AL-ISRA UNIVERSITY COLLEGE OF PHARMACY PHARMACOLOGY-II1 (501363) (3 Cr.Hrs) COURSE OUTLINE 2nd Sem. 2012/2013 Course description:- The purpose of this course is to study endogenous substances, drugs & chemicals that have actions significant for the health & well- being of man; drugs used in chemotherapy of infection & cancer, hormones & their antagonists, immunosuppressant agents, Nutritional support products and drugs for obesity. In this part of pharmacology students study drugs affect: Drug Use during Pregnancy and Lactation, Neonates, Children and Geriatrics pharmacology, drugs for patients with renal and hepatic diseases, drugs Interactions and adverse drug reactions. Textbooks: 1. Basic & Clinical Pharmacology B.G. Katzung (11th Ed).2010 2. Lippincott’s Pharmacology. M.J. Mycek, Sh.B. Gertner M.P. Perper (5rd Edition).2012 3. Modern Pharmacology with Clinical Application. Charles R. Craig, Robert E. Stitzel (9th Ed). 2008 Reference: Books 1. The Pharmacological Basics of Therapeutics Goodman & Gilman (12th Edition) 2011. 2. Gennaro A: Remington's Pharmaceutical Sciences, 22nd ed Mack Co., Easton. Pennsylvania 2010 Evaluation: 1. Examinations 1st Exam 2nd Exam Final Exam Activity & reports Lect. No. 1 2 3 4 5 6 25% 25% 40% 10% Topics Chemotherapy: Introduction, Classification Bacterial resistance to Antibiotics Sulfonamides of Antimicrobial agent, Beta- Lactam Antibiotics, Penicillin, Cephalosporin, other β- Lactam Antibiotics Protein Synthesis Inhibitors, Tetracycline, Chloramphenicol, Macrolide, Erythromycin, Clarithromycin, Azithromycin, Clindamycin 7 8. 9 10 11 12 13 14 15 16 17 18 19 20 21 Quinolones, Urinary Antiseptic, Antimycobacteral drugs, Rifampicin Chemotherapy of Leprosy Antifungal Drugs Antiprotozoal Drugs, Antimalarial Drugs Antheliminithics Drugs Antiviral Drugs Antiviral Drugs continue Chemotherapy of Neoplastic diseases, Anticancer Drugs Anticancer Drugs continue Immunomodulating Drugs Immunostimulant Drugs Immunosuppressants Nutritional Support Products and Drugs for Obesity 22 NUTRITIONAL DEFICIENCY STATES 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 Overweight and obesity Vitamins Water soluble vitamins Fat-soluble vitamins Minerals and Electrolytes OCULAR PHARMACOLOGY Second exam Drug Use During Pregnancy and Lactation Neonates and Children Geriatric Pharmacology Drugs for patients with Renal Diseases Drugs for patients with Hepatic Diseases Drugs Interactions Drugs Interactions continue Drugs Interactions continue Adverse drug Reactions Diagnostic Drugs Recently Approved Drugs Miscellaneous Drugs Review Lecture by evaluation Review Lecture by evaluation Review Lecture by evaluation Final exam