Processes of Evolution & Genetics Part 1 Learning Objectives: Part 1 1. Demonstrate an understanding of the historical context in which the theory of evolution was originally formed. 2. Demonstrate an understanding of the theory of evolution and the mechanisms of evolution (especially natural selection) 1. Illustrate this understanding through accurate examples 3. Demonstrate an understanding of the mechanisms that underpin inheritance 1. 2. Describe the link between meiosis and Mendelian genetics Explain how Mendelian inheritance patterns can be modified by linkage & sex chromosomes What is Evolution? • Evolution • __________________ • More specifically: • _________________________________ • What does this definition imply? • Populations ___________, not _____________ • It is __________ • What does this mean? What is Evolution? • Evidence that supports the theory of evolution ____________ • ___________ • ________________ ___________ History of Evolutionary Thought Pre-Darwinian Views • ___________ • _____________________ • Earth is ___________ • _________________(4th century) • _________________of organisms from _________ • _____________________ – closer to ________, greater excellence History of Evolutionary Thought • Precursors to the Theory of Evolution • 5 scholars & their contributions Scholars Charles Lyell Brief Summary of Contribution ‘Principles of Geology’ Uniformitarianism Georges Curvier Saw potential of fossils Catastrophism ‘Father of Taxonomy’ ‘An Essay on the Principles of Population’ Inheritance of Acquired Characteristics Transformational evolution Carolus Linnaeus Thomas Malthus Jean-Baptiste Lamarck History of Evolutionary Thought Charles Lyell (1797-1875) • __________________ • ___________________ • Natural processes _________________________ ________________________________________ • Processes are _________________ • Used to reconstruct ____________________ History of Evolutionary Thought Georges Cuvier • _______________ • How does this idea compare to the concept of stasis? • __________________ • ___________event(s) explain • ____________________ • ____________________ • 1796 paper: Mammoth Remains History of Evolutionary Thought Carolus Linnaeus (1707-1778) • Developed __________________ • Species, genus, class, order, kingdom • Binomial Nomenclature • Genus, species • Example: ___________ History of Evolutionary Thought Thomas Malthus (1776-1834) • “An Essay on the Principles of Population” • _____________________________ • Inspired Darwin • ____________________________ ______________________________ History of Evolutionary Thought Jean-Baptiste Lamarck (1744-1829) • Inheritance of __________________ • ______________________________ • Central idea: When life forms reproduce, _____ ______________________________________ • Changed in form over time for _________________ • Now know: Mechanism is _____________ • Offspring _________________________ Development of Natural Selection Charles Darwin • Using Mathus’ essay and Lyell’s uniformitarian view, combined with his own observations on biological variation and sexual reproduction, _______________ • • • • _________________ _________________ _________________ _________________ Development of Natural Selection Charles Darwin • _______________________ • Natural selection explains _________________ • Shifts in traits in response to ___________________ • Descent ___________________ • Similar traits indicate _________________ • ______________________ • ________________________ • Affects individual’s _____________________________ • Transmitted ___________________________________ Development of Natural Selection Key Points to Natural Selection • _________________________ • Traits are ___________________to the next generation • Over ______________, successful ______________ • Later generations ____________________________ • All species can ____________________________ Development of Natural Selection Key Points to Natural Selection • Competition for ___________ (___________) • Individuals with ________________________ ______________________________________ • _________________________________ • Determines whether a _____________________ • ________________________ Development of Natural Selection ____________________acts on __________ ________, but it is the _____________ that they are a part of that actually ___________. Describing Traits • Aptation • Adaptation • Exaptation Natural Selection in Action Panda’s thumb • Lamarckian explanation • ____________________ • Darwinian explanation • _____________________ • _____________________________ • Ability to ________________________________ • “The panda's "thumb" is not, __________________. It is constructed from a bone called the radial sesamoid, normally a small component of the wrist,” (Gould, 1980) Natural Selection in Action MENDEL’S DISCOVERIES Early Thoughts on Heredity • Ancient Greek Influence • Predominant belief characteristic of offspring resulted from the blending of parental traits • _______________________________ • How hereditary information was transmitted was unknown until the late 19th and early 20th century Mendel’s Experiments Mendelian Trait: _______________________ Dominance and Recessiveness • Dominant Trait: governed by an ____________ _____________________ • Dominant alleles can _____________________ • Recessive Trait: a trait ___________________ • What’s an allele? • _________________________________________ Dominance and Recessiveness • How to recognize? • Uppercase letters refer to dominant alleles (i.e. T) • Lowercase letters refer to recessive alleles (i.e. t) • These symbols are used to represent the genotype • Genotype: __________________________ • Phenotype: ____________________________ Mendel’s Experiments What happened when Mendel crossed the parent generations? • Parent (TT) (tall) x Parent (tt) (short) • Resulting F1 generation • __________ • Genotype: ________ • Phenotype: _______ Mendel’s Experiments What happened when Mendel crossed F1 hybrids? • Expression that was absent from F1 reappeared • Resulting F2 generation: • Genotype: ____________ • Phenotype: ___________ Terms to Know • Homozygous: ______________________________ • Example: Parent Generation • All tall plants were homozygous for the dominant allele (tall) = TT • All short plants were homozygous for the recessive allele (short) = tt Terms to Know • Heterozygous: _______________________________ • Example: F1 Generation • Offspring of F1 generation were Tt had inherited one allele from each parent plant • Possessing two different alleles at the same locus Mendel’s Principles of Inheritance 1. Principle of Segregation • Genes ___________ (i.e. RR, or Rr, or rr) • During _____________________________ • During fertilization, the genes are reunited and the ______________________________ • Thus, ____________________________ Explanation for Principle #1 Mendel’s Principles of Inheritance 2. Principle of Independent Assortment • Distribution of _________________________ ___________________________________ • ______________________________________ Explanation of Principle #2 Mendelian Inheritance in Humans • Mendelian traits (or discrete/simple traits) • Describes a characteristic influenced only at one locus • Examples: • 1. • 2. • 3. • 4. • 5.