Writing Reaction Mechanism 1. Predict the major product from the reaction of the following alkene with HCl. Propose a reaction mechanism for its formation. CH3CH2CH=C(CH3)2 2. O CH3 D H3C HBr D D CH3CO2H, D Br 40oC H3C D D + H OCCH3 D D D Major H Minor a) Propose the reaction mechanism for the formation of the major product. b) Propose the reaction mechanism for the formation of the minor product. 3. Reaction of 1-phenylpropene and dilute sulphuric acid yields only 1-phenylpropanol. Propose a mechanism for the reaction and explain why this is the only isomer produced. OH H2O H2SO4 4. Triphenylmethane can be prepared by reaction of benzene and trichloromethane in the presence of AlCl3. Propose a mechanism for the reaction. + 5. AlCl3 CHCl3 H Propose a mechanism to account for the reaction of benzene with 2,5-dichloro-2,5-dimethylhexane. 1 Cl + AlCl3 Cl 6. Write a possible reaction mechanism for the following reaction. O O Cl + N NH O O 7. Methamphetamine can be synthesized by first reacting phenyl-2-propanone with methylamine. Propose a reaction mechanism of initial reaction for the formation of the intermediate as shown below. CH3NH2 HO O NHCH3 NHCH3 Methamphetamine 8. Write a reaction mechanism for the following reaction. CH3 Br2 Br hv Br CH3 9. Suggest a mechanism for the following transformation. H+ HO O OH CHO 10. In solid phase synthesis of peptides, the amino group in the amino acid is normally protected by the following reaction. Propose a mechanism for the transformation. NH2 O O O O O HN O CO2Et O CO2Et 2