YOUR MEDICATIONS AND YOU To maximize the effect of your medication, it is really important to follow your doctors and pharmacist instructions very carefully. Certain medications are prescribed to prevent the risks of angina and/or heart attack. You have to take all medications as prescribed regularly. It may be necessary for you to take a combination of medications. There are some medications of “prolonged action”. These medications’ names are often followed by LA, SR, CD or XL. They must not be broken, cut or chewed. ASPIRIN NON COATED COATED Aspirin 325/80 mg Entrophen 325 mg Novasen 325 mg/300 mg MSD AAS 325 mg Asaphen 80 mg This drug thins the blood. It decreases the risk of blood clot formation. This medication has to be taken with food as it can irritate the stomach. Special coating of the Aspirin may help protect your stomach. If you are prescribed the coated aspirin, do not chew, cut or break the pill. NITROGLYCERIN This medication is highly effective in decreasing chest pain related to angina. It opens the coronary arteries thus bringing more oxygen to the heart. It can also be taken before effort or stress to prevent angina. Differences between the pills and the spray of Nitro Pills Spray Dose 0.3/0.6 mg 0.4 mg To be taken under the tongue on or under the tongue Can be kept 3 months from date of opening up to 3 years Caution Do not swallow or chew Keep in its original bottle Not to be inhaled, shaken To be given with the spray directed upward ALWAYS HAVE NITRO WITH YOU. TO BE KEPT FAR FROM HEATED AND HUMID PLACES It is very important to lie or sit down before you take this medication. SIDE EFFECTS: 1. Headaches, 2. Dizziness 3. Flushing, warmth 4. Rapid heart beat WHAT TO DO WHEN YOU HAVE CHEST PAIN When you have chest pain, it is not possible to know if it is angina or a heart attack, it is then important to follow these steps: 1. Stop the activity that you are doing, lie or sit down. 2. Take one (1) Nitro pill or spray. Close your mouth and do not swallow. 3. If the pain is still present after 5 minutes, take a second Nitro and then wait for 5 more minutes 4. If the pain is still there, take one more (third) Nitro. 5. If 5 minutes after the third Nitro, you still have the pain, call 911 for an ambulance to go to the hospital immediately. Types of medications NAME ACTION NITRATES Imdur Isordil Nitro-dur Nitrong-SR Transderm-Nitro Minitran Increase oxygen delivery to heart Opens coronary arteries Nitro-patch: Usually 10-12 hrs off. Imdur: usually take at wake up. Isordil: 30 mins before meal SIDE EFFECT Increases heart rate Headaches, Dizziness, flushing WHEN TO TAKE BETA-BLOCKERS Betaloc (Metoprolol) Corgard (Nadolol) Tenormin (Atenolol) Lopressor (Metoprolol) Sectral (Acebutolol) Sotacor (Sotalol) Trandate (Labetalol) Transicor (oxyprenolol) Visken (Pindolol) Coreg ( Carvedilol) Inderal (Propanolol) Decrease demand for oxygen Decreases heart’s work Decreases heart rate With Meals CALCIUM BLOCKERS AdalatPA/XL (Nifedipine) CardizemCD/SR (Dilitiazem) IsoptinSR (Verapamil) Chronovera Verapamil Norvasc (Amlodipine) Plendil (Felodipine) Renedil (Felodipine) Decreases heart work Increases oxygen delivery to Heart. Decreases oxygen demand of The heart Adalat/Isoptin, avoid grapefruit juice. Take at regular intervals Decreases heart rate Decreases heart rate, Cold hands & feet Constipation, Headache, Fatigue, Insomnia, Fatigue, swelling of the feet. Nightmares, Decreases libido, Impotence Names Action How to take Side effects Angiostenine converting enzymes Diuretics Inhibitors Accupril (Quinapril) Altace (Ramipril) Copten (Captopril) Versyl (Perindopril) Inhibase (cilazapril) Lotensin (Benazepril) Monopril (Fosinopril) Prinivil / Zestril (Lisinopril) Vasotec (Enalapril) Promotes healing of the heart after a heart attack Controls blood pressure Decreases the failing of the heart Lasix (Furosemide) Hydrodiuril (Hydrochlorothiazide) Lozide(Indapamide) Perindopril and captopril have to Be taken on an empty stomach. To be taken in AM The other medications can be taken with/without foods Increases the blood’s potassium Avoid Potassium supplements Unless prescribed by your MD. Dry cough. Takes off the surplus of water Controls blood pressure If you are prescribed > 1dose/day, last dose should not be taken later than 18h00 (6PM) More frequent voiding Dizziness Lowers blood’s potassium Sun Sensitivity, to use sunscreen MEDICATIONS TO DECREASE CHOLESTEROL TRADEMARK GENERIC NAME HOW TO TAKE Bezalip SR Bezafibrate With breakfast & supper Lipidil Micron Fenofibrate With supper Lopid Gemfibrosil 30 mins before breakfast & supper Mevacor Lovastatin With supper Lescol Fluvastatin At bedtime Pravachol Pravastatin At bedtime Zocor Simvastatin At bedtime Lipitor Atorvastatin At bedtime These medications help decrease cholesterol and/or triglyceride in the blood. Decreasing cholesterol helps lower the risk of coronary artery disease (angina, heart attack). These medications can cause headaches, dizziness, diarrhea, constipation, flatulence, nausea especially at the beginning of treatment. If these problems persist, inform your doctor. Very rarely, they may cause fatigue, muscle weakness, and muscular pain. Notify your doctor immediately if you have any of the muscular weakness/pains. It is still very important for you to follow the special diet to lower your cholesterol. Your doctor will also prescribe regular blood tests to follow your cholesterol and triglycerides. GENERAL RECOMMENDATIONS 1. Keep all your medications away from direct heat or humidity or direct exposition to the sun. Do not store them near a stove, refrigerator, in the bathroom or glove compartment. 2. Keep them locked and away from children. 3. Go to the same pharmacy. This will help them to keep a complete and updated list of your medications. He/she can contact your doctor, if needed. Always ask your pharmacist’s opinion before buying over the counter medications. They may be dangerous for you, or can interact with your other prescribed medications. You can ask your pharmacist about the program “medications codes” for over the counter medications. The products identified by letters (A,B,D,E,H,X) should be consumed with precaution. You have to check with your pharmacist about these products. 4. Always renew your medications a few days in advance so that you will not run out of medications. Always check how many renewals are left. Let your doctor know in advance when you have no renewals left. 5. You cannot stop, increase or decrease the dose of any of your medications without the approval of your doctor. If you believe you are having side effects from one of your medications, contact your doctor or pharmacist. Do not wait until your next appointment with your doctor before clarifying the situation. 6. Always keep with you an updated list of your medications 7. Notify your doctor/dentist of all your medications before any surgery or dental manipulation. 8. Some cardiac medications can cause dizziness. You can decrease these problems by getting up slowly from lying or sitting positions