Notes – Chapter 5 Tissues Tissue: collection of specialized cells and cell products that perform a relatively limited number of functions Histology: the study of tissues Major Types 1. epithelial 2. connective 3. muscle 4. neural Epithelial tissue: composed of epithelia, layers of cells that cover internal and external organs, and glands, secretory structures derived from epithelia Functions of Epithelia 1. physical protection 2. control permeability 3. provide sensation – richly innervated 4. produce specialized secretions (gland cells) Basement membrane: epithelial cells hold on to each other and remain firmly attached to the rest of the body Epithelia Simple – one cell layer covers the basement membrane, thin and delicate, found where secretion or absorption takes place ex. Gas exchange and intestines Stratified – several cell layers cover the basement membrane, found in places of great mechanical stress Shapes – squamous, cuboidal, columnar Types Simple squamous Description Cells flat (fried egg) Simple cuboidal Cubed shape Simple columnar Cells taller than wide Pseudostratified Some cells fail to reach the free surface giving the appearance of Function Diffusion, secretion, absorption Secretion, absorption, ciliary movement of mucus Secretion, absorption, ciliary movement Secretion, ciliary movement Location Alveoli, capillaries Bronchioles, kidney tubules, liver, thyroid Stomach, intestines, uterus Nasal cavity, trachea, bronchi Stratified squamous layers, all cells touch the basement membrane Several layers of flattened cells Abrasion resistance Stratified cuboidal Several layers of cubed shaped cells Sex production, lining of ducts Stratified columnar Several layers of columnar shaped cells 2-6 layers thick with the base cells cuboidal and the surface cells more flattened Transition between strat. squamous and simple columnar Allows for distention as an organ fills with fluid T ransitional Epidermis, oral cavity, esophagus, anal cavity and vagina Ducts of sweat glands and testes, follicles of ovaries Scarce, some regions of larynx and rectum Parts of urinary system only Connective Tissue Most variable, abundant and widely distributed Functions 1. binds structures together 2. provides support 3. serves as a framework 4. fills spaces 5. stores fat 6. produces blood cells 7. provides protection against infection 8. helps to repair tissue damage Cell types Resident cells: usually present in relatively stable numbers Fibroblasts: most common, large star shaped; produce fibers by secreting proteins in a matrix of connective tissue 1. collagenous fibers: thick, threadlike composed of collagen; grouped in long parallel bundles; flexible but only slightly elastic; great tensile strength ex. tendons (connect muscle to bone); abundant collagenous fibers also referred to as dense connective tissue and are sometimes called white fibers because of their light coloration 2. elastic fibers: composed of microfibrils embedded in elastin (protein); fibers tend to be branched in a mesh shape; less strength than collagenous fibers, but are very elastic (easily stretched, but can resume original shape); sometimes called yellow fibers 3. reticular fibers: very thin and composed of collagen; highly branched and form delicate supporting networks for a variety of tissues Mast cells: large cells located near blood vessels release heparin (prevents blood clotting) and histamine (vasodilator) Wandering cells: appears temporarily in tissues, usually in response to injury or infection WBC – macrophage (Listing of connective tissue see chart)