CV:The Cardiac Cycle Phsl 6051 Feb. 15, 2008 Lisa Carney Anderson ander350@umn.edu 612-625-5644 Reading Assignment • Chapter 12: 373-378 Objectives • Discuss pressure gradients that lead to the operation of the heart valves • Discuss the mechanical and electrical events of the cardiac cycle during diastole and systole using Figure 12-20 • Predict the point within the cardiac cycle when one could hear a murmur for each valve Figure 12-7 Valves Valve Operation • Passive structures opening and closing according to surrounding pressure • EX- Tricuspid valve Pressure RA > RV OPEN Pressure RV > RA CLOSED Cardiac Cycle • Two major division of cardiac cycle – Systole – Diastole • Four smaller divisions of cardiac cycle – – – – Isovolumetric contraction Ejection Isovolumetric relaxation Filling Figure 12-19a Systole Fig 12-19b Diastole NEVER • • • • NEVER Are all four valves open! They can all be closed Two open/Two closed BUT! Never are they all four open! Figure 12-20 Cardiac Cycle Question • Which of the four divisions of the cardiac cycle begins with the first heart sound? – – – – A. B. C. D. Ejection. Filling. Isovolumetric contraction. Isovolumetric relaxation. Valve defects Fig 12-22 Question • If the mitral valve is stenotic, when will you hear the murmur? – A. Diastole – B. Systole Fig 12-21 Ventricular vs. Arterial Case study • Roger Crockett, a 68-year-old man with a 40-pack-year smoking history and recent complaints of angina (sub-sternal chest pressure) upon exercising, goes to you, his primary care provider. • (Copyright ©2000 The McGraw-Hill Companies) Critical thinking • While listening to his heart with a stethoscope, you notice a high-pitched, blowing, systolic murmur, heard best directly under the left nipple. A review of Roger's medical records shows no prior history of a heart murmur. What is causing this new murmur? • Is the cause of the murmur in any way related to his heart attack? Explain. Questions? Next Lecture Regulation of Cardiac Output