1 Neuroanatomy Dr. Steinmetz Outline 2 • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System 1 Outline 3 • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System 4 2 Parts of the Nervous System • CNS (Central Nervous System) = Brain & Spinal Cord • PNS (Peripheral Nervous System) = all neurons found outside of the skull and spine 2 Outline 5 • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System Brain Stem & Cerebellum 6 3 7 Cranial Nerves • Summary of the functions of each cranial nerve • Red lines are afferent signals • Blue lines are efferent signals 8 Plate 5.7 on page 85 of your human neuroanatomy book This is the figure that I will use to test your knowledge of cranial nerves on the neuroanatomy lab practicals. 4 9 Outline • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System Midbrain 10 • Superior Colliculus - vision tracking • Inferior Colliculus sound localization • Tegmentum nuclei for eye movement & control • Substania Nigra – dopamine input to basal ganglion in forebrain 5 Outline 11 • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System Brain Divisions: Forebrain 12 • Limbic System • Sensory / Motor Regulation • Learning & Memory • Internal Body States 6 Amygdala 13 • Emotion Regulation • Assesses Stimulus value Thalamus 14 • Sensory / Motor Regulation 7 Hippocampus 15 • Learning & Memory Hypothalamus 16 • motivational states • Hunger • Satiety • Reproduction • Sleep 8 Outline 17 • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System Corpus Callosum 18 • Connects 2 hemispheres 9 Cerebral Lobes 19 • Occipital Lobe center for vision processing of visual sensory information Cerebral Lobes 20 • Temporal Lobe center for hearing, memory, associations, internal areas = gustatory processing 10 Cerebral Lobes 21 • Parietal Lobe center for somatosensory information / complex visual processes, associations • Separated from the frontal lobe by the Central Sulcus Cerebral Lobes 22 • Frontal Lobe complex thought, reasoning, personality, motor system, & olfactory and flavor processing 11 23 Outline • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System Spinal Cord Anatomy Dorsal Root Ganglion Motor Output 24 • Sensory nerves enter the dorsal horn of spinal cord • Motor Motor Output nerves exit the ventral horn of spinal cord 12 25 Outline • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Autonomic Nervous System – Somatic Nervous System Blood Supply to the Brain 26 • Stroke = lack of blood or O2 to the brain • Aneurysm = blockage / rupture of blood vessel • Blood is toxic to CNS neurons • Blood-Brain barrier 13 The fluid in your CNS = CSF 27 • Cerebrospinal Fluid (CSF) = ultrafiltered blood • Acts as a supporting cushion – Both externally between the brain and the skull / spinal cord – And internally to prevent collapse • Exact function unknown: (supply / waste) – Turns over 3 times a day – 0.5 liter per day Ventricles 28 28 Side view Bottom view Front view 14 Hydrocephalus “water on the brain” Outline 29 30 • CNS versus PNS • CNS: Regions • Hindbrain, Midbrain, Forebrain • Lobes • Spinal Cord • PNS: – Blood Supply, Ventricles, and CSF – Somatic Nervous System – Autonomic Nervous System 15 Peripheral Nervous System 31 • Somatic – voluntary control of body movements • Autonomic – automatic control – Sympathetic (arousing) – Parasympathetic (calming) Autonomic Nervous System 32 • 2 components control involuntary functions: Sympathetic • Stimulation • Fight or Flight (survival) Parasympathetic • Relaxation • Restore homeostasis (conserve resources) 16 Autonomic Nervous System 33 • 2 components control involuntary functions: Sympathetic • Stimulation • Fight or Flight (survival) • Activated fast by connected neural pathways • Norepinephrine (NE) Parasympathetic • Relaxation • Restore homeostasis (conserve resources) • Activated slower by individual neural pathways • Acetylcholine (ACh) For next time: 34 • Read Chapter 3 • Work on Week 1 & 2 Neuroanatomy Lab 17