A&P I Chapter 10 Worksheet p1/7 Name:___________________________________________ Chapter 10 1) Motion results from alternating ____________________ and relaxation of muscles; the skeletal system provides leverage and a supportive framework for this movement. 2) The scientific study of muscles is known as __________________. 3) Skeletal muscle tissue is primarily attached to bones. It is ____________________ and________________________. A. action potentials B. body movements Cardiac muscle tissue forms the wall of the heart. It is striated and___________________________. C. body positions 5) Smooth (visceral) muscle tissue is located in viscera. It is _____________________________(smooth) and involuntary. E. Elasticity 6) Muscle functions are production of________________________, stabilizing______________________, ____________________ substances within the body, and generating_________________. 4) D. Contraction F. endomysium G. Epimysium H. Extensibility 7) Electrical excitability is the ability to respond to certain stimuli by producing electrical signals such as _________________(impulse). I. Fascia (3x) 8) Contractility is the ability to shorten and thicken (contract), generating _____________________to do work. K. force 9) In an __________________________contraction, the muscle develops tension but does not shorten. J. Fibers L. heat M. Involuntary 10) In an __________________________contraction, the tension remains constant while the muscle shortens. N. isometric 11) _______________________________is the ability to be extended (stretched) without damaging the tissue. P. moving O. isotonic 12) ___________________________is the ability to return to original shape after contraction or extension. Q. Mycology 13) Each skeletal muscle is a separate organ composed of cells called___________________________. S. Perimysium 14) ________________________________is a sheet or band of fibrous connective tissue that is deep to the skin and surrounds muscles and other organs of the body. U. Voluntary R. Nonstraited T. Striated 15) Superficial ______________________(or subcutaneous layer) separates muscle from skin and functions to provide a pathway for nerves and blood vessels, stores fat, insulates, and protects muscles from trauma. 16) Deep_______________________, which lines the body wall and limbs and holds muscles with similar functions together, allows free movement of muscles, carries nerves, blood vessels, and lymph vessels, and fills spaces between muscles. 17) Other connective tissue components are ___________________, covering the entire muscle;____________________, covering fasciculi; and______________________, covering individual muscle fibers; all are extensions of deep fascia. A&P I Chapter 10 Worksheet p2/7 Name:___________________________________________ 18) Tendons and aponeuroses are extensions of ________________ tissue beyond muscle cells that attach muscle to bone or other muscle. 19) A _______________________ is a cord of dense connective tissue that attaches a muscle to the periosteum of a bone. 20) An __________________________is a tendon that extends as a broad, flat layer. 21) ____________________convey impulses for muscular contraction. 22) _________________provides nutrients and oxygen for contraction. 23) During embryonic development, skeletal muscle fibers arise from ___________________________. 24) A few myoblasts persist in mature skeletal muscle as ________________________cells. 25) Skeletal muscle consists of fibers (cells) covered by a ___________________________. 26) The fibers contain T tubules and _______________________ 27) _____________________________are tiny invaginations of the sarcolemma that quickly spread the muscle action potential to all parts of the muscle fiber. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S. T. U. V. A band Aponeurosis atrophy Blood calcium ions Connective Cytoplasm Glycogen H zone hypertrophy I bands Myoblasts Myofibrils Myoglobin Nerves Sarcolemma sarcomeres (2x) Sarcoplasm Satellite T tubules Tendon Z disc 28) Sarcoplasm is the muscle cell ________________________and contains a large amount of ______________________for energy production and ________________________for oxygen storage. 29) Each fiber contains _______________________that consist of thin and thick filaments. 30) The sarcoplasmic reticulum encircles each myofibril. It is similar to smooth endoplasmic reticulum in nonmuscle cells and in the relaxed muscle stores_______________________________. 31) Muscular _____________________is a wasting away of muscles, whereas muscular _______________________________is an increase in the diameter of muscle fibers. 32) Myofibrils are composed of thick and thin filaments arranged in units called______________________________. 33) ___________________________are the basic functional units of a myofibril and show distinct dark (A band) and light (I band) areas. 34) The darker middle portion is the __________________consisting primarily of the thick filaments with some thin filaments overlapping the thick ones. 35) The lighter sides are the _____________________that consist of thin filaments only. 36) A _________________________________passes through the center of the I band. 37) A narrow ______________________in the center of each A band contains thick but no thin filaments. A&P I Chapter 10 Worksheet p3/7 Name:___________________________________________ 38) _________________________can result in torn sarcolemma, damaged myofibrils, and disrupted Z discs. A. Actin 39) Contractile _________________generate force during contraction. C. cross bridges 40) __________________________, the main component of thick filaments, functions as a motor protein. D. cytosol 41) Motor proteins push or pull their cargo to achieve movement by converting energy from ATP into _______________________ energy of motion or force. F. Exercise B. calcium ions E. Dystrophin G. M line 42) ______________________, the main component of thin filaments, connects to the myosin for the sliding together of the filaments. H. Mechanical 43) Regulatory _______________________help switch the contractions on and off. J. myosin-binding I. Myosin 44) The regulatory proteins _____________________________and ____________________________are a part of the thin filament. K. Proteins(2x) 45) In relaxed muscle, tropomysium, which in held in place by troponin, blocks the ________________________sites on actin preventing myosin from binding to actin. M. slide 46) ________________________helps a sarcomere return to its resting length after a muscle has contracted or been stretched. 47) Myomesin forms the________________________. L. sarcomere N. sliding filament O. Titin P. Tropomyosin Q. Troponin 48) ________________________reinforces the sarcolemma and helps transmit the tension generated by the sarcomeres to the tendons. 49) During muscle contraction, myosin _____________________pull on thin filaments, causing them to slide inward toward the H zone 50) Z discs come toward each other and the ____________________ shortens, but the thick and thin filaments do not change in length. 51) The sliding of filaments and shortening of sarcomeres causes the shortening of the whole muscle fiber and ultimately the entire muscle. This is called the _______________________mechanism. 52) At the beginning of contraction, the sarcoplasmic reticulum releases _______________ which bind to troponin and cause the troponin-tropomysium complex to uncover the myosin-binding sites on actin. When the binding sites are “free”, the contraction cycle begins. 53) The contraction cycle is a repeating sequence of events that causes the filaments to ___________________________. It consists of ATP hydrolysis, attachment of myosin to actin to form cross bridges, the power stroke, and detachment of myosin from actin. 54) An increase in calcium ion concentration in the ___________________________starts muscle contraction; a decrease, stops it. A&P I Chapter 10 Worksheet p4/7 Name:___________________________________________ 55) The muscle action potential releases ________________________ from the _____________________________that combine with_______________________, causing it to pull on __________________________to change its orientation, thus exposing myosin-binding sites on __________________ and allowing the actin and myosin to bind together. 56) Calcium ion active transport _________________________return calcium ions to the sarcoplasmic reticulum. A. Acetylcholine B. actin C. action potential D. Aerobic E. Anaerobic 57) ___________________________, a state of muscular rigidity following death, results from a lack of ATP to split myosin-actin cross bridges. F. calcium ions 58) The forcefulness of muscle contraction depends on the length of the ___________________________within a muscle before contraction begins. H. Diffusion 59) Muscle action potentials arise at the ________________________ (NMJ), the synapse between a somatic motor neuron and a skeletal muscle fiber. G. Creatine phosphate I. Muscle fibers J. Myoglobin K. neuromuscular junction 60) A _________________________is a region of communication between two neurons or a neuron and a target cell. L. Neurotransmitters 61) ________________________________________bridge that gap. N. pumps 62) The neurotransmitter at a NMJ is ___________________(ACh). O. Rigor mortis 63) A nerve action potential elicits a muscle ____________________ through the release of acetylcholine. P. Sarcomeres 64) ______________________________and ATP can power maximal muscle contraction for about 15 seconds and is used for maximal short bursts of energy. M. oxygen Q. sarcoplasmic reticulum R. synapse 65) Creatine phosphate is unique to __________________________. S. tropomyosin 66) The partial catabolism of glucose to generate ATP occurs in ______________________________cellular respiration. This system can provide enough energy for about 30-40 seconds of maximal muscle activity. T. troponin 67) Muscular activity lasting more than 30 seconds depends increasingly on ______________________________cellular respiration (reactions requiring oxygen). This system of ATP production involves the complete oxidation of glucose via cellular respiration (biological oxidation). 68) Muscle tissue has two sources of oxygen: ______________________from blood and release by __________________________inside muscle fibers. 69) The aerobic system will provide enough ATP for prolonged activity so long as sufficient ____________________________and nutrients are available. A&P I Chapter 10 Worksheet p5/7 Name:___________________________________________ 70) The inability of a muscle to maintain its strength of contraction or tension is called muscle_______________________; it occurs when a muscle cannot produce enough ATP to meet its needs. 71) When considering the contraction of a whole muscle, the tension it can generate depends on the number of ____________________ that are contracting in unison. A. endurance B. Fatigue C. Fibers D. Isometric E. Isotonic 72) A motor neuron and the muscle fibers it stimulates form a _______________________. F. long 73) A single motor unit may innervate as few as 10 or as many as 2,000 muscle fibers, with an average of 150 fibers being innervated by each______________________________. H. motor unit 74) A __________________________contraction is a brief contraction of all the muscle fibers in a motor unit in response to a single action potential. 75) A record of a muscle contraction is called a __________________ and includes three periods: latent, contraction, and relaxation G. motor neuron I. myogram J. recruitment K. Red muscle L. refractory period M. short 76) The _______________________is the time when a muscle has temporarily lost excitability. N. strength 77) skeletal muscles having a __________________refractory period and cardiac muscle having a ________________refractory period. P. tetanus 78) Wave ______________________is the increased strength of a contraction resulting from the application of a second stimulus before the muscle has completely relaxed after a previous stimulus. R. twitch O. summation Q. tone 79) A sustained contraction that lacks even partial relaxation between stimuli is called complete (fused)___________________. 80) The process of increasing the number of active motor units is called ________________________ (multiple motor unit summation). 81) Aerobic training builds _______________________and anaerobic training builds muscle________________________. 82) A sustained partial contraction of portions of a relaxed skeletal muscle results in a firmness known as muscle_______________. 83) ______________________contractions occur when a constant load is moved through the range of motions possible at a joint and include concentric contractions and eccentric contractions; 84) In an _______________________contraction, the muscle does not shorten but tension increases. 85) __________________________fibers have a high myoglobin content while the myoglobin content of white muscle fibers is low. A&P I Chapter 10 Worksheet p6/7 Name:___________________________________________ 86) Fiber diameter varies as do the cell’s allocations of_____________, blood capillaries, and sarcoplasmic reticulum. A. anabolic steroids 87) Most ______________________ contain a mixture of all three fiber types, their proportions varying with the usual action of the muscle. B. autorhythmic 88) Although the number of different skeletal muscle fibers does not change, the characteristics of those present can be altered by various types of________________________. D. Cardiac (2x) 89) The use of ________________________________by athletes to increase muscle size, strength, and endurance has been shown to have very serious side effects, some of which are life-threatening. F. Exercise 90) ___________________muscle tissue is found only in the heart wall 91) Cardiac muscle fibers connect to adjacent fibers by ________________________which contain desmosomes and gap junctions C. calmodulin E. dense bodies G. fibrosis H. intercalated discs I. Mitochondria J. Multiunit K. Sarcomeres 92) _______________________muscle contractions last longer than the skeletal muscle twitch due to the prolonged delivery of calcium ions from the sarcoplasmic reticulum and the extracellular fluid. L. Skeletal 93) Cardiac muscle fibers contract when stimulated by their own _______________________________fibers. N. Smooth M. Skeletal muscles O. Visceral 94) ___________________________muscle tissue is nonstriated and involuntary and is classified into two types: visceral (single unit) smooth muscle and multiunit smooth muscle. 95) ________________________________ (single unit) smooth muscle is found in the walls of hollow viscera and small blood vessels; the fibers are arranged in a network. 96) __________________________________smooth muscle is found in large blood vessels, large airways, arrector pili muscles, and the iris of the eye. The fibers operate singly rather than as a unit. 97) Sarcoplasm of smooth muscle fibers contains both thick and thin filaments which are not organized into______________________. 98) Smooth muscle fibers contain intermediate filaments which are attached to_____________________________. 99) In smooth muscle, the regulator protein that binds calcium ions in the cytosol is _______________________(in place of the role of troponin in striated muscle. 100) ______________________muscle fibers cannot divide and have limited powers of regeneration; growth after the first year is due to enlargement of existing cells, rather than an increase in the number of fibers 101) Extensive repair results in_______________________, the replacement of muscle fibers by scar tissue. A&P I Chapter 10 Worksheet p7/7 Name:___________________________________________ 102) ________________________muscle fibers have limited capacity for division and regeneration. 103) With few exceptions, muscles develop from ________________ 104) Beginning at about 30 years of age, there is a progressive loss of skeletal muscle, which is replaced by_____________________. A. Contractions B. Fat C. Fibromyalgia D. Mesoderm 105) There is also a decrease in maximal ___________________and a slowing of muscle______________________. E. Muscular dystrophies 106) Neuromuscular disease involves problems involving somatic motor neurons, neuromuscular junctions, or muscle fibers. ______________________________signifies a disease or disorder of the skeletal muscle tissue itself. F. Myasthenia gravis 107) _______________________________is an autoimmune disorder characterized by great muscular weakness and caused by antibodies directed against ACh receptors at the neuromuscular junction; more ACh receptors are affected as the disease progresses, making the muscle increasingly weaker. G. Myopathy H. Reflexes I. Smooth J. Strength 108) ____________________are inherited muscle-destroying diseases that are characterized by degeneration of individual muscle fibers, leading to progressive atrophy of the skeletal muscle. 109) _______________________is a painful, non articular rheumatic disorder that usually appears between the ages of 25 and 50. 110) Abnormal _____________________of skeletal muscle include spasm, cramp, tremor, fasciculation, and fibrillation.