professional athletes are using it Many college coaches are trying to stop their athletes from using it If used in excessive amounts during competition can be associated with "doping" What are essential fatty acids? Can only be supplied by the diet Body cannot produce a carbon-carbon double-bond Linolenic Acid and linoleic acid Vital parts of body structures, immune system function, visual function, eicosanoids (prostaglandins, prostacyclin, etc.) Omega-3 reduces heart arrhythmias, thrombosis, decrease TAG levels, reduce rate of plaque, etc. (found in plant oils, mayonnaise, salad dressing, whole grains, vegetables) Omega-6 is found in fatty fish (salmon, tuna) and plant oils Can overdose in essential fatty acids, need to balance both because imbalance can lead to problems clotting or not clotting blood Nutrition Class #10 Tuesday, March 25, 2003 Alternative Nutrition for Huntington's Chorea 3 stages: 1. Patient still can be independent, depression, slow tremors, etc. 2. Partially dependent, increased irritability and mood swings, trouble swallowing 3. Degeneration in the brain, total dependency, walk only with assistance, severe tremors, tube feeding Need alternative nutrition because of diabetic-like metabolism (trouble digesting glucose) Test was on 2 groups of mice Nutrition diets lead to slower progression of symptoms, less body weight, better digestion of glucose Disease has no cure Fast Food Diet Benefits: convenient, predictable, cheap, tastes good, and fast Risks: high calorie, fat, cholesterol, sugar, sodium, and low nutrient Calories for men: 2700/day For women: 2000/day Fat 30% of total diet Double Whopper with cheese with large fries is the worst Domino's pizza is lower in fat but high in sodium Vitamin and Nutrient Losses as a Result of Medications Most Common: antacids, antibiotics, antihistamines, etc. Antacids: lose calcium (tooth decay), phosphorous, and folic acid (anemia) Antibiotics: B vitamins, K, magnesium, iron, B6, and zinc (weak immunity) Bronchodilators: potassium and B6 (sleep problem) Female Hormones: ERT and HRT, oral contraceptives (folic acid, magnesium, B3, B6) Thyroid Medications: iron depleting (anemia) Case study: multivitamins did not help healthy individuals, but helps immune compromised individuals Hollywood 48 Hour Diet Special formula of all natural fruits and purees, vitamins, etc. Jamie Kable is the inventor Weight loss of up to 10 pounds or more Decrease in cravings for "killer" foods Disrupts regular food intake, cleansing digestive system, and activating body's internal fat-burning surface Does not disrupt the diet but you do not eat To keep weight off transition slowly back to healthy diet Food Allergies and Food Intolerance See handout Food allergy is an immune reaction to food Most common: milk, eggs, wheat, peanuts, tree nuts, fish, shell fish, soy In children, most common are milk, eggs, and peanuts Ingestion of food causes large production of IgEs Contaminated meat has many of the same reactions as food allergies Food intolerance produced by yellow dye number 5, MSG, and sulphites Celiac disease is a permanent adverse reaction to gluten Wheat allergy is an IgE mediated response Russian Air-Force Diet See handout Created in Russia during the Cold War Vitamin D, E, and folate are low Caloric intake is low Nutrition Class #11 Tuesday, April 1, 2003 Phosphate Loading **See Handout Popular for endurance athletes Phosphate is major component for ATP Typically get a lot of phosphate in our diet daily RDA 800-1200mg per day Research varies from improved endurance to no correlation Not illegal No apparent effects except for GI problems No one knows about long term effects, only possible problem is phosphate might interfere with calcium absorption Blood Type Diet 60% of adults are overweight 1/5 of Americans are obese CDC reports that diabetes has increased by 33% since 1990 Developed by Dr. Peter D'Adamo Chemical reaction occurs between blood and foods you eat. Reaction caused by Lectins, abundant and diverse proteins found in foods. Blood Type A: typically docile, more at risk for cancer, diabetes, etc., should eat mostly vegetarian Type O: should eat lots of proteins and less carbohydrates, thrive on doing a lot of exercise Type B: Opposite of Type A, weaker immune systems, eat balanced diet, fits food pyramid best Type AB: weaker immune systems, lots of vegetables, mixed diet No evidence that suggests that the diet works, no known research Lipids Improve memory Provide energy Improve cell's response Reduce allergies Hormonal balancing 2 essentials: omega-3 and omega-6 (most Americans get more omega-6 in their diets) Get omega-3 flax, walnut, fish, etc. (fish oil is best source) Get omega-6 from olive oil Major killers: cancer, cardiovascular disease, and diabetes Overweight and under nourished (recommend 21 as BMI, BMI of 25 is usually associated with health related diseases) Need omega-3 to control weight because improves sensitivity of insulin receptors, etc. Low fat leads to poor health (brain is 60% lipid) low omega-3 is associated with depression Use cod oil in cold weather because contains vitamin D Recommended ratio of 1:1 of omega-3 and omega-6 Manganese Trace mineral Metal is reactive chemically Found mostly in bones but also in liver, pancreas, glands, and active metabolic organs Co-enzyme for citric acid cycle Important for digestion and utilization of foods, supports immune system, etc. Low levels associated with fatigue, depression, joint dislocations, etc. High levels associated with migraine, PMS, muscle tremors Mostly in nuts and whole grains but also in leafy greens, legumes, coffee beans, etc. No RDA, recommended value is 2.5-5mg per day Toxic levels are around 50mg per day Benefits of Olive Oil Most commonly eaten monounsaturated oil Types: differences in acidity virgin (4%), extra virgin (less than 1%), and light does not mean less calories 77% monounsaturated fat Reduces the oxidation of LDL's and maintains HDL's Cholesterol buster Good for your heart Breast cancer prevention Colon protection Loves your skin (helps prevent skin cancer) Helps your joints (can help prevent rheumatoid arthritis) Mediterranean Diet: bread, pasta, rice, fruit and vegetables, use olive oil as fat, high in fat content Olive Oil Diet: Lindsey McLean, "detox diet", eat what you want, drink olive oil straight (recommends juice chaser after) Fats and Alzheimer's Mental deterioration manifested by loss of memory, ability to calculate, etc. Beta amyloid develops in brain No known cause Vaccine currently being tested Dietary fats help prevent but some may increase the chances of disease More saturated fats the greater the risk Should eat polyunsaturated fats Need to start now because after a person gets the disease nothing helps Antioxidants do not help Coral Calcium 50 times more absorbable Eat sand which contains coral calcium Discovered by people from Japan who used to feed their cows and chickens this sand and discovered that more eggs and milk were produced so started to include this sand in their diet May play a role in body pH Choosing Not Cheating Dr. Howard Shapiro's Picture Perfect Weight Loss Perspective on what you can eat Shows pictures in the book to show you what you should choose to eat Thiamin (Vitamin B-1) Carbohydrate metabolism, nerve impulses, oxygen metabolism, etc. Mainly absorbed in jejunum TPP is active form Most values for males and females are relatively the same Pork, watermelon, mushrooms, sunflower seeds, etc. Benefits are depression, muscle tenderness, sciatica, etc. Diseases are Beriberi (2 types are wet and dry), Wernicke-Korsakoff syndrome (associated with alcohol) Swank MS Diet By Dr. Swank in 1950 Associated the Multiple Sclerosis (disease of central nervous system) In females more than males 4 ways to categorize MS Low fat, high oil diet Eating less fat slows down the deterioration of myelin sheath People can live a long time with no complications when they are on this diet Started diet in Canada Fat provides the most energy (9 calories per gram) High oil because need essential fatty acids which are necessary for function of nervous system Vitamin supplements should compliment diet (Vitamin A and D, cod oil etc.) Folic Acid (B9) Water soluble vitamin Composed of pteridine, para-aminobenzoic acid, and one molecule of glutamate Needed for DNA replication, needed for synthesis of Adenine and Guanine, and neurotransmitters Associated with megaloblastic anemia and neural tube defects (anencephaly and spina bifida) Neural tube defects are common in China and Japan Spina bifida is bulges in neural tube Level of spina bifida determines amount of disability Best sources are liver, fortified foods, legumes, whole grains, and vegetables Try to eat foods that are not processes as much RDA is 400 micrograms for women during child-bearing years Benefits of Flaxseed Oil Rich source of essential fatty acids Abundant source of lignan Symptoms are aching joints, constipation, cracked nails, forgetfulness, immune weakness, etc. Omega-6 and omega-3 balance important to keep cell membranes fluid, provide "good" prostaglandins, improve blood flow, etc. Flaxseed oil is associated with decreased heart disease, cancer, etc. Lignan, found in seed hull, are antiviral, antifungal, and antibacterial properties Grapefruit Diet 2 1/2 months lose 52 pounds Grapefruit or juice starts burning process Lacks sufficient amounts of iron, calcium, and vitamins Zinc Essential mineral found in almost every cell Stimulates activity of enzymes Needed for wound healing and growth, DNA replication, etc. Best source is oysters, also found in poultry and meats, etc. Absorbed in small intestine RDA 3-14 mg Deficiency causes growth retardation, hair loss, diarrhea, etc. Lower amount for infants and pregnant women Toxicity is 40mg/dayu, causes decrease in HDL, interferes with copper metals, etc. Wound healing: increase T-lymphocytes, fight infection, etc. More research needed on effects on common cold