Experience with Early Implementation of
CVVH in Pediatric Rhabdomyolysis
Hoover N, Thompson R, Vats A
Background: CVVH may be effective in
myoglobinuric-induced acute renal failure (MIARF). Results: Five patients (1.6-11.3 yrs)
received CVVH (120-257 hrs) for MI-ARF.
Ultrafiltration (UF) rates varied widely from a
mean of 393 to 1349 cc/hr. All five patients
regained normal renal function. Conclusions:
Institution of CVVH was associated with a rapid
decline in serum CPK. Based on the data, we
speculate early hemofiltration in patients with
impending MI-ARF may minimize renal tubular
injury.
Nancy G. Hoover, MD, Fax 404-325-6233, email
nancy.hoover@choa.org
Department of Critical Care, 1405 Clifton Road NE,
Atlanta GA, 30322
Children’s Healthcare of Atlanta at Egleston, Dept
of Pediatrics, Emory University School of
Medicine