Sharp
Chapter 14: Mendel and the Gene Idea
14.1 Mendel used the scientific approach to identify two laws of inheritance
 Mendel’s Experimental, Quantitative Approach- character, traits, crosspollination, true-breeding, self-pollinate, hybridization, P generation, F1
generation, F2 generation
 The Law of Segregation- dominant trait, recessive trait, heritable factor,
gene, alternative versions of genes account for variations in inherited
characters, alleles, locus, for each character an organism inherits two
alleles, dominant allele determines appearance (while) recessive allele
has no noticeable effect on appearance, law of segregation, Punnett
square, homozygous, heterozygous, phenotype, genotype, testcross
 The Law of Independent Assortment- monohybrid cross, dihybrid cross,
law of independent assortment, linked genes
Concept Check 2
14.2 The Laws of probability govern Mendelian inheritance
 The Multiplication and Addition Rules Applied to Monohybrid Crossesmultiplication rule, rule of addition
 Solving Complex Genetics Problems with the Rules of Probability
Concept Check 1,2,3
14.3 Inheritance patterns are often more complex than predicted by simple Mendelian
genetics
 Extending Mendelian Genetics for a Single Gene- complete dominance,
codominance, incomplete dominance
 The Relation Between Dominace and Phenotype- a dominant allele does
not subdue a recessive allele
 Frequency of Dominant Alleles- polydactyl, multiple alleles, pleiotropy,
cystic fibrosis, sickle-cell disease, ABO blood group, IA, IB, i
 Extending Mendelian Genetics for Two or More Genes- epistasis,
quantitative characters, polygenic inheritance
 Nature and Nurture: The Environmental Impact on Phenotype- norm of
reaction, multifactorial,
 Integrating a Mendelian View of Heredity and Variation
Concept Check 1,2
Sharp
14.4 Many human traits follow Mendelian patterns of inheritance
 Pedigree Analysis- pedigree
 Recessively Inherited Disorders- carriers, cystic fibrosis, sickle-cell
disease, consanguine matings
 Dominantly Inherited Disorders- achondroplasia, Huntington’s Disease
 Multifactorial Disorders- multifactorial diseases, heart disease, cancer
 Genetic Testing and Counseling- genetic counselors, amniocentesis,
chorionic villus sampling (CVS), in utero
Concept Check 1,2
Testing Your Knowledge 1-17