Job Title- Director of Nucleus Functions
Department- Control Center
Division-Direct Control
Scope-Direct and control all of cells activities
Major Responsibilities -Direct and control the ability of the cell to grow develop and replicate.
Oversee the functions of the nuclear envelope and lamina, the chromatin, nucleolus, mRNA and
rRNA.
Structure
The nuclear envelope is made up of two layers, the inner and outer membranes, which are
separated by a very thin space of 20-40nm, called the perinuclear space, and has perforations,
which are pores, that allow proteins to pass through. This envelope connects with the rough
endoplasmic reticulum. This envelope disintegrates during cell division but reforms afterwards.
The nuclear lamina helps support the shape of the nucleus with net-like protein filaments
within the nuclear envelope. The nuclear lamina binds to chromatin. The chromatin is a mass of
DNA and proteins. DNA is a long two-stranded molecule, shaped like a ladder and twisted into a
spiral which stores the genetic material. Genes are small segments of DNA that carry
instructions for making proteins. The nucleolus is located towards the center in the nondividing part of the nucleus. Its function is to synthesize ribosomal subunits, like ribosomal RNA
(rRNA) from instructions from the DNA. The rRNA then leaves through the nuclear pores to the
cytoplasm, and assembles into a ribosome. Messenger RNA (mRNA) is another subunit
synthesized in the nucleus and transported to the cytoplasm through the pores. The ribosome’s
function is to produce the cells proteins.
The structure of the nucleus, which includes: the nuclear envelope, lamina, chromatin, rRNA,
and mRNA, and the nucleolus is necessary for the nucleus to carry out its primary role to
facilitate making proteins.
Relationships
Internal: The nuclear envelope has close relationships with the endoplasmic reticulum
both the rough and smooth, because it is a continuous system of interconnect tubules. Further
internal relationships are with the Golgi apparatus because of the modification of its proteins.
The lysosome is also another important relationship because it breaks down ingested
substances. The vacuoles are a close contact because of its multiple functions of: digestion,
storage, waste disposal, water balance, cell growth and protection. Whenever there are
problems with cellular respiration the mitochondria can be quickly contacted and whenever
you are looking for photosynthesis help, the chloroplasts are always nearby and readily
available.
External: As Director of Nucleus Functions, you will be in constant contact with external
cells, contributing to the overall growth of specific tissues and organs. Your interactions will
vary depending on the specific tissues, for example, uterine cells, or more sophisticated organs
such as the heart and brain. More details of these interactions will be explained if you are the
successful candidate.
Are you looking to work in a fast-paced
environment with continuous ongoing activity and frequent turnover of
staff? We have recently had multiple departures. We have an opening
for a Director of Nucleus Functions to manage multiple subordinates.
Qualifications include ability to handle frequent messengers, ability to
count to 46, and measure nanometers. You need to be quick on your
mitochondria! If you are interested contact us at 1-800-46-CHROM,
extension 20-40nm.