2
STUDY GUIDE
1. Atoms and Elements
a.
Write the terms that match the phrases in the spaces at the right.
1) Smallest unit of an element.
Atom
____________________________________________
2) Positively charged subatomic particle.
Proton
____________________________________________
3) Negatively charged subatomic particle.
Electron
____________________________________________
4) Subatomic particle with no charge.
Neutron
____________________________________________
5) Substance that cannot be broken down into
Element
____________________________________________
any simpler substance.
6) Atoms of the same element, with different
numbers of neutrons.
____________________________________________
Isotopes
____________________________________________
Oxygen
7) Most abundant element in the body.
b. Label the atom shown by placing the number of the component in the space by the label, then, provide the responses to the phrases below.
c 1) Nonvalence electrons
_____
a 2) Nucleus
_____
a
b 3) Valence electron(s)
_____
12p
12n
b
c
4) Atomic number of this atom.
____________________________________________
12
5) Atomic weight of this atom.
____________________________________________
24
6) Number of electrons needed to complete its
outer shell.
6____________________________________________
7) Type of chemical bond that is likely to join
this atom to another atom.
____________________________________________
Ionic
8) Symbol of this atom.
c.
____________________________________________
Mg
Diagram an atom of these elements.
Oxygen
Nitrogen
8p
8n
7p
7n
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2. Molecules and Compounds
a.
Write the terms that match the phrases in the spaces at the right.
1) Composed of two elements combined in
a fixed ratio.
____________________________________________
Compound
2) Smallest unit of a compound.
____________________________________________
Molecule
3) Number of chlorine atoms in CaCl2.
2____________________________________________
4) Chemical bond resulting from the donation
____________________________________________
Ionic
of electron(s) from one atom to another.
5) Chemical bond resulting from the sharing of
valence electrons by two atoms.
____________________________________________
Covalent
6) An atom with a net electrical charge.
____________________________________________
Ion
7) The attractive force between a slightly positive
H atom and a slightly negative O or N atom.
____________________________________________
Hydrogen
bond
____________________________________________
Covalent
8) Chemical bonds forming organic molecules.
9) Electrons in the outer shell.
____________________________________________
Valence
electrons
b. Indicate the kinds and numbers of atoms in a glucose molecule (C6H12O6).
Kinds of Atoms
c.
Numbers of Atoms
______________________________________________
Carbon
6
______________________________________________
______________________________________________
Hydrogen
12
______________________________________________
______________________________________________
Oxygen
6
______________________________________________
Identify the pH values as acid (A) or base (B). Circle the pH with the highest concentration of H.
A
A
_____pH
6.8
_____pH
7.4
_____pH
9.5
_____pH
3.7
_____pH
2.8
A
B
B
3. Compounds Composing the Human Body
a.
Identify the following compounds as either organic (O) or inorganic (I).
I NaCl
_____
_____
O Lipids
I CaPO4
_____
O Nucleic acids
_____
_____
I Salts
O C6H12O6
_____
O Proteins
_____
_____
I Most acids
O CH4
_____
I Most bases
_____
_____
O Carbohydrates
I CO2
_____
O Amino acids
_____
_____
O Steroids
O Monosaccharides
_____
O Fatty acids
_____
_____
O Glycerol
O Nucleotides
_____
b. Write the terms that match the phrases in the spaces at the right.
1) Most abundant compound in the body.
____________________________________________
Water
2) Substances dissolved in a liquid.
____________________________________________
Solute

3) A compound that releases H .
____________________________________________
Acid
4) Splitting of ionic compounds into ions.
____________________________________________
Ionization (dissociation)

5) A measure of the H concentration in a solution.
____________________________________________
pH
6) Chemicals that keep the pH of a solution
____________________________________________
Buffers
relatively constant.
7) Class of compounds formed of many simple
sugars joined together.
____________________________________________
Carbohydrates
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8) Type of reaction that joins two glucose
Synthesis
____________________________________________
Glycogen
____________________________________________
molecules to form maltose.
9) Storage form of carbohydrates in the body.
Triglycerides (fat)
____________________________________________
10) Composed of three fatty acids and one glycerol.
11) Composed of two fatty acids and a phosphate
group joined to one glycerol.
____________________________________________
Phospholipids
12) Type of fat whose fatty acids contain no
____________________________________________
Saturated fat
carbon–carbon double bonds.
13) Compound used to store excess energy reserves.
____________________________________________
Triglycerides (fat)
14) Class of lipids that includes sex hormones.
____________________________________________
Steroids
15) Class of compounds formed of 50 to thousands
of amino acids.
____________________________________________
Proteins
16) Chemical bonds that determine the
three-dimensional shape of proteins.
____________________________________________
Hydrogen bonds
17) Bonds joining amino acids together in proteins.
____________________________________________
Peptide bonds
18) A single-stranded nucleic acid that is involved
in protein synthesis.
____________________________________________
RNA
19) Building units of nucleic acids.
____________________________________________
Nucleotides
20) Steroid that tends to plug arteries when
in excess.
____________________________________________
Cholesterol
21) Sugar in DNA molecules.
____________________________________________
Deoxyribose
22) Primary carbohydrate fuel for cells.
____________________________________________
Glucose
23) Building units of proteins.
____________________________________________
Amino
acids
24) Water compartment containing 65% of water
____________________________________________
Intracellular
fluid
in the body.
25) Molecule releasing energy to power chemical
reactions within cells.
____________________________________________
ATP
26) Double-stranded nucleic acid.
____________________________________________
DNA
27) Molecules catalyzing chemical reactions in
cells.
____________________________________________
Enzymes
28) Type of reaction breaking a large molecule
into smaller molecules.
____________________________________________
Decomposition
29) Molecule controlling protein synthesis in cells.
____________________________________________
DNA
30) Element whose atoms form the backbone of
organic molecules.
c.
____________________________________________
Carbon
Match the four classes of organic compounds with the listed substances.
1) Carbohydrates
2) Lipids
3) Proteins
4) Nucleic acids
3 Amino acids
_____
4 Nucleotides
_____
_____
3 Enzymes
2 Steroids
_____
1 Monosaccharides
_____
_____
4 RNA
1 Glycogen
_____
2 Triglycerides
_____
_____
4 DNA
2 Cholesterol
_____
1 Starch
_____
_____
2 Fatty acids
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d. Label the parts of the small portion of an RNA molecule shown and draw a line around one
nucleotide.
3 Nitrogen bases
_____
1 Ribose sugars
_____
2 Phosphate groups
_____
3
1
e.
2
Show the interaction of ADP, ATP, P, and energy in the formation and breakdown of ATP by placing
the numbers of the responses in the correct spaces provided.


1) ADP
3) Energy from cellular respiration P
2) ATP
4) Energy released for cellular work  P
2
3
4
1
f.
Explain the importance of the shape of an enzyme. _____________________________________________
The enzyme’s active site must fit onto the substrate
_____________________________________________________________________________________________
in order for the enzyme to catalyze a reaction.
g.
How does a change in pH change the shape of and inactivate an enzyme? _________________________
A pH change disrupts the hy_____________________________________________________________________________________________
drogen bonding between amino acids composing an enzyme, changing the shape of the enzyme.
4. Clinical Applications
a. Why does a diet high in saturated fats increase the risk of coronary heart disease? Saturated
______________
fats
______________________________________________________________________________________________________
are more likely to be converted into cholesterol than unsaturated fats. Excess cholesterol forms
______________________________________________________________________________________________________
plaques in coronary arteries reducing the blood supply to the heart.
______________________________________________________________________________________________________
b. A patient in a coma is brought to the emergency room. A blood test shows that he has severe hypoglycemia (abnormally low blood glucose) and acidosis. Treatment is begun immediately to increase both blood sugar and pH.
1) Why is a normal level of blood glucose important? _______________________________________
Glucose is the primary energy supply used
______________________________________________________________________________________
by cells in cellular respiration.
2) Why is severe acidosis a problem? ______________________________________________________
A change in pH may inactivate vital enzymes.
______________________________________________________________________________________
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