Introductory Biochemistry (BCMB/BIOL/CHEM 3100) BCMB 3100 Fall Semester 2013 9:05 AM, Room C127 Life Sciences Building Instructors: Dr. John M. Brewer1 A310 Life Sciences TEL 542-1773 EMAIL: brewer@bmb.uga.edu Dr. Russell W. Carlson2 CCRC Building, 315 Riverbend Rd. TEL 542-4439 EMAIL: rcarlson@ccrc.uga.edu Objective:Theobjectiveofthiscourseistointroduceyoutothechemistryoflifeandprovideabasisfor furtherstudiesinbiologicalsciences.Thecoursematerialincludesthestructureandfunctionofbiological molecules,enzymologyandmetabolismandbioenergetics.Thecoursesyllabusisageneralplanforthe course;deviationsannouncedtotheclassbytheinstructormaybenecessary. Prerequisites:(CHEM2211orCHEM2311HorCHEM2411)and(CHEM 2211LorCHEM2311LorCHEM2411L). Text: BIOCHEMISTRY A Short Course (second edition), Tymoczko, Berg, and Stryer; Freeman and Company. Lecture and Exam Schedule: Dates Subject 8/12,14 8/16,19,21,23,26 8/28,30; 9/4,6 Reading Assignment Introduction to Biochemistry1 Amino Acids & Proteins1 Enzymes & Mechanisms of Action1 Chap. 1-2 (pgs: 1-32) Chap. 3-5 (pgs: 33-90) Chap. 6-9 (pgs: 91-154) EXAM I – September 9 9/11,13,16,18 9/20,23 9/25,27,30 10/2,4 Cofactors, Bioenergetics & Turnover of ATP1 Carbohydrates Glycolysis, Gluconeogenesis, The Pentose Phosphate Pathway, & Glycogen Metabolism1 Citric Acid Cycle1 Chap. 15 (pgs: 247-268) Chap. 10 (pgs: 155-178) Chap. 16-17; 24-26 (pgs: 269314; 421-462) Chap. 18-19 (pgs: 315-346) (Oct. 17—withdrawal deadline date.) EXAM II – October 7 10/9,11,14 10/16,18 10/21,23,25 10/28,30 Electron Transport and ATP Synthesis2 Photosynthesis2 Lipids and Biological Membranes2 Fatty Acid & Lipid Metabolism2 Chap. 20-21 (pgs: 347-386) Chap. 22-23 (pgs: 387-420) Chap. 11-13 (pgs: 179-234) Chap. 27-29 (pgs: 463-520) EXAM III – November 4 11/6,8,11,13 11/15,18,20,22; 12/2,3* Nucleic Acids and DNA Metabolism2 RNA Metabolism and Protein Synthesis2 Chap. 33-35 (pgs: 575-626) Chap. 36, 38-40. (pgs. 627644, 661-708) EXAM IV– Wednesday, December 11 8:00 – 11:00 AM Attendance:Attendanceismandatory.Examsquestionswillbetakenfrominformationcoveredduring lectureaswellastheassignedreadingmaterial.Itisveryimportantthatyouattendlectureandtakegood notes.Eachlecturewillbeeasierforyoutounderstandifthesectionwearediscussingisreadpriortoclass. Youwillberesponsibleforallannouncementsmadeinclass.Arriveontimeandavoidleavingearly.Turnoff cellphones.Intheeventofweatherrelatedcancellationofclasses,theschedulewillpickupthesequenceof lecturesasclassesresume.Ifwehavecoveredallmaterialforanexam,theexamwillbegivenonthefirstday back. AcademicHonesty:Allacademicworkmustmeetthestandardscontainedin“ACultureofHonesty.” Studentsareresponsibleforinformingthemselvesaboutthosestandardsbeforeperforminganyacademic work.Thepolicycanbefoundathttp://www.uga.edu/honesty/.Minimumsanctionsforviolationsof“A CulutreofHonesty”willbeagradeofFinthecourseandtranscriptnotation. CourseWebsites:Dr.Carlsonwillbeusinghispersonalwebsitethroughouthissectionofthe course.Hiscoursepageis:http://www.ccrc.uga.edu/personnel/index.php?uid=22&personnel=Tenure‐ Track%20Faculty Review/Help Sessions: Each Wednesday evening from 5:00 to 5:50 PM in Rm C127. The first of these sessions will be begin on August 14, and the last on November 20. These sessions will be used to review material, answer questions, and go over the assigned problem sets. Grading: Therewillbe4‐50minuteexamsgiventhroughoutthesemester. Exam IV will cover only the last section of material. The four exams will be equally weighted.Make‐upexamswillcomefromanexambankand maynotreflectthematerialemphasizedinlecture.AWRITTENEXCUSEisREQUIREDforallmakeupexams. ExamswillNOTbegivenearly.Ifyoubelievetherehavebeengradingerrorsonyourexamsyouhaveone weekfromthedatetheexamsarereturnedtocontactusforgradechanges.Nogradeswillbechangedafter thisdate.ThefinalGradingScalefromFall2009wasasfollows:A93to100,A‐90to92,B+86to89,B83to 85,B‐80to82,C+76to79,C65to75,D50to64andFbelow50.Thefinalgradingscalemaydiffer. Labor Day: September 2. Fall Break: November 1. Thanksgiving: November 25-29. Please see one of us if you are interested in the honors option. *The University shall operate a Friday class schedule on Tuesday, Dec. 3. This is done to equalize the class minutes between MWF and Tu-Th classes and to provide an equal number of class meetings for courses which may meet only once per week.