Pasteur Institute - Ho Chi Minh City Training Center INTERNATIONAL WORKSHOP OUTBREAK INVESTIGATION AND ACUTE RESPONSE 4-8 NOVEMBER 2013, HO CHI MINH CITY, VIETNAM PROGRAM AMBASSADE DE FRANCE Délégation régionale de Coopération INDEX Foreword ……………………………… 3 Opening Address ……………………………… 4 Organizing Committee ……………………………… 5 Faculty ……………………………… 5 Participants ……………………………… 6 Program ……………………………… 8 2 Foreword Infectious disease is the single biggest cause of death worldwide. New infectious agents, such as the recent novel coronavirus in the Arab Peninsula, and new strains of avian influenza in China, continually emerge and require new investigations. Effective control and prevention of disease outbreaks depend on early detection, rapid on-site investigation and timely and appropriate interventions. In line with the regional training needs in the Asian-Pacific Region, the International Network of Pasteur Institutes in South-East Asia, in close partnership with the Australian National University and the support of the Regional Scientific Cooperation Service of France (SCAC), is organizing an international workshop on “Outbreak Investigation and Acute Response”. This workshop will allow participants to acquire the skills to choose the appropriate analytical study design during an outbreak investigation, develop questionnaires and draw conclusions that guide public health actions, communicate findings of an outbreak investigation for various audiences and conduct similar training in their own institutions or countries. The course is specifically designed for health personnel from countries in South East Asia involved in surveillance activities and outbreak investigation. The workshop will be organized in the International Training Center of the Pasteur Institute in Ho Chi Minh City, which was inaugurated in 2011. Our overarching goal is to establish the foundation of a top training program for epidemiologists working in research and public health in the region, in order to strengthen that ability to react to acute infectious threats. 3 Opening Address of Mr. Fabrice MAURIES Consul General of France in Ho Chi Minh City I am particularly pleased to be at the opening of this international workshop that marks yet another significant initiative during the Année de la France au Vietnam. It seems particularly appropriate that the Pasteur Institute of HCMC is involved in collaboration with Institut Pasteur International Network in this celebratory year, as this is where it all began for the Pasteur Network more than 120 years ago, with the foundation of the first Pasteur Institute outside of France. What makes the Pasteur Network unique is the sharing of common missions, values and culture of excellence and solidarity in research, teaching and public health. This is workshop illustrates these characteristics. An international team of epidemiologists from Australia and Singapore complementing local expertise, an international group of trainees from all countries in SEA gather here to discuss new approaches developed in public health surveillance and operational research. In our society information plays an ever prominent role and a rapid, effective investigation in response to outbreaks is essential to draw conclusions that will guide public health actions and to communicate findings for various audiences. The aim of all training programs in not only to teach a small number of health personnel from countries in South East Asia involved in surveillance activities and outbreak investigation, but also, and more importantly, to give them the skills to conduct similar training in their institutions or countries. This is the long-lasting effect of a successful program that will benefit society at large. The Pasteur Network has a strong focus on infectious diseases, which are the single biggest cause of death worldwide. New infectious agents, such as the recent novel coronavirus in the Arab Peninsula, and new strains of avian influenza in China, continually emerge and require new investigations. Effective control and prevention of disease outbreaks depend on early detection, rapid on-site investigation and timely and appropriate interventions. This is why the international workshop “Outbreak Investigation and Acute Response” is timely and in line with the national and regional priorities of the public health sector. I understand that it is the second year in a row that an international workshop in epidemiology is organized at the Pasteur Institute of Ho Chi Minh City together with the Pasteur International Network and the support of the French Scientific Cooperation Program in the region. It is my hope that this will be the foundation of a world-class training program for epidemiologists working in research and public health in the region, in order to strengthen that ability to react to acute infectious threats. Let me conclude with a warm welcome to all trainees and many thanks to the Teaching Teams for your effort and dedication. 4 Organizing Committee ROBERTO BRUZZONE NGHIA PHAN HKU-Pasteur Research Pole School of Public Health The University of Hong Kong, Hong Kong SAR Email: bruzzone@hku.hk International Training Center Pasteur Institute of Ho Chi Minh City Vietnam phan.tu.nghia@gmail.com Faculty HOANG QUOC CUONG STEPHANIE DAVIS Department of Epidemiology Pasteur Institute of Ho Chi Minh City Vietnam cuonghqpasteur@gmail.com National Centre for Epidemiology & Population Health Australian National University Australia Stephanie.Davis@anu.edu.au DO VAN DUNG DAVID HARLEY University of Medicine and Pharmacy Ho Chi Minh City Vietnam dovandzung@gmail.com National Centre for Epidemiology & Population Health Australian National University Australia David.Harley@anu.edu.au ALDEN HENDERSON VU THỊ QUE HUONG DPHSWD Center for Disease Control and Prevention Atlanta, USA akh0@cdc.gov Department of Microbiology and Immunology Pasteur Institute of Ho Chi Minh City Vietnam huongpasteur@hotmail.com ANDREW LOVER LUONG CHAN QUANG Saw Swee Hock School of Public Health National University Singapore Singapore andrew_arnold_lover@nuhs.edu.sg Department of Epidemiology Pasteur Institute of Ho Chi Minh City Vietnam lcq3372@yahoo.com 5 Participants CHUM Channimol DO Lien Anh Ha US Naval Medical Research Unit 2 Phnom Penh, Cambodia chumnimol@yahoo.com Oxford University Clinical Research Unit Ho Chi Minh City, Vietnam hadla@oucru.org DOAN NGOC Minh Quan INDRA Jaya Pasteur Institute of Ho Chi Minh City Vietnam hunk0706@yahoo.com Ministry of Health of Indonesia Jakharta, Indonesia jayaindra@yahoo.com KHATTINGNAVONG Phonepadith KHENG Sereisophea Institut Pasteur du Laos Vientiane, Lao PDR phonepadithk@gmail.com US Naval Medical Research Unit 2 Phnom Penh, Cambodia Sereisophea.Kheng@namru2.org.kh KHINE Wai Wai Oo Khuu Van Nghia Mahidol University Bangkok, Thailand khinewaioo@gmail.com Pasteur Institute of Ho Chi Minh City Vietnam khuu.nghia@gmail.com KYAW Win Mar LAO Malayvanh Tan Tock Seng Hospital Singapore mar_kyaw_win@ttsh.com.sg Institut Pasteur du Laos Vientiane, Lao PDR malayvanh_Lao@yahoo.com Laura Merson LEUANGVILAY Phetdavanh Oxford University Clinical Research Unit Ho Chi Minh City, Vietnam lmerson@oucru.org World Health Organization Vientiane, Lao PDR sunn263@hotmail.com LUU NGUYEN Thang LUY Malen National Institute of Hygiene and Epidemiology Hanoi, Vietnam luuthangnihe@gmail.com US Naval Medical Research Unit 2 Phnom Penh, Cambodia maienluy@yahoo.com MANUN Kazi Taib NGUYEN Le Manh Hung International Centre for Diarrhoeal Disease Research Dhaka, Bangladesh taib@icddrb.org Institute of Hygiene and Epidemiology Tay Nguyen, Vietnam lehungnguyen80@yahoo.com NGUYEN Thanh Chung NGUYEN Thi Bich Ngoc National Institute of Hygiene and Epidemiology Hanoi, Vietnam bsnguyenthanhchung@gmail.com Pasteur Institute of Ho Chi Minh City Vietnam bnsapphire@gmail.com 6 NGUYEN QUOC Huy PICHIT Pin Pasteur Institute of Ho Chi Minh City Vietnam bsnguyenquochuy@gmail.com US Naval Medical Research Unit 2 Phnom Penh, Cambodia Pin.pichit@gmail.com SOE AUNG May SONTISIRIKIT Sarinthorn Uniersity of Medicine1 Yangon, Myanmar Maysoeag2010@gmail.com Ministry of Public Health Bangkok, Thailand mambow2005@gmail.com SRIDHAR Revathi SUBIDO, Maria Tricia National University Health System Singapore revathi_sridhar@nuhs.edu.sg Research Institute for Tropical Medicine Muntinlupa, Philippines tricia_subido@yahoo.com THAO Phan Thi Thanh TRAN Thi Thu Nga Institute of Hygiene and Epidemiology Tay Nguyen, Vietnam Phan_thao25@yahoo.com Pasteur Institute of Ho Chi Minh City Vietnam thunga_tranthi@yahoo.com WIGNJADIPUTRO Ira ZANARATH Phanoula Ministry of Health of Indonesia Jakarta, Indonesia sin_ik_1999@yahoo.com World Health Organization Vientiane, Lao PDR zanarathp@wpro.who.int 7 Program 4 November 2013 8:00 – 8:30 1. Opening ceremony Tran Thi Giang Huong Head of the Department of International Cooperation, Ministry of Health, Vietnam Phan Trong Lan Pasteur Institute of Ho Chi Minh City, Vietnam Roberto Bruzzone HKU – Pasteur Research Pole, Hong Kong SAR Fabrice Mauriès Consul General of France in Ho Chi Minh City, Vietnam 8:30 – 9:00 2. Trainees’ pre-test 9:00 –9:45 3. Outbreak investigation: Rationale and terminology Andrew Lover National University Singapore, Singapore 9:45 – 10:00 Break 10:00 – 11:00 4. Epidemiologic steps in outbreak investigation Stephanie Davis Australian National University, Australia 11:00 – 12:00 5. Introduction to case study 1 David Harley Australian National University, Australia 12:00 – 13:30 Lunch 13:30 – 15:00 6. Case study 1: Focus on outbreak detection and basic response, including developing a case definition Stephanie Davis, David Harley, Andrew Lover, Hoang Quoc Cuong, Luong Chan Quang 15:00 – 15:15 Break 15:15 – 17:00 6. Case study 1: Focus on outbreak detection and basic response, including developing a case definition Stephanie Davis, David Harley, Andrew Lover, Hoang Quoc Cuong, Luong Chan Quang 17:00 – 17:15 Break 17:15 – 18:30 7. Trainees’ self-presentations 8 5 November 2013 8:00 – 8:45 8. Detect and confirm outbreak Andrew Lover National University Singapore, Singapore 8:45 –9:45 9. Operational issues in outbreak investigation Do Van Dung University of Medicine and Pharmacy in Ho Chi Minh City, Vietnam 9:45 – 10:00 Break 10:00 – 11:00 10. Case definition and conducting case finding David Harley Australian National University, Australia 11:00 – 12:00 11. Epidemiologic study design David Harley Australian National University, Australia 12:00 – 13:30 Lunch & Group Photo 13:30 – 15:00 12. Case study 2: Using a cohort design Stephanie Davis, David Harley, Andrew Lover, Hoang Quoc Cuong, Luong Chan Quang 15:00 – 15:15 Break 15:15 – 17:00 12. Case study 2: Using a cohort design Stephanie Davis, David Harley, Andrew Lover, Hoang Quoc Cuong, Luong Chan Quang 17:00 – 17:15 Break 17:15 – 18:30 13. Trainees’ self-presentations 9 6 November 2013 7:00 – 13:00 14. Field study at Thu Duc Preventive Medicine Center Transfer to Thu Duc PMC by car (4x16 seats) Introduction to outbreak investigation and reporting of communicable diseases at Thu Duc PMC Trainees are divided into 4 groups and visit 4 wards to investigate cases of HFMD or Dengue under the supervision of PMC officers Debriefing on filed study Thu Duc PMC Transfer back to PI-HCMC Teaching Team 13:00 – 14:30 Lunch 14:30 – 15:30 15. Develop and test hypothesis: hypothesis generation using case studies and introduction to statistical testing David Harley Australian National University, Australia 15:30 – 15:45 Break 15:45 – 17:00 16. Role of laboratory in outbreak investigation Vu Thi Que Huong Pasteur Institute of Ho Chi Minh City, Vietnam 17:00 – 17:15 Break 17:15 – 18:30 17. Trainees’ self-presentations 10 7 November 2013 8:00 – 9:30 18. Preparation of an outbreak report 90min Do Van Dung University of Medicine and Pharmacy in Ho Chi Minh City, Vietnam 9:30 –9:45 Break 9:45 – 10:45 19. Introduction to risk assessment and risk communication Do Van Dung University of Medicine and Pharmacy in Ho Chi Minh City, Vietnam 10:45 – 12:00 20. Exercise on risk assessment Do Van Dung University of Medicine and Pharmacy in Ho Chi Minh City, Vietnam 12:00 – 13:30 Lunch 13:30 – 14:30 21. Preparation of study questionnaire 45min Stephanie Davis Australian National University, Australia 14:30 – 14:45 Break 14:45 – 17:00 22. Epi-info exercise (Version 7) Stephanie Davis Australian National University, Australia 17:00 – 17:15 Break 17:15 – 18:30 23. Trainees’ self-presentations 11 8 November 2013 8:00 – 8:45 24. Environmental and other additional studies Alden Henderson US CDC 8:45 –9:45 25. Control and response measures Alden Henderson US CDC 9:45 – 10:00 Break 10:00 – 11:00 26. Common pitfalls in outbreak investigations Alden Henderson US CDC 11:00 – 12:00 27. Preparation of public health recommendation Alden Henderson US CDC 12:00 – 13:30 Lunch 13:30 – 14:30 28. Post-test 14:30 – 15:30 29. Course evaluation 15:30 – 15:45 30. Closing remarks Teaching Team 19:00 Dinner 12