EMBO workshop - program Sunday evening, March 6, 2011 15.00 17:00 18:00-19:00 19:00-20:30 20.45-21:45 Start of registration Guided Tour through Castle Rheinfels Get together Dinner Keynote speaker Pascale Cossart Entrapment of Intracytosolic Bacteria by Septin Cage-Like Structures Monday, March 7, 2011 Session 1 – Structure of Septins 9:00 – 9.30 Jeremy W. Thorner Phosphatidylinositol-4,5-Bisphosphate Promotes Budding Yeast Septin Filament Assembly and Organization 9:30 – 10.00 Helge Ewers Superresolution Microscopy of Mammalian Septin Complexes 10.00 –10:30 Eldar Zent/Fred Wittinghofer Structural and Biochemistry Studies on Sept7 10:30-11:00 Coffee Break Session 2 – Septin Interactions 11:00-11:30 Makoto Kinoshita What is the Physiological Role of the Cdc42-Borg/Cdc42ep-Septin Pathway? 11:30-12:00 Kirstin Sandrock/Barbara Zieger Characterization Human endothelial and platelet septin SEPT11 12:00-12:30 Koh-ichi Nagata Role of Septins in Neural Cell migration during brain developmentScreening of Novel Interacting Partners 12.30-14:00 Lunch Session 3 – Septins and Yeast 14:00-14:30 Daniel J. Lew Dynamics of Septin Ring Formation in Yeast 14:30-15:00 Two short talks: Fabrice Caudron: Asymmetric Segregation of a Prion-mediated Memory in Budding Yeast Franz Meitinger: Characterization of the Cell Cycle Regulated Association between the F-BAR Protein Hof1 and Septins 15:00-15:30 Erfei Bi Revisiting the Role of Septins in Cytokinesis in Budding Yeast 15:30-16:00 Boarding the boat on the River Rhine 16:00-18:00 Septin Research Discussion during River Cruise with Coffee and Cake 18:30-20:30 Poster Session and Drinks 20:30-22:00 Dinner and Wine Tuesday, March 8, 2011 Session 4 – Septins and Cytokinesis/Cell division 9:00 – 9.30 William Trimble Septin Assembly and Function During the Cell Cycle 9:30 – 10.00 Xuebiao Yao Molecular Dissection of Acetyl-Regulation of Septin Dynamics in Mammalian Cell Division 10.00 –10:30 Two short talks: Amy Maddox: High-Resolution imaging and Computational Modeling propose Roles for Septins During Cytokinesis. Roland LeBorgne: Role of Septins in Asymmetric Cell Division and Notch Signaling in Drosophila 10:30-11:00 Coffee Break Session 5 – Septins and Mammals 11:00-11:30 Ernst-Martin Füchtbauer Conditional Deletion of Septin9 in Mice 11:30-12:00 Two short talks: Aminata Toure: The Membranous Anion Transporter Tat1 (Testis anion transporter 1) Co-Localizes and Interacts with Septin 4 at the Annulus of Mouse and Human Sperm Flagellum Werner Hauke: A Septin Filament Stabilizes Central Nervous System Myelin 12:00-12:30 12.30-14:00 Elias Spiliotis Sensory Axon Branching Requires the Sequential Action of SEPT6 and SEPT7 Lunch Session 6 – Novel Septin Assemblies 14:00-14:30 Amy Gladfelter Dynamic, Paired Septin Filaments Form in Vivo With a Molecular Organization Conserved From Fungi to Mammals 14:30-15:00 Two short talks: Mikael Sellin Assembly Order and Subgroup Configurations of Septin Oligomers in Human cells Richard Garratt Septin Structure and Assembly: a Look at the C-Terminal Domain 15:00-15:30 Yves Barral Septins and the Assembly of Diffusion Barriers in Yeast 15:30-16:00 Coffee Break Session 7 – Septins and Cancer 16:00-16:30 Hilary Russell The Pathobiology of Perturbed Septin Expression in Neoplasia 16:30-16:45 1 short talks: Cristina Montagna The Expression of Septin 9 in Human Breast Cancer 16:45-17:15 Nuno Cerveira MLL-SEPTIN rearrangements and gene fusions in haematological malignancies 17.30-19:00 Poster Session and Drinks 19:30 Meeting Dinner and Wine Tasting Wednesday, March 9, 2011 Session 8 – Septin and Diseases 9:00 – 9.30 Nicola J. Mabjeesh Bivalent Roles of SEPT9 in HIF-1 activation 9:30 – 10.00 Hermann Steller/Sarit Larisch Role of the pro-apoptotic ARTS (Sept4_i2) Protein in Apoptosis and Tumor Suppression 10.00 – 10:30 Ian G. Macara A New DNA Repair Nuclease Links Mammalian Septins to the DNA Damage Response 10:30-11:00 Coffee Break Session 9 – New and special Functions of Septins 11:00-11:30 Two short talks: Yasin Dagdas Septin-mediated Morphological Transitions during Plant Infection by the Rice Blast Fungus Björn Sandrock Filamentous Septin in the Corn Smut Fungus Ustilago maydis is Specifically Recognised by Gap7, a novel Cdc42 specific GTPaseactivating protein 11:30-12:00 12:00-13:00 13:00-15:00 Special Lecture John R. Pringle Septin Research: Genesis and future aspects Plenary Discussion and Summing up of the Meeting Lunch or Lunch Boxes and Departure