Civil War Medicine By Chris Moulton ADVANCE Staff In 1862 Dr. Julian John Chisom, a confederate surgeon, recommended to Gen. Clifford Pemberton commander of the forces in South Carolina, that he evacuate James Island off of Charleston because he believed malaria would kill more of Pemberton men than the Union ever would. Although events like this did not significantly sway the course of the South's or the North's military fortune, disease in general did much to decimate the numbers on both sides during the Civil War. More people died from infection and disease during the four-year engagement than from the bullets themselves. According to Terry Hambrecht, MD, a research physician at the National Institutes of Health and editor of American Armamentarium Chirurgicum, a book detailing Civil War surgical instruments, roughly two people died of disease for every one that died of bullet wounds. ALTHOUGH doctors during the Civil War knew about contagion and infection, they were not aware of the role of microorganisms.1 "Civil War medicine was a lot of learn-by-doing," said Michael Rhode, archivist at the National Museum of Health and Medicine in Washington, DC. "The better doctors would have some training, but a lot were not educated. They did not know about disease theory and so no one bothered about washing their hands. However, if the doctors poured whisky over their hands the patient would more likely survive." Doctors would often use the same sponge to clean more than one patient's wounds, said Dr. Hambrecht. The Confederacy, he said, was short on sponges and would often use rags for this purpose. Occasionally they would wash the ragout in hot water, inadvertently stopping the transmission of infection from wound to wound. The Confederate doctors also would sometimes run out of suture material for sewing wounds and as a substitute would use horse hair. This was also slightly advantageous to them since to make the horse hair pliable they would boil it in hot water. "Laudable pus" was the term physicians of the day applied to a certain kind of pus which they felt was good. In a sense the surgeons were correct to believe this, since pus represents evidence that the white blood cells are doing their job, Dr. Hambrecht noted. MOST SURGEONS THOUGHT that probing wounds with their fingers was a better way to trace the track of a bullet wound than the use of an instrument. "They did not recognize the danger of introducing microscopic foreign bodies into the wounds," said Dr, Hambrecht. Some hospitals during the Civil War would use old dressings for use on new patients.1 Considerable abuse resulted from the government's failure to supply enough emergency dressings. Soldiers would use unclean handkerchiefs and cloth torn from their shirts for this purpose. Fevers such as tetanus, erysipelas, hospital gangrene and pyemia were another great threat to wounded soldiers, many of whom had undergone amputation. Erysipelas is believed to have been caused by Streptococcus pyogenes. Tetanus is caused by Clostrium tetani Pyemia, poisoning of the blood caused by the absorption of pyogenic microorganisms, was nearly always fatal to its victims.2 Those infected suffered from multiple abscesses, jaundice, profuse sweating, chills and fevers. Of the 2,818 reported cases of pyemia, in the Union army only 71 men recovered3. In the South the disease reportedly caused 35 percent of all deaths following amputation. TREATMENT consisted of providing a nourishing diet and the application of stimulants such as dilute sulphuric acid or quinine. Tetanus, only slightly less fatal than pyernia, was much rarer.1 It was uneven in its distribution. Whole battles could be fought that were free of the bacterial infection, while other engagements would result in numerous wounded sick with the disease. Tetanus at the time was attributed to many causes—night air and drafts, exposure to excessive heat or cold, injuries to nerves while a surgeon probed and operated, bone splinters or bandages and neglect of thorough and early cleansing of a wound. Although they did not know it during the Civil War, Clostridium is frequently found in the soil. It can be carried in the intestines of horses so that ground fertilized by horse manure is likely to be contaminated. This is possibly the explanation why so many cases of tetanus appeared among injured Union soldiers after the Battle of the Wilderness, Wounded soldiers belonging to the Army of the Potomac were put to bed in stables in Fredericksburg after the famous battle ALTHOUGH bearing a far lesser fatality rate than pyemia, hospital gangrene was the most feared surgical disease. Starting as a small black spot, gangrene can appear on a healing wound and spread rapidly across a patient's leg or arm resulting in extensive tissue death. The tissue death would result from the cessation of blood circulation or by bacterial infection. Records show that 2,642 cases of hospital gangrene afflicted soldiers of the Civil War.3 Approaches to treating the disease varied, depending upon the surgeon. Some preferred using the knife, while others preferred corrosive chemicals such as nitric acid. Miscellaneous remedies such as chlorine, turpentine, yeast and charcoal were also employed. By the time of the Battle of the Wilderness in 1864, however, doctor in the Union had discovered that bromine served as an effective remedy to hospital gangrene. Erysipelas was characterized by reddening and swelling of the affected areas. It can be transmitted by dirty instruments, dressings and doctor's hands. Death from the disease was about 8 percent. However it was known to assume a more lethal form during epidemics. Besides drainage and cold water treatment of the lesions patients were given nourishing food and much whisky. Hemorrhages of smaller vessels were packed with what a modern military surgeon has described as "astringent, coagulant and generally harmful drugs."' In the North the styptic most often used was persulphate of iron1. In one recorded case nurses working in four-hour shifts pressed their thumbs to a bleeding artery for a week to control hemorrhaging in a Union hospital, while another tale is told of a similar nurse relay in a Confederate hospital lasting three weeks. Although the Civil War took place before Lister published his first paper on antisepsis in 1867, Civil War surgeons did use carbolic acid and a number of other substances which today are known as antiseptics. However, the surgeons did not know to use the antiseptics until the wound had reached a high level of infection. While Union surgeons considered maggots to be a pest that badly needed to be cleaned from the wounds, the Confederates discovered that the grubs could actually be beneficial. Maggots scavenge the tissue, eating away diseased matter in a wound, leaving the clean and healthy tissue behind. CIVIL WAR surgeons used chloroform and ether during operations.4 Chloroform, because of its smaller bulk, speedy action and noninflammability was preferred to ether. A third agent, a mixture of the two, was also used. During the war about 80,000 administrations of general anaesthetics were given, 76 percent of which were chloroform. Only about 43 people died from anaesthetic during the war. The low death rate from anaesthetics possibly was due to the method of administration. Dropped on to a folded cloth or towel or onto a paper cone ' with a sponge in its apex, the anaesthetic would be gradually lowered toward the patient's nose and mouth and withdrawn on full anaesthetic. Since most operations were performed in tents or outdoors, fresh air would mix with the anaesthetic vapors. Aside from the infections that afflicted those with wounds, there were several diseases ravaging the men in blue and grey. While many diseases were recognized clinically, no one knew how they were transmitted, caused or how to control them.4 The one exception to this was smallpox. Although the treatment for this disease was not completely effective, Civil War doctors could modify the epidemiology of the sickness. Vaccination was used to prevent smallpox, explained Dr. Hambrecht, Cowpox is caused by a virus very similar to smallpox, but cowpox produces only a mild disease in humans. Soldiers who are inoculated with the relatively harmless cowpox virus, became immune to smallpox. In the Civil War, this was done by placing a cowpox scab from a person with cowpox or from a previously vaccinated person on the skin of the person to be inoculated and then poking the scab with a sharp, pointed instrument such as a needle. This introduced some of the virus beneath the skin, resulting in immunity. Dysentery and diarrhea were among the most common diseases during the Civil War,4 The impact of these diseases on the Federal army is shown by the number of cases—1,739,135. And the death rate increased during the war. The death rate per 1,000 mean strength increased from 4.2 in the first year to 21,3 in the last year. Information on the death rates from dysentery and diarrhea is not available for the Confederate Army, but there is evidence to suggest that it was at least as common in the South. ALTHOUGH there were numerous treatments for enteritis, none were specific and in all likelihood none were effective. Since the disease was selflimited, many different treatments seemed beneficial for acute diarrhea. Among the many remedies used was sulphate of magnesia which one surgeon thought to be effective in the Corinth campaign of 1862. Supposedly, 150 barrels of it were ordered by the medical director of Grant's command. The second most common camp disease was malaria. Present in all military districts, it was predominant in those that were warm and wet. Mostly striking in September and October, the disease could hit earlier in the year as well The most severe outbreaks of malaria occurred in the South where there was a combination of much water and a long warm season. Although malaria was common in the South, the Northern troops had encountered the disease before. However, it was the Union regiments from the New England states, Michigan, Wisconsin and Minnesota that were hit the hardest. According to Dr. Hambrecht, malaria was thought to be caused by miasmas, the poisonous atmosphere believed to rise from swamps. They did not know the mosquitoes from the swamps were carrying the disease. Perhaps the most effective therapy during the Civil War was the use of quinine. It was also used as a prophalactic for malaria. Typhoid fever was an important threat to the troops.4 Its occurrence was attributed to prolonged stays in unsanitary camps. Other diseases that affected the soldiers were measles, mumps and pneumonia, with the latter thought to be caused by bad air. If a building was not well ventilated, it was thought this could cause disease. Indeed, soldiers in tent hospitals fared better than those in wooden hospitals. The doctors of the time did not know that while the tents were moved often leaving the microbes in the ground behind, the wood in more permanent hospitals became contaminated with the many different bacteria and so posed a continued threat to the convalescing troops. It was also true that soldiers from rural areas were more likely to be stricken with disease than their urban counterparts. Those from the city had been exposed to more childhood diseases and had developed immunity to some of them, while those from the countryside did not tend to have this advantage. THE MYSTERY and uncertainty surrounding the fight against disease is summed up by a volunteer who committed to print his views on the subject when he wrote from Harper's Ferry, in November, 1861, where his regiment was stricken with illness:4 I hope we shall steadily improve. There is a hopeless desperation chilling one when engaged in a contest with disease. The unseen malaria has such an advantage in the fight I had rather meet anything for the regiment than the enemy who surprised us in our former camping-ground and who seems hardly yet to have given up beat... A week on a high piece of ground three miles from the river would put us all on our feet again. But as long as the morning sun rises only to quicken the fatal exhalations from this pestilential Potomac, and the evening dews fall only to rise again with fever in their breath, the contest is unequal and the victory uncertain. Hospitals during the Civil War were divided into three types of treatment facilities. Behind the battlefield, among the troops in the rear was the field dispensary. Here emergency bandages were applied and splints placed on broken legs, according to Dr. Hambrecht, the Civil War historian. Major hemorrhages were stopped and occasionally tourniquets would be applied. The wounded were then loaded on ambulances, which were either two-or four-wheel carts or wagons. The two-wheeled wagons were said to cause more pain because they tended to rock. SITUATED A mile or so from the battlefield was the field hospital Here amputations were performed, wounds explored and foreign bodies removed. Finally, there were the general hospitals located in the cities where the wounded were sent for long-term care. As the war developed the medical corps in the South were required to move their hospitals more often. When Sherman's army marched through Georgia, the South's general hospitals were constantly being moved, said Dr. Hambrecht. Medically speaking, many opportunities for important discoveries and advances in the Civil War had been missed. Only limited advances were made in diagnosing, classifying or treating diseases.4 But the stage was set for the major breakthrough to be produced by the germ theory and the concept of antisepsis which were soon to follow. Obviously, the Civil War was not fought just on the battlefields against enemy soldiers, but also in hospital wards and surgical tents against the scourge of disease, gangrene and infected amputations. References L Adams, George, Doctors in Blue, 1952. New York: Henry Schuman. Cunningham, H.H., Doctors in Gray, 1958. New York: Louisiana State University Press. Brooks, Stewart, Civil War Medicine, 1966. Springfield, IL: Charles C. Thomas. Steiner, Paul E., Disease in the Civil War 1968. Springfield, IL: Charles C. Thomas.