1 Electrophysiology Curriculum Section of Cardiology Dartmouth-Hitchcock Medical Center 2007-2008 I. Overview of Rotation Clinical cardiac electrophysiology is a rapidly expanding field that requires additional training beyond that of the general cardiologist to be competent in all its aspects. However, it is necessary for the general cardiologist to be aware of the various electrophysiologic disease states, so that he/she can make appropriate management decisions about his/her patients. The following curriculum will allow the cardiology trainee to achieve this goal. It is based on the 2006 ACC document on Core Cardiology Training in Adult Cardiovascular Medicine (COCATS 2006 Focused Updates), http://www.acc.org/qualityandscience/clinical/competence/nuclear/TF6.pdf II. Core Competencies At least 2 months of clinical cardiac electrophysiology rotation is required for all general cardiology trainees to acquire knowledge and experience in the diagnosis and management of bradyarrhythmias and tachyarrhythmias. Every cardiology trainee will learn the indications for and limitations of electrophysiologic studies, the appropriate use of pharmacologic and nonpharmacologic therapeutic options, and the proper and appropriate use of antiarrhythmic agents, including drug interactions and proarrhythmic potential. The trainee will be exposed to noninvasive and invasive techniques related to the diagnosis and management of patients with cardiac arrhythmias that include ambulatory electrocardiographic (ECG) monitoring, event recorders, exercise testing for arrhythmia assessment, tilt-table testing, invasive electrophysiologic studies, and implantation of cardiac arrhythmia control devices. Electrocardiographic manifestations of arrhythmias will be taught on a regular basis during formal ECG and EP conferences. They will be supplemented by rotation on the arrhythmia consultation service, during which time the trainee will gain first-hand experience as a consultant in arrhythmia management. Arrhythmias associated with congenital heart disease, cardiac and noncardiac surgical patients are important components of the arrhythmia core training. The trainee’s experience will also include learning the fundamentals of cardiac pacing, recognizing normal and abnormal pacemaker function, knowing indications for temporary and permanent pacing and the implantation of ICDs, knowing pacing modes, and understanding basic techniques for interrogation, programming, and surveillance of pacemakers and ICDs. The trainee will also learn about the indications for the use of biventricular pacing in patients with congestive heart failure. The cardiology trainee will be formally instructed in and gain experience with the insertion, management, and follow-up of temporary pacemakers; measurement of pacing and sensing thresholds and recording of electrograms for management of patients with temporary pacemakers; and indication and techniques for elective and emergency cardioversions. Insertion of a minimum of 10 temporary pacemakers and performance of at least 10 elective cardioversions are required. These experiences can be obtained throughout the clinical training period. 2 As volumes permit, trainees may obtain proficiency in the surgical aspects of transvenous bradycardia device implantation (pacemakers). The pacemaker implantation training will include development of expertise in permanent atrial and ventricular lead placement, threshold testing and programming of devices, principles of surgical asepsis, surgical techniques of implantation, and management of implant related complications. Individuals receiving qualifying training in pacemaker implantation must participate as the primary operator (under direct supervision) in at least 50 primary implantations of transvenous pacemakers and 20 pacemaker system revisions or replacements. The trainee must also participate in the follow-up of at least 100 pacemaker patient visits and acquire proficiency in advanced pacemaker electrocardiography, interrogation, and programming of complex pacemakers. Credentialing for permanent pacer implantation will require a total of 1 year of advanced training beyond the cardiology core level. This will include 6 months of training in non-invasive arrhythmia management techniques designed to develop advanced competence and proficiency in the diagnosis, treatment and longitudinal care of patients with complex arrhythmias. It will also involve 6 months of training in device implantation. This may be obtained within a 3-year cardiology program if enough electrophysiology lab time is dedicated to acquiring pacemaker implantation skills plus related management and follow-up. Trainees must keep a log of their activities documenting the indication for the procedure, the device placed, and any complications, as well as a list of devices interrogated. III. Portfolio Accomplishments At the conclusion of each month on the electrophysiology service, the fellow will have completed the following goals toward credentialing of clinical competence: 1. Completion of reading the core references (see below), and documenting this in his/her log. 2. Primary operator on the interrogation and programming of at least 5 pacemakers and defibrillators (which should encompass at least 2 major device vendors), to be documented in his/her log In addition, as part of the fellows electrophysiology portfolio, the fellow should initiate and maintain, documentation of all temporary pacemakers and DC cardioversions he /she has performed. The fellow is expected to perform 10 DC cardioversions and 10 temporary pacemaker insertions over the course of the three year fellowship. Core References: Month 1 1. The anatomy and physiology of the conduction system and basic cellular electrophysiology including arrhythmia mechanisms Genesis of Cardiac Arrhythmias: Electrophysiological Considerations. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 27, pages 653-687 3 2. Pharmacokinetics, actions and toxicity of antiarrhythmic medications Therapy for Cardiac Arrhythmias. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 30, pages 713-736 3. Management and Anticoagulation For Arial Fibrillation ACC/AHA/ESC 2006 Guidelines for the Management of patients with Atrial Fibrillation. Circulation 2006; 114:710-739 4. Direct Current Cardioversion Therapy for Cardiac Arrhythmias. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 30, pages 736-739 5. Pacemaker timing cycles and programming. Indications for permanent and temporary pacemakers, and Implantable Cardioverter-defibrillator Treatment, including for the management of CHF Cardiac Pacemakers and Cardioverter-Defibrillators. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 31, pages 767-802 Role of implantable cardioverter-defibrillators for the primary prevention of sudden cardiac death after myocardial infarction. Podrid and Ganz http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/56215&sel ectedTitle=5~125&source=search_result Role of implantable cardioverter-defibrillators for the secondary prevention of sudden cardiac death. Podrid, Arnsdorf and Cheng. http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/46703&sel ectedTitle=4~125&source=search_result Overview of cardiac pacing in heart failure. Saxon, Kumar and Demarco http://www.utdol.com/utd/content/topic.do?topicKey=hrt_fail/22712&sele ctedTitle=15~252&source=search_result 6. Diagnosing Cardiac Arrhythmias Diagnosis of Cardiac Arrhythmias. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 29, pages 697-712 7. Indications for electrophysiologic testing Overview of Invasive Electrophysiology studies. Podrid and Ganz http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/35534&sel ectedTitle=1~62&source=search_result 4 Therapy for Cardiac Arrhythmias. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 30, pages 757-766 8. Familiarity with intracardiac tracings and catheter placement Core References: Month 2 1. Pathophysiology, evaluation and treatment of syncope/ Tilt Testing AHA/ACCF Scientific Statement on the Evaluation of Syncope. JACC Vol47, No. 2, 2006:473-84 Pathogenesis and etiology of syncope. Olshansky http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/56946&sel ectedTitle=2~316&source=search_result Evaluation of the patient with syncope. Olshansky http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/32604&sel ectedTitle=2~34&source=search_result Neurocardiogenic (vasovagal) syncope and carotid sinus hypersensitivity. Olshansky http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/57305&sel ectedTitle=3~34&source=search_result Upright tilt table testing in the evaluation of syncope. Olshansky http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/46365&sel ectedTitle=1~34&source=search_result Postural tachycardia syndrome. Freeman and Kaufman http://www.utdol.com/utd/content/topic.do?topicKey=genneuro/6430&sel ectedTitle=4~34&source=search_result 2. Pathophysiology, evaluation and treatment of sudden cardiac death Overview of sudden cardiac arrest and sudden cardiac death. Siscovick and Podrid http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/29910&sel ectedTitle=1~3791&source=search_result Pathophysiology and etiology of sudden cardiac arrest. Podrid, Arnsdorf and Cheng. http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/34030&sel ectedTitle=2~364&source=search_result Sudden cardiac death in the absence of apparent structural heart disease. Pinto and Josephson. 5 http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/47754&sel ectedTitle=3~364&source=search_result Outcome of sudden cardiac arrest. Podrid, Arnsdorf and Cheng http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/33730&sel ectedTitle=4~364&source=search_result Evaluation of the survivor of sudden cardiac arrest. Podrid, Arnsdorf and Cheng. http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/33002&sel ectedTitle=5~364&source=search_result 3. Pathophysiology, evaluation and treatment of SVT and atrial fibrillation Specific Arrhythmias: Diagnosis and Treatment. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 32, pages 810-841 4. Pathophysiology, evaluation and treatment of Non Sustained VT Nonsustained VT in the absence of apparent structural heart disease. Morton F Arnsdorf, MD, MACC http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/21687&sel ectedTitle=1~83&source=search_result Management of nonsustained ventricular tachycardia. Zimetbaum, Josephson, and Wylie http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/16544&sel ectedTitle=2~83&source=search_result Prognosis of nonsustained VT in the presence of structural heart disease. Zimetbaum, Josephson, and Wylie http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/23754&sel ectedTitle=3~83&source=search_result 5. Pathophysiology, evaluation and treatment of Sustained VT Specific Arrhythmias: Diagnosis and Treatment. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 32, pages 841-854 4. Catheter Ablation Catheter ablation of cardiac arrhythmias: Overview and technical aspects. Ganz http://www.utdol.com/utd/content/topic.do?topicKey=carrhyth/42652&sel ectedTitle=15~842&source=search_result Additional Suggested Reading: 6 The following references are provided as a starting point to the further understanding of Electrophysiology and management of arrhythmias, devices and syncope. Up to Date®, is also provided by DHMC, and is an excellent resource on virtually all topics in Electrophysiology, and is highly recommended as a resource. 1. 2. 3. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. IV: Genetics of Cardiac Arrhythmias. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 28, pages 689-695 Cardiac Arrest and Sudden Cardiac Death Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 33, pages 865-908 Hypotension and Syncope. Heart Disease. A Textbook of Cardiovascular Medicine. 7th Edition. Braunwald 2005. Chapters 34, pages 909-919 A Simplified Method to Predict Occurrence of Complete Heart Block During Acute Myocardial Infarction. G Lamas et al. AJC Vol. 57, No 15, June 1, 1986:1213-19 Desai AD, Chun S, Sung RJ. The role of intravenous amiodarone in the management of cardiac arrhythmias. Annals of Internal Medicine. 1997; 127(4):294-303. Kowey PR, Marinchak RA, Rials SJ, Filart RA. Intravenous amiodarone. Journal of the American College of Cardiology. 1997; 29(6):1190-8.12 Supraventricular Tachycardia. L. Ganz. NEJM Jan. 1995 Vol. 332 No 3: 162-73 Supraventricular Tachycardia. L. Ganz. NEJM Jan. 1995 Vol. 332 No 3: 162-73 Ventricular Premature Depolarizations and Non-sustained Ventricular Tachycardia. A. Buxton and J. Duc. Cardiac Arrhythmia: Mechanism, Diagnosis and Management. Second Edition. P. Podrid and P. Kowey. Chapter 18 pages 549-571 Sustained Monomorphic Ventricular Tachycardia. D. Martin and J.M. Wharton. Cardiac Arrhythmia: Mechanism, Diagnosis and Management. Second Edition. P. Podrid and P. Kowey. Chapter 19 page 573-601 Atrial Fibrillation. Jahangir A, et al. Cardiac Arrhythmia: Mechanism, Diagnosis and Management. Second Edition. P. Podrid and P. Kowey. Chapter 15 page 459-499 Guidelines for the Management of patients with Atrial Fibrillation. Circulation 2006; 114:700-752 Ommen SR, Odell JA, Stanton MS. Atrial arrhythmias after cardiothoracic surgery. New England Journal of Medicine. 1997; 336(20):1429-34. Zimetbaum P, Josephson ME. Evaluation of patients with palpitations. New England Journal of Medicine. 1998; 338(19):1369-73. Professionalism: In order to achieve these expectations, the fellow will have full access to an attending electrophysiologist both in the EP lab and on the wards to discuss and learn appropriate patient management. The fellow will read independently on issues that are of 7 interest (above and beyond the suggested reading) and the attending electrophysiologist will be available to supply the relevant material. The fellow's responsibilities will include: ●Performing consults ●Being responsible for admissions to the EP service ●Being responsible for rounding and writing notes on the EP service patients. ●Being the primary contact person for the house staff covering the EP service patients. ●Observing one VT study, one SVT study, and one tilt test per week. The fellow should also observe/participate in at least one of each type of pacer and ICD implantation during the month. ●Spending as much time as possible participating in pacemaker programming and troubleshooting. ●The fellow will not be responsible for placing or removing catheters or sheaths except in cases where the fellow is positioning catheters to develop competency, or on special occasions to help out the attending. Practice-Based Learning: Fellows will be given the opportunity to participate in ongoing EP research activities and quality improvement efforts. This includes those specific to the electrophysiology laboratory and arrhythmia management in other venues such as the outpatient clinics, ER and general medical floors. Systems-Based Practice, Interpersonal and Communication Skills: The electrophysiology program is integrated into the overall cardiovascular disease treatment paradigm at DHMC. As a regional center, the electrophysiology section offers unique tertiary and quaternary expertise not available at other centers in the region. Therefore, the general cardiology fellow will get insights into the role of a referral center to provide high intensity diagnostic and therapeutic interventions for appropriate patients. Further, the fellow will learn to important communication skills to relay electrophysiologic data and treatment plans to referring physicians within and outside DHMC. V: Evaluation. At the beginning of each electrophysiology rotation, the above document will be given to the fellow, along with a detailed discussion outlining the expectations, duties and functions of the fellow for the upcoming rotation. Midway through and at the end of each rotation the fellow will be given feedback as to his or her performance and knowledge base, with appropriate suggestions for improvement. At this time, solicitation of comments from the fellow for improvements to the electrophysiology program will also be elicited. This interaction is designed to foster mutual respect and facilitate an improvement of the electrophysiology program, its teaching methods, and opportunities afforded to the fellow. 8 VI. Faculty Mark Greenberg, MD. Director Clinical Electrophysiology (Board Certified Cardiology, Electrophysiology, and Pacing) Peter Holzberger, MD. Associate Director Clinical Electrophysiology (Board Certified Cardiology, Electrophysiology, Pacing and Defibrillation) Barbara Gerling, MD. Staff electrophysiologist (Board Certified Cardiology, Electrophysiology, Pacing and Defibrillation) Steven Weindling, MD. Staff pediatric electrophysiologist (Board Certified Pediatric Cardiology) Paul Steiner, MD; Staff electrophysiologist (Board Certified Cardiology, Electrophysiology) Rajbir Sangha, MD; Staff electrophysiologist Mark Kiesling, PA; Steven Holderman NP, Terry Hall, RN Mary Ann Coackley, RN