Exam 2 Study Guide What is a tissue? What are the 4 main types of tissues, give the functions, structure of each. Cell Junctions. Define each, give function Tight Junctions Adherens Junctions Desmosomes Hemidesmosomes Gap Junctions What is the basic structure of epithelial tissue? (Slide 7 and 8) What is the function of epithelial system? What are the two main types of epithelial tissue and where might you find them? What are the 3 main shapes of epithelial tissue? What are the 3 arrangements of epithelial tissue? Give some examples of each of the above and where you might find them. What are the 2 main types of glands? Give examples of each. Endocrine Exocrine What is the difference between merocrine, apocrine, holocrine glands? What are the 2 main shapes of exocrine glands? What are the different arrangement of exocrine glands? What is the basic structure of connective tissue? What are the functions of connective tissue? What are the cells of connective tissue, what are their functions, and give an example of where you might find them. Fibroblasts Macrophage Plasma Cells Mast Cells Adipocytes White blood cells What are the components of the extracellular matrix of connective tissue, define and tell me where you might find them Ground Substance Fibers Collagen Elastic Reticular What is mesenchyme? What are the different types of mature connective tissue, give structure, where I might find them? Loose Connective Areolar Adipose Reticular Dense Connective Regular Irregular Elastic Cartilage Hyaline Fibrocartilage Elastic What is the difference between appositional growth and interstitial growth? Bone Compact Spongy Blood What is a mucous membrane? (Function, structure, location) What is a serous membrane? (Function, structure, location) What is a cutaneous membrane? (Function, structure, location) What is a synovial membrane? (Function, structure, location) What is the function of muscular tissue? What is the structure of muscle tissue? Skeletal/striated Smooth Cardiac Where would I find each of these types of muscle, and tell me whether it is under conscience or unconscious control What is the function of nervous tissue? What is the structure of nervous tissue? Where would I find nervous tissue? What are the two main layers of the integumentary system? What are the accessory structures found in your integumentary system? What are the functions of your integumentary system? What is the study of the integumentary system called? What type of epithelial cells make up the epidermis? What are the four main types of cells found in the epidermis, give function of each, which are the most numerous? Keratinocytes Melanocytes Langerhans Cells Merkel Cells What is thin skin, what sets it apart from thick skin, and where would you find it? What is thick skin, what sets it apart from thin skin, and where would you find it? Name the layers of the epidermis from deep to superficial, give me the structure of each and whether it is dead or alive Stratum Basale Stratum Spinosum Stratum Granulosum Stratum Lucidum Stratum Corneum Know the diagram on slide 13 Describe to me how the epidermis grows. What are some epidermal conditions? What type of connective tissue makes up the dermis? What are the cells of the dermis? Fibroblasts Macrophages Adipocytes What other structures are found in the dermis? What are the layers of the dermis from superficial to deep, describe the structure of each. Papillary Reticular What layer of your dermis is responsible for making fingerprints? What are your skin pigments? Which pigment is responsible for protection from UV light? What is the precursor molecule to melanin? What are some abnormal conditions in skin color, and what are they caused by? Freckles Liver Spots Mole Albinism Vitiligo Where is hair present and NOT present? What is the cellular structure of hair? Where does the growth of hair begin? Is your hair mainly alive or dead? Know the diagram on slide 22 What are the other accessory structures associated with hair? Know the diagram on slide 24 What are the three stages of hair growth, describe each, and approximately how long each takes. Growth Phase Regression Phase Resting Phase What are the three types of hair, and where would you find each? What types of cells are the basis of the structure for glands? What types of glands are located in your skin, endocrine or exocrine? What are the 3 types of glands in your skin, give the structure, what the secretion is called, function, location. Sebaceous Sudoriferous Eccrine Apocrine Ceruminous What is the cellular structure of nails? What are the parts of a nail? What are the functions of nails? Explain two ways the skin can provide a thermoregulatory function. List five ways the skin serves in protecting the body. What are cutaneous sensations? What is the skins role in excretion? What substances can be excreted? What substances can be absorbed by the skin? Why? How does the skin serve to synthesize Vitamin D? Describe what a deep wound is, and the steps in deep wound healing. Inflammatory Phase Migratory Phase Proliferative Phase Maturation Phase What type of tissue is bone? What are the functions of the skeletal system? What are the parts of a long bone, be able to label diagram on slide 4 What is the matrix of bone tissue? What are the cells of bone tissue, what is the function of each? Osteogenic Cells Osteoblasts Osteocytes Osteoclasts Describe compact bone and spongey bone, what are the main differences between the two? What is the function unit of compact bone? What is the functional unit of spongey bone? What are the arteries/veins that supply blood/nutrition to the bones, carry away wastes, where are each located? Periosteal Artery Nutrient Artery Metaphyseal Artery Epiphyseal Arteries What is bone formation called? What are the four types of bone formation, when and why does each occur? Initial bone formation Intramembranous Ossification Endochondral Ossification Growth Length (include information about the growth plate) Width What is the difference between interstitial growth and appositional growth? What are some hormonally induced growth problems? Describe each. Remodeling (function?) Bone Resorption Bone Deposition What are some conditions that can occur when remodeling bone? What are some hormones that can affect growth/remodeling of bone? Repair What is a fracture? What is the difference between a stress fracture and a compound fracture? What are the steps in repairing bone? What is bones role in calcium homeostasis? What hormones control calcium homeostasis? What cells are responsible to fix if there is too much calcium in the blood? What cells are responsible to fix if there is not enough calcium in the blood? At what times during life do the following events occur? Deposition > Resorption Deposition = Resorption Deposition < Resorption What are the different types of bones, describe each, and give some examples where you would find them. Long Short Flat Irregular Sesamoid Sutural Given some bone names, please tell me if they are in the axial or appendicular skeleton. What is a joint? What is the structure based on? What are the types of joints, give type of movement, structures, examples of each? Fibrous Suture Syndesmoses Interosseus Membranes Cartilaginous Synchondroses Symphyses Synovial Please describe the structure of the synovial joint Plane Hinge Pivot Condyloid Saddle Ball-and-Socket What are the 3 types of muscle tissue, give basic structure and example of each Striated Smooth Cardiac What are the functions of muscles? What are the properties of muscles? What is the structure of skeletal muscle? Epimysium Perimysium Endomysium Tendon Aponeurosis Be able to label the diagram on slide 7 with the above terms What is the microscopic structure of skeletal muscle, give description/function of each? How many nuclei? Sarcolemma Transverse (T) tubules Sarcoplasm Myofibrils Sarcoplasmic Reticulum (SR) Terminal Cisterns Myofilaments Thin Filament Thick Filament Sarcomere Be able to label the diagram on slide 9 with the above terms What are: Z-Discs A Band I Band H Zone M Line What are your muscle proteins. Be able to give me the function of the following: Actin Myosin Troponin Tropmyosin What is the basic tenet of muscle contraction? What are the detailed steps of muscle contraction from motor neuron impulse to passive relaxation? Slides 14-19 What variables does the force of a contraction depend on? What is a twitch contraction? What is wave summation? What is unfused tetanus? What is fused tetanus? What is motor neuron recruitment? What is muscle tone? What is the difference between and isotonic and isometric contraction? What are the three ways muscles make ATP? Which is the fastest? Which yields the most ATP? How do you classify muscle fibers? What are the 3 types of muscle fibers? Compare and contrast in terms of speed of contraction, means of ATP generation, amount of myoglobin, amount of mitochondria, and what types of contractions are possible. Slow Oxidative Fibers Fast Oxidative-Glycolytic Fibers Fast Glycolytic Fibers Compare the amount of SO/FO fibers in a natural athlete. What is the structure of cardiac muscle? Does cardiac muscle have a longer or shorter contraction that skeletal muscle? Why? What is smooth muscle, describe the structure? What are the two types of smooth muscle, and where would you find them? Visceral Multiunit Do the contractions of smooth muscle last longer or shorter than skeletal muscle, why? Can mature cardiac or skeletal muscles divide? How do cardiac/skeletal muscle cells repair themselves? Can smooth muscles regenerate? How? What type of tissue is muscle derived from? What are some selected disorders of tissues, skeletal system, muscular system and skin?