The Role of Nutrition on Our Health Food and Nutrition Services www.mmhok.com 580.286.7623 Power of Protein Inside: Protein Basics 1 Amino Acids 2 Protein Structure 3 Protein Turnover 4 Protein Functions 5-6 Food Sources 7 Additional Resources 8 Special points of interest: • Varying your protein sources helps ensure proper body functioning • Proteins make us unique! • Concerned about your weight? You might be eating too much protein! Proper nutrition is made up of 6 group of nutrients. The macronutrients fats, proteins, and carbohydrates are those we need in larger amounts as they provide our bodies with energy. The micronutrients vitamins and minerals, do not provide any calories (energy) but they are critical important to maintain our health. Water or fluid is also considered an essential nutrient group. important in a multitude of body functions like providing energy/fuel, transporting vitamins, protecting organs, maintaining body temperature, and building body cells. Fat is so important that it should make up 20-35% of all the calories that we consume in a day. Where our energy comes from... Almost all the calories our bodies burn in a day comes from the carbohydrates and fat we eat. Carbohydrates (also known as sugar, blood sugar, glucose, and carbs) are nutrients found in grains, fruits, vegetables, dairy products, and beans and are specifically designed to be the perfect fuel source. Carbs are often misunderstood and falsely accused of being “fattening” which is misleading and not entirely correct. In fact, carbs are so essential to your diet that 45-65% of all your calories should be carbohydrates! Fat is often viewed as the enemy and again, this is an incorrect assumption. Fat is What are Proteins? Proteins are large complex molecules composed of chains of amino acids. There are 20 amino acids that combine in literally tens of thousands unique combinations to form different proteins. Amino acids, and thus proteins, can contain 4 atoms– carbon, hydrogen, oxygen, and nitrogen. These amino acid protein sequences play a role in just about all of the functions in our bodies. Protein helps build muscles, tissues, and bones as well as maintains fluid balance, and producing enzymes and antibodies. Amino acids are found in animal products like meat and dairy. Other abundant sources include beans, nuts, and seeds. Depending on your age and activity level, well over half of your daily calories should come from carbohydrates and fat. This simple fact surprises many people because it minimizes the need for a very popular nutrient– protein. So, if protein is not intended to be a major calorie (energy) source, what is it for? Read on and find out! The Role of Nutrition on Our Health Page 2 Essentially Awesome Amino acids (AA) are the building blocks of proteins. Scientists have identified 20 amino acids that are critical for proper human growth and development, but there could be even more! Amino acids are divided into 2 groups: the essential and non-essential. The human body cannot manufacture 9 of the AA’s so it becomes essential that they are consumed in the diet. The other 11 can be produced in the body so they are nonessential components of the diet. However, for the body to make the nonessential AA’s, a person must consume adequate amounts of the essential AA’s as they provide the ingredients. Simply put, a healthy diet should have varied protein sources to ensure adequate intake of the essential AA’s. Show Me the Science! All 20 AA’s have a very similar molecular structure, meaning they are all made up of the same atoms in slightly different arrangements. AA’s are composed of a carbon atom in the center of the molecule, an amine group containing nitrogen, an acid group with a double bond and oxygen, a hydrogen atom, and lastly, a unique side chain. Figure (a) shows a generic amino acid with all components branching off from the central carbon atom. Figure (b) illustrates the different atom arrangements in the side chair (green boxes) which results in distinctive AA’s. The components of essential AA’s consumed in our food can be used to build the nonessential AA’s. Conditionally Essential Amino Acids The essential AA’s that must be obtained in the diet can be used to produce the nonessential AAs if needed. In most people, this process works perfectly well. However, sometimes there is a problem with the way the body handles AA’s. For example, babies born with phenylketonuria cannot breakdown the essential AA phenylalanine into the nonessential AA tyrosine. Thus, phenylalanine builds up in the body without being converted and can cause brain damage. Also, tyrosine has become conditionally essential in that individual and they must obtain it in the diet. Phenylketonuria is a rare and serious condition. People diagnosed early can have fairly normal lives with proper growth and development as long as they maintain a diet very low in many common foods containing phenylalanine (dairy, beef, nuts) and use supplements to partly make up for the nutrition they lack from these foods. All US hospitals run a simple blood test shortly after a child’s birth to look for the condition. The Role of Nutrition on Our Health Page 3 How Do Amino Acids Make Proteins? Simply stated, proteins are long series of AA’s stuck together. This forms a protein chain. There are thousands of AA’s in the body at any time and of those, there are 20 unique structures. So, those can be arranged in a chain in a nearly endless combination of ways to create different proteins. This is important because protein chains of various lengths and orders of AA’s determines what the protein will ultimately function as in the body. The components of one AA’s acid group and another AA’s amine group combine in a peptide bond linking the two AA’s together. Some atoms are not needed and those are “kicked out” of the bond to join separately as a molecule of H2O (water) that our bodies can use to help maintain fluid balance. The normal healthy processes of the human body do not let much go to waste! Can My Blood Sugar Be Too Low? Protein Structure A protein’s structure has 4 levels. Primary: the sequential order of amino acids. In other words, in what order AA’s bond together. Secondary: the spiral or folded shape of the protein chain caused by the AA bonds. We all have a unique genetic code. Our genes make tiny changes to the amino acid sequences which leads to differences in our individual protein chains. This results in our distinctive physical characteristics. Tertiary and Quaternary: further folder, twisting, and bending of the protein chain. The resulting structure can be a globular shape (may form a red blood cell) or fibrous (may become part of a tendon). The Role of Nutrition on Our Health Page 4 Protein Turnover The proteins in your body are eventually used up and need to be replaced. Amino acids (the building blocks of proteins) come from two places– the food you eat and by degrading (recycling) structures in the body that contain protein chains. Your body has an Amino Acid Pool which is like temporary storage for AA’s before they are bonded together to make proteins. Humans are composed of billions of cells. Each cell contains a nucleus which houses DNA, the genetic instructions or blueprint used in the development and functioning of all known living things. It is the DNA that decides how the body will function and what biological materials will be produced. In other words, each cell has a little brain that is very aware of what our bodies need at any given time. Pretty amazing, huh? There are many functions that AA’s and proteins can be used for in the body including creating hormones, enzymes, DNA determines how to combine amino acids to build antibodies, and cell components as well as maintaining fluid specific proteins. Every single cell has the capacity to balance. Proteins can also function instruct the body to build the infinite number of protein combinations. However, that as an energy source. approach would be repetitive and wasteful. The figure below illustrates just a So, our cells have specialized in certain areas few things the body can do with to produce different proteins if and when AA’s gathered from the AA pool. they are needed. For example, all cells can produce the protein-based hormone insulin, but only the cells in your pancreas actually do. Another example is when we cut ourselves. When we bleed, DNA tells the body to build blood clotting proteins. We do not produce these proteins continuously because we do not need them all the time! The Right Stuff In order for our bodies to make the specific proteins required at any given time, all the proper AA ingredients must be available. If not, then the missing AA becomes the limiting AA and the protein is incomplete. Without a complete chain, our bodies cannot function properly and we may get sick more often, have trouble digesting food, and our cells may even start to die. It is vitally important not to just eat enough protein foods, but to eat the right kinds that contain a variety of amino acids. A “complete” or “high quality” protein food contains all 9 essential AA’s from which the body can build the other 11 nonessential AA’s. These foods are mostly animal sources like eggs, meat, and milk, although soy products are also good sources. In general, American diets are very high in protein. However, many people forget to vary their protein sources! The figure below shows complementary protein foods. The Role of Nutrition on Our Health Page 5 Protein Functions– Cell growth, repair, and maintenance Perhaps the greatest function of protein is to maintain the health of billions of body cells. The human body is in a constant state of change just to support daily functioning and protein is vital to this process. For example, red blood cells have to be replaced every 3 months and the cells lining the digestive tract are renewed every 3 days! Amino Acids from food and from recycling old protein chains make these tasks possible. Enzymes and Hormones Enzymes are proteins that are involved in numerous chemical reactions in the body. They can break apart molecules which is an essential part of digesting food. Enzymes can also build and rearrange molecules which is one way we convert and store energy in our bodies. Hormones are chemical messengers that send signals throughout the body. Some hormones are made from protein chains. These hormones are manufactured and stored until we need to use them to maintain homeostasis or balance within our bodies. When we eat carbohydrates, enzymes (proteins) begin breaking apart and rearranging the large molecules into the simple sugar known as glucose. Also called blood sugar, glucose is our primary energy source and the hormone insulin helps us to utilize that energy. Fluid Balance As protein travels, it attracts fluid and pulls this fluid out of body tissues which allows it to continue circulating throughout the body (see figure below). This is an important process because it is through fluid that we transport nutrients as well as pick up waste products for disposal. Water is a molecule made of 2 hydrogen atoms and 1 oxygen atom. Acid:Base Balance The basic processes of our bodies are always creating acids and bases. These substances are transmitted through the blood and are expelled through the lungs as we breathe out or are excreted via urine. Our bodies maintain a very stable pH balance with the help of proteins. Remember, proteins are made up of long chains of amino acids. AAs are composed of carbon, hydrogen, oxygen, and sometimes nitrogen ,and sulfur. If our blood becomes too acidic or too basic, a protein chain acts as a buffer and can sacrifice itself by donating components to bring the body back into pH balance. If a person does not consume enough protein, there is no force to attract and pull fluid out of body tissues. This can be one cause of edema or swelling of tissue due to increased fluid build up. Immune System When invaders or antigens like allergens, viruses, toxins, and bacteria attack our bodies, we fight back with protein-made antibodies. Once an antigen is detected, protein gets to work building more antibodies that attach to the invading substance and destroy it! Although the process works well, it is very slow. Antibodies take time to produce so you will normally have a cold for a couple of days before your body has a chance to create the proper army and mount a full attack against the enemy. However, once a certain antibody has been produced, the process of replicating it at a later date becomes much quicker! That is why most people only get the chicken pox once. After your body assembled a specialized antibody force for that particular virus, it quickly recognizes the invader next time and squashes it before you feel any ill effects! It is important to note that although protein fuels the production of antibodies, eating more protein when you feel a cold coming on will do nothing but provide you unnecessary calories. The Role of Nutrition on Our Health Page 6 Protein as Energy Protein does provide energy (calories). For every gram of protein, there are 4 calories of energy. Unlike carbohydrates and fat, protein is not intended to be used as a primary energy source. As you have read, protein has many other important functions and really cannot be spared to be used as energy. An unbalanced diet that lacks carbohydrates and fats will force the body to begin pulling proteins out of blood and liver and muscle tissue which is not a good thing! However, there are times when our bodies have used up our readily available stored energy. Nitrogen Balance To use proteins for energy, the body breaks the amine group off of the amino acid. The nitrogen becomes a waste product and is excreted in the urine. The body can then rearrange the other components to form glucose, an energy source. The remaining protein components cannot be recycled back into the AA pool once broken in this way. The nitrogen content of urine and feces can actually be measured to determine whether a person has a balanced protein intake versus protein output. Nitrogen is excreted when proteins are used for energy and when protein components are recycled back into the AA pool. Based on the nitrogen content of your diet and the nitrogen excreted from your body, lab tests can show if you are gaining protein (building tissues, growing, pregnant, post-illness), losing nitrogen (poor diet, illness, starvation), or are in balance. An adult should ideally be in protein balance. How Much Protein Should We Eat? Proper protein intake depends on your age, activity level, and health status. An average adult requires 0.8 grams of protein per kilogram (kg) of their body weight. Protein needs (grams) 100 pounds (45 kg) 36 125 pounds (57 kg) 46 150 pounds (68 kg) 54 175 pounds (80 kg) 64 200 pounds (91 kg) 73 250 pounds (114 kg) 60-70* 300 pounds (136 kg) 60-70* *assuming obesity status where weight loss is recommended An easier way to think of it is that you need anywhere from 10-35% of your calories as protein. Most of us only need about 10% of our calories to come from protein sources. People who are building tissues like children, adolescents, and pregnant women need closer to the 35% range. Vegetarians need more protein because amino acids from plant sources are not processed by the body as efficiently as those from meat products. Athletes need more protein because their tissues require increased levels of oxygen. Hemoglobin, a protein, transports that oxygen to the cells. Regular exercise also damages and then repairs tissues which requires protein. Do you or your athletic children need to add protein to your diet? Probably not. Many Americans overeat protein by about 50%. Unless your child is in a sport where a certain weight class or body type must be maintained, they probably get plenty of protein in their diet. There is no need to treat your son’s basketball team to steak dinners! Too Much Protein? Eating too many calories regardless of their source (carbohydrates, fats, or proteins) will ultimately end with unhealthy weight gain. Excess calories have to be stored, after all! But, overconsumption of protein can also contribute to heart disease and high cholesterol. Most Americans over consume protein from meat sources which are often high in saturated fats and cholesterol– not a good combination. Animal products also contain certain AA’s that disrupt the natural acid:base balance. To buffer these acids, calcium, a base, is pulled out of our bones which may cause bone loss leading to osteoporosis. People who already have or are prone to kidney disease should be conscious of protein foods and limit intake to the recommended amount (see chart at left). The Role of Nutrition on Our Health Page 7 Protein Food Sources Protein is not difficult to find in our foods. Remember, the average woman needs about 50 grams of protein and the average man needs around 60 grams per day. Use these charts to help you get an idea of how much protein you are eating. You might be surprised just how quickly it adds up! Helpful tips: 1 ounce is a cupped palm of food. 3 ounces is the size of your palm or the size of a deck of cards. 8 ounces is a cup. 1 cup is about the size of an average adult fist. The Role of Nutrition on Our Health 1301 E Lincoln Rd Idabel, OK 74745 Phone: 580.286.7623 Page 8 McCurtain Memorial Hospital was originally established in 1954 and exists to provide excellence in healthcare. Our vision is to be the healthcare provider of choice in our region. We are proud to be working for a healthier community. We understand that actions speak louder than words and that is why we take our mission and vision seriously. We are always striving to improve our services and we value your feedback. Resources: McCurtain Memorial Hospital: local phone: 580.286.7623 Toll free: 1800.867.1182 http://www.mmhok.com Be sure to “like” us on Facebook! McCurtain Memorial Wellness Center: Information on the hospital’s on-site gym and wellness center. Ken Moore, ATC/LAT, Director of Wellness and Community Health- 580-208-3179 wcd@mmhok.com NOTES: ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ Abby Bridges, RD/LD, MS