THE URINARY SYSTEM The urinary or excretory system functions to control the volume and composition of the blood. It filters waste products from the blood and expels them from the body in the form of urine. The Kidneys The kidneys are two bean shaped organs found just above the waist on either side of the vertebral column. Blood passes through the kidneys and waste products and excess fluid is taken from it. The cleaned blood then returns to the circulatory system. Two kidneys are situated retroperitoneal on either side of the lumbar region of the spine. They consist of a cortex region and an inner medulla. The depression on the medial border is called the hilum through which blood vessels and nerves pass. The functions of the kidneys are: removal of urea from blood maintenance of correct balance of water, salts and acids in body fluids, e.g. salts such as sodium and potassium. Some acids are known as electrolytes. Electrolytes are necessary for correct functioning of muscles and nerve cells. The kidneys form urine and eliminate it from the body. The endocrine function of the kidneys is to secrete renin a substance important in the control of blood pressure, erythropoietin, a hormone that regulates production of erythrocytes (red blood cells) and an active form of Vitamin D (which aids in the absorption of calcium) from the intestines. Nephrons are the filtration units of the kidney. Each nephron contains a cluster of blood capillaries called glomeruli (singular is glomerulus). This is where the blood is actually filtered. The renal cortex is the rind or outer area of the kidney, the middle is called renal medulla and the inner section is called the renal pelvis. The renal pelvis is the central collecting region of the kidney at the wide upper end of the ureter. Ureters Once urine is filtered through the nephrons, it drains into the renal pelvis. From the renal pelvis, urine is transported away from the kidneys in tubes called ureters. The ureters join the urinary bladder. There are two (2) ureters which are muscular tubes, lined with mucous membrane. Their function is to convey urine from the kidneys to the urinary bladder. Urinary Bladder The urinary bladder is a hollow muscular sac, which serves as a temporary reservoir for urine. At its base is a triangular space the trigone, where the ureters enter and the urethra leads out. When urine is expelled from the bladder it is called micturition, voiding or urination. The bladder can also be referred to as a vesicle. URINARY SYSTEM PAGE 1 OF 6 Urethra The urethra is a small tube through which urine is moved from the bladder to the exterior of the body. The female urethra is about 4cm long while the male urethra is about 20cm long. The urinary meatus is the term given to the external opening of the urethra. Urine Urine is composed of 95% water; the rest is made up of waste products. Word Parts Albin AlbumAlbumin Azot Cyst -Gram Hydr/o Lith Combining form Meaning Albin/o White White Albumin (protein) Urea Bladder (sac) X-ray, image, tracing, recording Water Stone Kidney (nephron- functioning part of the kidney. Basic unit of kidney, comprising a glomerulus, Bowmans's capsule etc. Deficiency/few/little Many/much Falling/displacement Refers to the space inside the kidney, renal pelvis (pyle portal vein) Kidney Trigone of the bladder Urine Urinary canal, ureter (kidney to bladder) Tube through which urine leaves the body from the bladder, urethra (bladder to outside) Urine, the excretory or waste product of the kidneys Bladder (or sac/blister) Albumin/o Azot/l Cyst/o Hydr/o Lith/o Nephr Nephr/o Olig/o Poly-ptosis Olig/o Pyel Pyel/o Ren Trigon Ur Ureter Ren/o Trigon/o Ur/o, -uria Ureter/o Urethr Urethr/o Urin Vesic Urin/a, urin/o, urin/i Vesic/o Activity 1 Write the meaning of the following words: 1. renogram 2. nephrolithotomy 3. glomerulitis 4. pyelonephrosis URINARY SYSTEM PAGE 2 OF 6 5. vesicocele 6. urethrostenosis 7. urinalysis 8. oliguria 9. dysuria 10. lithotripsy Activity 2 Build words which mean: 1. Surgical fixation of a kidney 2. Condition of pain in a kidney 3. Surgical repair of the renal pelvis 4. x-ray picture of the renal pelvis 5. Instrument to view the bladder 6. Specialist who studies the urinary tract 7. Abnormal urination at night Diseases and disorders of the urinary system The urinary system has two major types of disorders that affect it. One is when the filtration of urine from the blood is disturbed, the other is when the flow of urine either from the kidneys to the bladder, or from the bladder to the outside of the body, becomes blocked. If the filtration of blood does not take place, then the blood quickly becomes toxic. If the patient is not treated they will die. This condition is commonly known as renal failure. Interventions to save the patient can be artificial filtration of the blood by a process called dialysis; another approach may be a kidney transplant. Renal failure is caused by damage to the kidneys, which can include infections, trauma, cancer, or damage caused by toxic (poisonous) agents, such as certain drugs. Blockages in the ureters, bladder and urethra can be caused by inflammation from infections, cancers and tumours, and mineral deposits that form stones or calculi – these are known as kidney stones or renal calculi, and sometimes they have to be surgically removed. If a blockage occurs in the renal tract then the urine begins to build up. If the blockage is not removed, the urine will quickly backup into the kidneys and cause damage. URINARY SYSTEM PAGE 3 OF 6 Other disorders involve the composition of urine, the amount of urine that is passed from the body, and the ability of the body to control the bladder. Diseases and disorders include: Disease Albuminuria Definition Presence of protein (albumin) in the urine Anuria Cystitis (cyst/o means bladder) Dysuria An inability to pass urine, or an absence of urine Enuresis Incontinence at night, bed wetting Frequency Passing of urine more than every two hours Haematuria Blood in the urine Incontinence Involuntary passing of urine Nephritis Inflammation of the kidney Nephrolithiasis Stones in the kidneys (calculi) (abnormal condition of) Nocturia Abnormal urination during the night Polyuria Pyelonephritis Passing large amounts of urine, of frequent urination Presence of above normal levels of protein in the urine, usually indicating a urinary tract infection Inflammation of the kidney caused by bacterial infection Renal calculi A stone in the urinary tract Retention Inability to pass urine Urethritis Inflammation of the urethra Urinalysis A test to analyse the composition of the urine Urinary alkaliniser A medication to reduce acid content of urine (e.g. Ural) A general term meaning an infection in the ureters, bladder and/or urethra Proteinuria Urinary Tract Infection (UTI) URINARY SYSTEM Inflammation of the bladder Painful or difficult urination PAGE 4 OF 6 Activity 3 Read the following paragraph and rewrite it using lay terms. A 26 year old woman presented with a two day history of severe dysuria. She has been passing small amounts of urine with increasing frequency. A urinalysis was performed with the results showing moderate proteinuria and haematuria. There was no indication of nephritis or kidney involvement on physical examination, and a diagnosis of cystitis was made. The patient was prescribed a urinary alkaliniser and antibiotics. _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ Abbreviations: ARF BUN CRF CSU HD HNPU IVP KUB MSU TUR (TURP) UA, Ua UTI Acute renal failure Blood, urea, nitrogen Chronic renal failure Catheter specimen urine Haemodialysis Has not passed urine Intravenous pyelogram Kidneys, ureters, bladder Mid stream urine Transurethral resection (of the prostate) urine analysis (urinalysis) Urinary tract infection Procedures: Haemodialysis Pyelogram (intravenous) Pyelogram (antegrade) Pyelogram (retrograde or ascending) URINARY SYSTEM Technique of removing waste materials or poisons from the blood using the principle of dialysis Injection of contrast medium via vein into blood stream which then runs through kidneys and x-ray is taken (intra – meaning inside, ven/o – meaning vein) The dye is injected into the renal pelvis before it leaves the kidney. (ante – meaning before/in front; grad – meaning take steps/to go). The dye is injected through the skin via a percutaneous catheter. Insertion of cystoscope into bladder, fine tube passed through cystoscope up ureter to kidney, contrast medium injected into the urine within the pelvis, x-ray taken (against the flow) (retro – latin, means backwards) PAGE 5 OF 6 Urinary system Write the combining forms on the dotted lines using the following word components. More than one component may relate to the one position. Cyst/o Glomerul/o Nephr/o Pyel/o Ureter/o Urethr/o Urin/o Vesic/o URINARY SYSTEM Ren/o Page 6 of 6