Solutions for your
successful Life Science
Environments –
Powered by DESIGO™
Building Technologies
s
DESIGO™ – for optimum
environmental Conditions in
the Life Sciences Industry
The life sciences industry fully relies on comprehensive control
of environmental conditions. This is where a building automation
and control system that reliably meets technical and regulatory
requirements comes in. Deciding in favor of DESIGO™ means to
invest in the future of your company.
DESIGO™ optimally controls and monitors sensitive process environments. To
achieve this goal, special requirements
from different applications are considered to the maximum, e.g. through
energy-optimized fume-hood control
in research, exact differential pressure
control for cleanrooms as well as reliable
monitoring of warehouses by applying
Mean Kinetic Temperature (MKT) calculations. Combining a scalable system
and our application know-how from
hundreds of life sciences projects makes
DESIGO what it is: a first-rate choice for
the life sciences industry.
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Developed for the life sciences
industry
During development of DESIGO, we
apply measures that are as stringent
as those applied to the life sciences
industry. Our strict development process
influenced by GAMP is successfully audited internally and externally on a regular
basis by the pharmaceutical industry. As
a rule, life science-specific functionality
is developed in close cooperation with
the pharmaceutical indus try. This allows
us to guarantee that DESIGO will easily
master any challenge within your environment.
User-friendly solution
DESIGO offers user-friendly operation
at all system levels. Local operator units
feature transparent, intuitive operation
and clear, graphic displays. Management
station operation is based on Microsoft
Windows and is thus designed as ergonomically as possible. Each user can retrieve
the required information e.g. in the
lab, production, or logistics with just a
few mouse clicks. As a result, operating
personnel requires only little training,
and building infrastructure is securely
protected.
An investment that is well worth
the money
Introducing DESIGO does not result in
an abrupt change of the system world,
as step-by-step migration from existing
systems to DESIGO can easily be accomplished. Your investment is protected
based on the compatibility of DESIGO
with existing systems. Any possible
impact of changes on the validated
system status as well as all required
testing and qualification measures are
documented extensively. That‘s what
we call investment protection. DESIGO
grows with you and your requirements:
from a small biotech research lab to a
globally active pharmaceutical company
– our system always fits your processes.
Our broad, modular automation station
product range, various operator units,
and a flat system topology allow for
cost-effective introduction of DESIGO
even in small projects. At the same time,
small projects can be extended any time
to complex, large projects.
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DESIGO™ – gain Advantages
through Consistency
The future belongs to building automation and control that convinces by
consistency. A system that allows for standardizing automated processes.
A guarantee for comprehensive monitoring and harmonized operation
of the entire building.
The DESIGO™ pharmaceutical applications were developed in close cooperation with the pharmaceutical industry.
Regular vendor audits provide documented proof that DESIGO is particularly
suited to validated environments. Other
advantages are:
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Individual management station
operation:
• Harmonized view and pictures
• Simple, multi-disciplinary operation
• Common log and alarm management
■ Peer-to-peer communications:
• Information available where it is
needed
• Automatic interaction and data
exchange
■ Flexibility:
• Changes without rewiring and new
hardware
■ Operational efficiency improves
profitability:
• Low operating costs
• Low training costs
■
Support 21 CFR Part 11 compliance
DESIGO supports the safety of electronic
data and electronic signatures as per 21
CFR Part 11 and EU Annex 11 through
comprehensive measures such as access
control, audit-trail, backup and archiving
functions.
DESIGO provides intuitive access to all
required information of the building
infrastructure. Integration options cover
the following functionality and are
extended on an ongoing basis.
Optimum climate
DESIGO allows you to control room conditions to exactly what‘s required for the
processes. Accurate temperature and
humidity control provide optimum environmental conditions e.g. in production.
Monitoring and reporting
All quality-relevant parameters are recorded reliably and archived for decades
in protected databases. Intuitive and
automatically generated reports provide
exactly that information that you require
e.g. to provide proof for the long-term
stability of your products.
Optimized power supply
We can increase your system availability,
reduce down-time and provide for transparent energy consumption data by
integrating your plants used to supply,
convert and distribute high and low
voltages. Integrated coordination signals
optimize operation of various HVAC
plants, e.g. by means of demand-controlled cooling and heating generation
in dependence of room demand. Thus,
electrical consumption, among others,
can be directly controlled and optimized.
Fast intervention in the event of a fire
Reliable fire detection is a special
challenge in the life sciences industry
due to the high air change volumes. The
systems by Siemens detect – deceptionproof – a fire in its earliest state and are
able to differentiate between various
types of flame and smoke. Integration in
DESIGO significantly increases safety of
personnel and assets, as e.g. ventilation
control allows to optimally coordinate
reactions to a fire.
Integrated safety
In critical environments, handling toxic
substances, for example, represents
a constant threat to the health of personnel. DESIGO controls the pressure
difference as well as the air change rate
for the safety of personnel. And, the
lab management application monitors
itself and triggers an alarm upon each
malfunction or bad operator action.
Integration of the entire physical safety
e.g. through access control and video
surveillance systems further enhances
safety for both personnel and processes.
Comfortable conditions that allow you
to focus on your core processes
Complex research and development
processes in the life sciences industry
require that experts work at their very
best within comfortable environmental
settings. DESIGO supports this type of
challenge by integrating operation of
all room functions such as lighting and
blinds control with automatic access
control systems that are also used to
secure IT-systems and pay for food
purchases at the canteen.
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DESIGO™ –
easily communicate with
worldwide Standards
Intelligent communications are a decisive factor in evaluating
the benefits of a building automation and control system:
Smooth data exchange with the existing infrastructure and
common applications are a prerequisite. BACnet is a globally
recognized standard.
Management Level
DESIGO INSIGHT
Client
InfoCenter
Server
DESIGO INSIGHT
Server
Printer
DESIGO Tool Set
Printer
ETHERNET TCP/IP
BACnet
IP Router
Automation Level
Integral
DESIGO PX
LON
VISONIK
PX compact
PXM20-E
PX modular
Typical topology for a building
automation and control network
for the life sciences industry.
Avoiding costly gateway solutions to
exchange data is increasingly important
when installing a building automation
and control system. BACnet, the communications protocol, can easily combine
conformant devices. Thus, all network
members in a building can access the
functions and data of the connected
devices.
Consistent communications
DESIGO™ uses the open communications
protocol BACnet (Building Automation
and Control Network) to exchange data
between the DESIGO PX automation
stations and the automation and
management levels. BACnet, a global,
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future-oriented standard, was developed
under the auspices of ASHRAE (American
Society of Heating, Refrigerating and Air
Conditioning Engineers) with building
technology in mind.
The flexible communications solutions
allow for reliable separation of GxP- and
non-GxP-relevant systems, thereby
increasing security of sensitive data and
significantly lower validation efforts. Our
planning guidelines for the life sciences
industry ensure that your sensitive data
are protected as per EU GMP and cGMP
requirements in cross-discipline communications.
DESIGO – sensitive
environmental Conditions
under Control
Plant Viewer
Practical pictures allow for fast,
target-oriented system monitoring
and operation.
Transparent and consistent operation opens up new
dimensions to reliably monitor processes in research and
development, production or warehouses.
The DESIGO INSIGHT management station
helps visualize and operate different
processes in a building. It contains a
comprehensive set of applications tailored
to building automation and control
that is easy to handle and economic at
the same time. The capacity of DESIGO
INSIGHT is impressive: Many buildings
can be centrally operated from one single
management station, which greatly
reduces operating costs.
Flexible alarm management
DESIGO INSIGHT allows you to centrally
acquire, edit and evaluate alarms from
all integrated systems. The high-performance alarm routing function allows you
to route alarms to SMS, fax, E-mail, pager
regardless of where operators are and if
the management station is manned.
Developed for 21 CFR Part 11
conformance
DESIGO INSIGHT secures sensitive data
at system and database level and applies
further technical measures to support
conformance to 21 CFR Part 11. Access
to data is protected reliably and each
change can be traced in the integrated
audit-trail. Pharma-specific backup and
archiving functions secure the system
and data over the entire life cycle.
Targeted optimization
Fully integrated, historic and real-time
data processing allows for fast and targeted plant optimization. Comprehensive
reporting functions and GxP-conformant
long-term archiving are provided as part
of InfoCenter.
Economic application
We integrate the energy consumption
meters of the various plants in the
building. The building automation and
control system continuously registers the
corresponding data. This allows for comparing consumption values to budgets.
Regular reports (e.g. energy signature)
track the efficiency of optimization
measures and provide the basis for
further, meaningful measures.
Scalable and extendable systems
DESIGO INSIGHT can be used for any
building size. The offering ranges from
small systems with just a few data points
to solutions for large building campuses
with several thousand data points.
DESIGO INSIGHT offers an ideal solution
for independent research laboratories
to pilot production plants to large-scale
production of generic drugs.
Time Scheduler
Central programming of all timecontrolled, building services functions including individual room
control. Simple graphical operation
of weekday, holiday, and exception
day programs.
Alarm Viewer
Detailed alarm overview for several
buildings. Users can directly access
the corresponding plant picture for
fast troubleshooting.
Alarm Router
Flexible, time-dependent alarm
routing via SMS, fax, E-mail and
pager ensures optimum deployment
of service technicians.
Log Viewer / Audit-Trail
All events (alarms, system messages
and user activities, etc.) are recorded in chronological order and can
be displayed any time for further
analysis.
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DESIGO™ – simple Display
of complex Matters
Processes depicted on a building automation and control
system‘s user interface are very complex. For this reason,
user-friendly graphical displays are a must. The same is true
for easy, logical operation. DESIGO™ INSIGHT converts complex matters into easy-to-understand graphics.
The graphics‘ options offered by the
DESIGO™ user interface satisfy every wish.
Complex, climatic relationships such as h/xdiagrams, load shedding or heating curves
are displayed in an easy-to-understand
manner. Integration of AutoCAD™ plans
and other formats compatible with Windows allows for displaying e.g. sensitive
measured values in your rooms by using
the floor plan.
Simple integration
Consequent and targeted deployment
of standard technologies as well as the
integrated SCADA software (Supervisory
Control and Data Acquisition) guarantee
that third-party systems can easily and
without problems be connected to DESIGO
INSIGHT via BACnet, OPC (OLE for Process
Control) or other interfaces. This allows
for harmonized operation of all technical
installations in a building.
Trend Viewer
Historic and real-time data processing allows for fast and targetoriented operating optimization.
Object Viewer
Allows for fast access to all objects
and parameters in the system and
the technical plants.
DESIGO™ Terminal Server
Access to the entire management
system on the network.
Further applications
Applications to configure the system,
energy and maintenance management,
system diagnostics, etc. complement
the multifaceted selection of functions.
Distributed and efficient operation
using the DESIGO terminal server
The DESIGO terminal server offers all
system functions as terminal services in
the network, allowing operators to concurrently access the data in independent
sessions. Configuration management and
project validation efforts are reduced drastically, as the DESIGO INSIGHT client does
not need to be installed on each operator
system.
Standardized technology
The DESIGO INSIGHT management station
applies a broad range of standard technologies such as ActiveX, DCOM, OLE and
Microsoft SQL server. For this reason, it
can easily be installed in standard
IT-systems and seamlessly integrated in
the existing IT-infrastructure.
Third-party software
Third-party programs can be
integrated via standard interfaces.
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InfoCenter – GxP-compatible
Monitoring and Reporting
Security
The access to electronic records
and reports is highly protected.
Archiving
Reliable archiving of your sensible
data through the entire life cycle.
21 CFR Part 11 ready
Support 21 CFR Part 11 compliance
with technical measures and
comprehensive validation support.
InfoCenter Spreadsheet
Dynamic but secure data processing of InfoCenter databases e.g.
with Microsoft Excel.
Integration of 3rd party systems
Efficient data acquisition from 3rd
party systems as OPC client or via
API interface.
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In addition to exact room conditions control, the life sciences industry not only requires efficient, documented
proof of it but also must be able to store this information
for decades. InfoCenter was developed with exactly
these tasks in mind.
Each day, the DESIGO™ building automation and control system provides
important information on current room
conditions, user intervention, alarms, warnings, and system functions. The respective
processes and installations determine the
type of information that must be used for
quality-relevant decisions. InfoCenter
enables us to prepare this information
allowing you to gain a quick overview
commensurate with the target audience‘s
needs and make well-grounded decisions.
As head of production, you for example
receive a complete report printout, a pdf
file on your network or a report that you
can open via the web.
Data security
InfoCenter was designed for large data
volumes and is based on the strength and
flexibility offered by Microsoft SQL server.
Data access is controlled by comprehensive security measures and any change is
recorded meticulously in the integrated
audit trail.
Reliable data archiving
InfoCenter automatically archives your
sensitive data and reports securely and
reliably. Reading back archives e.g. in the
case of an inspection occurs automatically,
and the system even recognizes time
periods distributed across several archiving media.
Technical solutions for 21 CFR Part 11
InfoCenter was developed for and in
cooperation with the life sciences industry.
For this reason, it supports without compromise the required security functions
under 21 CFR Part 11 such as data security,
access control, audit trail, backup and
archiving. We support your conformance
by our comprehensive validation services
along with extensive training of your users
through our modular training program
developed for the life sciences industry.
InfoCenter – turns raw
Data into Information
InfoCenter turns raw report data into transparent sets of
information. Trend curves for room conditions as well as
tables for queued alarms on limit value violations along
with user activity information on the same page are just
one example.
The integrated Report Manager allows you
to create an individual report template
with just a few mouse clicks. You can display statistical evaluations, system messages, limit value violations, etc. in addition
to the underlying building automation and
control system data. An “out-of-specification report“ that only shows deviations of
required limit values is just one mouse
click away.
Comprehensive mathematical functions
allow for highly complex calculations from
average value to Mean Kinetic Temperature (MKT).
The reports created in InfoCenter can be
signed using electronic authentication and
are thus considered a full replacement of
traditional, printed copies.
Protected web access to the InfoCenter
server provides exactly the information
each user needs. Remote operation allows
e.g. starting reports and analyzing audittrails.
Calibrated sensors record sensitive
data on site.
For technical personnel.
Comfortable reading of all necessary
system information.
On-site operation via local touch
panel offering the entire functionality of DESIGO™ INSIGHT.
For technical personnel.
Customized manual and emergency
operator levels provided in the
control panel.
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DESIGO™ – profit
from our comprehensive Solution
All-rounder in its truest meaning: DESIGO™ PX controls
and monitors, i.e. it manages heating, ventilation, air
conditioning and other building services plants.
DESIGO PX convinces not just by the scalability of its
programmable automation stations with various operator units, but also by its openness.
A family of programmable
automation stations
DESIGO™ PX offers maximum flexibility
through its family of freely programmable automation stations. Allowing
for optimum control and monitoring of
building services plants. Comprehensive
system functions such as alarming,
scheduler programs and trend cover all
technical requirements in a building. The
automation stations work autonomously
and decentralized, and are available in
two series. The open BACnet protocol on
LON or Ethernet/IP is used for communications.
DESIGO PX compact series
Compact series
■ Peripherals can be connected directly
■
Compact, space-saving constructions
featuring digital and universal I/Os for
the most varied applications. The process
periphery is connected directly to the
automation stations.
A family of programmable automation stations
DESIGO I/O module product range
DESIGO PX modular series
■ Modular
■ Flexible data point mix
■ Manual operation via modules
featuring switches and display
■ Optimum adaptation to technical
plants
The DESIGO I/O module product range
can be connected to the modular series.
The various I/O modules allow for
optimum manual/emergency operation
of various plants and thus offer service
operation for technical personnel in the
event of emergencies.
Engineering, commissioning
and service
We provide professional software tools
and a number of tested application
blocks to engineer and edit automation
stations.
User-friendly function and application
blocks in D-MAP (DESIGO Modular
Application Programming) are the basis
for engineering program functions. The
application library was specified and
tested in detail and is configured for your
project and your application. The blocks
correspond to GAMP software category 4;
as a result, only the application needs to
be validated for your project, significantly
speeding up validation as a whole. The
graphical user interface of the software
tools guarantees efficient handling. Trend,
reporting and analysis functions support
commissioning.
Professional software tools
Long-term experience
DESIGO is based on many years of experience in building automation and control
and the pharmaceutical industry. D-MAP
and all system functions are proven functions employed successfully in hundreds of
projects.
Ventilation plant
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Volume flow controller for
laboratory fume-hoods
DESIGO™ – for top-notch
Security, Energy Efficiency
and Comfort in Laboratories
Secure and efficient control of laboratories places high
requirements on building automation and control.
Thanks to its comprehensive LabManagement solution, DESIGO™ offers the highest possible energy efficiency, security and comfort for laboratory ventilation.
Sensor to acquire the front slider
position of the lab fume-hood
Lab rooms comprising fume-hoods
represent the heart of a lab. We offer a
comprehensive solution for each lab and
each fume-hood based on DESIGO™.
Top-notch quality, flexibility and cost
efficiency is guaranteed by means of the
global LONWorks communications standard and components from the DESIGO
system.
Operating unit for laboratory
fume-hoods
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Security
The system offers maximum control
stability and accuracy combined with fast
damper actuators and accurate volume
flow control. Sophisticated monitoring of
the entire system along with the volume
flows allows for immediately detecting
any system errors or problems with lab
operations, alerting the operator to the
events. The messages are displayed
clearly on the DESIGO INSIGHT manage ment station.
Efficiency
Saving energy and costs begins in the
planning phase and ends in ongoing
optimization of the laboratory. Each cubic
meter of air that does not need to be
treated positively influences your energy
balance. Nevertheless, this cannot be at
the expense of security, and regulatory
requirements e.g. on air change rates
must be upheld at all times. DESIGO is
able to support all of these tasks, and we
will support you to exploit your building‘s
energy savings potential through competent consultancy for building planning
and operational optimization.
DESIGO – LabManagement
Comfort
Simple and functional operation is
prerequisite to secure and comfortable
operations. Reliable reduction of drafts,
avoiding ventilation noise emissions, and
stable temperature control significantly
impact performance of personnel working in such environments. DESIGO
offers intuitive operation of all room
functions together with lighting and
blinds control, allowing you to focus on
your core competencies.
Integrated precision and system
stability
■ The front slider position in the fumehood is recorded to determine the
fume-hood volume flow setpoint.
Compensating for external influences
significantly improves system stability.
■ Acting pressure procedures are applied
to volume flow measurement for fumehoods and labs. High-precision pressure sensors calibrated and monitored
automatically are used as sensing
elements.
■ Highly dynamic actuators with integrated damper angle measuring equipment are used to position the damper.
■ The setpoint for room supply air volume
flow is formed via the volume flow
balance of the entire extract air to
increase system stability within the
laboratory.
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Siemens Ltd
Building Technologies
Units 1006-10
10/F, China Resources Building
26 Harbour Road
HK - Wanchai
Tel. +852 2870 7888
Fax +852 2870 7880
Siemens Building Technologies Ltd
Hawthorne Road
Staines
Middlesex TW18 3AY
England
Tel. +44 1784-46 16 16
Fax +44 1784-46 46 46
www.sbt.siemens.com/uk
Siemens Pte Ltd
Building Technologies
The Siemens Center
60 MacPherson Road
SG-Singapore 348615
Tel. +65 6490 6000
Fax +65 6490 6001
The information in this document contains general descriptions of technical
options available, which do not always have to be present in individual cases. The
required features should therefore be specified in each individual case at the time
of closing the contract.
Subject to change • Order no. 0-91999-en •
© Siemens Switzerland Ltd • Printed in Switzerland • 20607 Ni/Ah
www.siemens.com/buildingtechnologies-pharma
Pictures with kind support of Spirig Pharma Ltd., Egerkingen, Switzerland
Siemens Switzerland Ltd
Building Technologies Group
International Headquarters
Gubelstrasse 22
CH-6301 Zug
Tel. +41 41-724 24 24
Fax +41 41-724 35 22
www.siemens.com/buildingtechnologies