AP Biology Ch 14

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AP BIOLOGY CHAPTER 14 MENDEL AND THE GENE IDEA
NAME__________________________________________________
I. MENDEL USED THE SCIENTIFIC APPROACH TO IDENTIFY TWO LAWS OF
INHERITANCE A. MENDEL'S EXPERIMENTAL, QUANTITATIVE APPROACH
1. BACKGROUND -
2. GARDEN PEA EXPERIMENTS -
B. THE LAW OF SEGREGATION 1. DATA AND ANALYSIS -
2. MENDEL'S MODEL a. FIRST POINT -
b. SECOND POINT -
c. THIRD POINT -
d. FOURTH POINT -
3. USEFUL GENETIC VOCABULARY -
4. THE TESTCROSS -
C. THE LAW OF INDEPENDENT ASSORTMENT -
II. THE LAWS OF PROBABILITY GOVERN MENDELIAN INHERITANCE -
A. THE MULTIPLICATION AND ADDITION RULES APPLIED TO
MONOHYBRID CROSSES -
B. SOLVING COMPLEX GENETICS PROBLEMS WITH THE RULES OF
PROBABILITY -
III. INHERITANCE PATTERNS ARE OFTEN MORE COMPLEX THAN
PREDICTED BY SIMPLE MENDELIAN GENETICS -
A. EXTENDING MENDELIAN GENETICS FOR A SINGLE GENE -
1. DEGREES OF DOMINANCE -
2. THE RELATIONSHIP BETWEEN DOMINANCE AND
PHENOTYPE -
3. FREQUENCY OF DOMINANT ALLELES -
4. MULTIPLE ALLELES -
5. PLEIOTROPY -
B. EXTENDING MENDELIAN GENETICS FOR TWO OR MORE GENES 1. EPISTASIS -
2. POLYGENIC INHERITANCE -
C. NATURE AND NURTURE: THE ENVIRONMENTAL IMPACT ON
PHENOTYPE -
1. NORM OF REACTION -
2. MULTIFACTORIAL CHARACTERS -
D. INTEGRATING A MENDELIAN VIEW OF HEREDITY AND
VARIATION -
IV. MANY HUMAN TRAITS FOLLOW MENDELIAN PATTERNS OF
INHERITANCE -
A. PEDIGREE ANALYSIS -
B. RECESSIVELY INHERITED DISORDERS -
1. THE BEHAVIOR OF RECESSIVE ALLELES -
2. CYSTIC FIBROSIS -
3. SICKLE-CELL DISEASE -
C. DOMINANTLY INHERITED DISORDERS -
1. ACHONDROPLASIA -
2. HUNTINGTON'S DISEASE -
D. MULTIFACTORIAL DISORDERS -
E. GENETIC TESTING AND COUNSELING -
1. COUNSELING BASED ON MENDELIAN GENETICS AND
PROBABILITY RULES -
2. TESTS FOR IDENTIFYING CARRIERS -
3. FETAL TESTING -
4. NEWBORN SCREENING -
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