Chapter 1 – History of Microbiology
Note Outline
Early Years
Antoni van Leeuwenhoek (1632-1723)
Carolus Linnaeus (1707-1778)
Eukaryotic1. Fungi
2. Protozoa
movements:
1. Pseudopodia2. Cilia3. Flagella3. Algae
Prokaryotes-
4. Bacteria
5. Archae
Others
6. parasitic worms- why?
7. Viruses-
Why was there a delay from Leeuwenhoek?
Does Spontaneous Generation (abiogenesis) exist?
1. Francesco Redi (1626 – 1697)
2. John Turberville Needham (1713 – 1781)
3. Lazzaro Spallanzani (1729 – 1799) *reported results in 1799
Conclusions:
1.
2.
3.
objections4. Pasteur (1822 – 1895)
Biogenesis =
How is this different from abiogenesis?
Scientific Method
1.
2.
3.
4.
control groupsWhat causes Fermentation?
Pasteur
Pasteurization* Father of Microbiology
Biotechnology =
Buchner (1860 – 1917)
-fermentation doesn’t require living cells. Why?
What causes Disease?
1857- Germ theory of Disease Robert Koch- etiology (study of causation of disease)
Advances: (see p. 15)
Koch's Postulates
1.
2.
3.
4.
How can we prevent Infection and Disease?
1. Ignaz Semmelweis
2. Joseph Lister
3. Florence Nightingale
4. John Snow
5. Edward Jenner
6. Paul Ehrlich
Today
Molecular biology -
Recombinant DNA –
Gene therapy -