A Classroom Epidemic Student Learning Objectives: 1. Determine mode of transmission for an infectious agent 2. Understand the exponential increase of infection in an epidemic situation 3. Critically analyze data to determine patient zero (initiator of epidemic) Background: Microorganisms which can cause human disease are called pathogens. In order to cause disease, pathogens must be able to penetrate the first and second lines of defense of the human immune system. Once this is achieved, the infection and subsequent disease process can begin. Early in the infectious state, many disease causing agents are communicable. Communicable infectious agents can be transmitted from one person to another via direct or indirect contact. Examples of direct contact modes of transmission are kissing, touching, and sexual contact. Examples of indirect contact include contact with fomites. A fomite is an inanimate object used in the transmission of an infectious agent; for example, a doorknob or a telephone. Communicable infectious agents can also be transmitted via water, air, or food. Epidemiology is the study of the factors affecting the occurrence and transmission of a disease within a community. An epidemic is a sudden increase in the number of cases of a disease in a particular community in a given period of time. Epidemiologists are scientists who study the when, where, why and how of epidemics. In this exercise, students will act as epidemiologists. Students will simulate an epidemic using a non-toxic, non-infectious, nonbiological powder as our “infectious agent.” The student will then identify infected members of the population, mode of transmission of the infectious agent, and the originator of the epidemic. Materials: Brown paper lunch bags, one per student (1 bag filled with cornstarch, the rest filled with talc powder) Filter paper, one piece per student Iodine developer solution Procedure: 1. Pick a bag from the side table. Make a note of the number on the bag. This number is how you will be identified for this exercise. 2. Your instructor will come around and spray your right hand with water. Shake off the excess water. 3. Reach into the bag with your moistened hand and coat it with the powder in the bag. This is to simulate sneezing on your hand. 4. When your instructor tells you it is time, shake hands with one person using the hand coated with the powder. Record the number of the person you shook hands with in the first column of the data sheet (round 1). 5. When your instructor tells you it is time, shake hands with a new person and record the number of the person in the second column of the data sheet (round 2). 6. When your instructor tells you it is time, shake hands with a third person and record the number of the person in the third column of the data sheet (round 3). 7. After the third round of hand shaking, press your hand firmly to a piece of filter paper. 8. To determine who is “infected”, spray the filter paper with the iodine developer solution and look for a color change. A blue color means that you are “infected”. A brown or yellow color means that you are not infected. 9. The instructor will record all data on the overhead projector. Once all data are collected, you will be able to determine the originator of the epidemic or “patient zero”. The Epidemic – Data Sheet Person 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Round 1 Round 2 Round 3 Infected? Who started the epidemic? _________________________ Questions for Review: 1. What was the mode of transmission for this “infectious agent”? 2. Did the numbers of the infected persons increase or decrease after three rounds of handshaking? How many people were infected after rounds 1, 2, and 3? 3. What additional step must occur in order for our infectious agent to cause disease in our simulated “epidemic”? 4. Provide a scenario where a fomite could be involved in the transmission of our “infectious agent”. 5. What is the easiest and most efficient way to prevent this type of “outbreak”?