MCB 408 - 2008 MCB 408 (MCB493) Tuesday/Thursday Immunology 9:30 – 10:50 A.M. Spring, 2008 314 Altgeld Instructor: David M. Kranz Professor of Biochemistry Office: 352C Burrill Hall Phone: 244-2821; E-mail: d-kranz@uiuc.edu Office Hours: Tuesday 1–2; Wed 9–10 Teaching Assistant: Carolina Soto, Graduate student in MD/PhD program (Neurobiology) Office: 336 Burrill Hall; Office Hours: To Be Determined Phone: 244-7315; E-mail: csoto@uiuc.edu Course Description: Cellular and molecular basis of immune responses to infectious agents and cancer. Structural and biochemical understanding of key immune molecules. In addition to basic immune system components (such as B and T cells), topics will include autoimmune diseases, infectious diseases, cancer, allergic responses, and immunotherapeutics. Textbook: Required: Kuby Immunology, Sixth Edition, by Kindt, Goldsby, and Osborne, 2007, W.H. Freeman and Company, New York Lecture Content: Approximately 60% will be derived from the Kuby Immunology textbook and 10% from the textbook Immunobiology: The Immune System in Health and Disease, 6th Edition, by Janeway et al, 2005, Garland Science (not a required text). The remaining 30% will be from reviews, primary literature, newspapers, web sites, movies, you name it. Web Access: A password accessible web site will contain all Power Point Lectures and some other material. Further information to be provided at first lecture. Grading: Four exams, each worth 25% of grade. Final exam will not be comprehensive but will cover the last quarter of the course. Last years exams, with and without answers, will be posted for your use. Keep in mind that these past exams also covered some material (about 20%) from Discussion sections, which are not offered this year. Approximate course grade distribution will be 40% A, 40% B, 20% C. Student’s who clearly do not try, as evidenced by exam scores that are well below average, and outside a Gaussian distribution, may receive a D or even an F. 1