MODULE SPECIFICATION TEMPLATE
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The title of the module
Metabolism and Enzymes (BI593)
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The Department which will be responsible for management of the module
Business and General Education. Mid Kent College
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The Start Date of the Module
September 08
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The cohort of students (onwards) to which the module will be applicable.
September 07
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The number of students expected to take the module
15
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Modules to be withdrawn on the introduction of this proposed module and
consultation with other relevant Departments and Faculties regarding the
withdrawal
None
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The level of the module (e.g. Certificate [C], Intermediate [I], Honours [H]
or Postgraduate [M])
Intermediate
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The number of credits which the module represents
15
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Which term(s) the module is to be taught in (or other teaching pattern)
Autumn and Spring
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Prerequisite and co-requisite modules
None
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The programmes of study to which the module contributes
Foundation Degree in Life Science Laboratory Technology and Biomanufacturing
The intended subject specific learning outcomes and, as appropriate, their
relationship to programme learning outcomes
On completing this module students will be able to;
1. Describe basic metabolic pathways, anabolic and catabolic (Programme
outcomes A2 B1 C1)
2. Have knowledge and understanding of the role of energy conversions in cell
metabolism and discuss cellular energetics in relation to glycolysis, aerobic
oxidation and photosynthesis (Programme outcomes A2 B1)
3. Appreciate the role of nucleic acids and the genetic code in the synthesis of
macromolecules (Programme outcomes A2 B1)
4. Appreciate that enzymes are proteins whose molecular structure determines
their function (Programme outcomes A2 B1)
5. Discuss human metabolic disorders related to altered amino acid metabolism
(Programme outcomes A2 C1)
6. Have knowledge of drug-enzyme interactions (Programme outcomes A2)
7. Undertake experiments in enzyme kinetics in a skilled reflective
manner(Programme outcomes A 2,3 B2,3,4,5 C 1,2,3,4,6,7 C2,5,)
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The intended generic learning outcomes and, as appropriate, their
relationship to programme learning outcomes
i. Undertake skilled reflective laboratory practice
(Programme outcomes A2,3)
ii. Interpret and evaluate data (Programme outcomes A 1,2 B
1,2,3,4)
iii. Analyse and synthesise data (Programme outcomes B1,2,3,4,5)
iv. Written and oral communication (Programme outcomes D
1,2,5,7,8,9 )
v. Problem solving (Programme outcomes A3 B3)
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A synopsis of the curriculum
Lectures:
Topics covered in lectures will introduce the role of enzymes in the chemical
reactions of cellular metabolism. Lecture topics will include;
The characteristics of enzymes as biological catalysts, enzyme kinetics, enzyme
classification, regulation of enzyme activity, anabolic and catabolic metabolic
pathways, roles of ATP/NAD+/FAD, aerobic respiration, oxidative phosphorylation,
products of glycolysis catabolism, anabolic formation of glucose, role of glycogen its
formation and breakdown, fat metabolism and fat as an energy store, photosynthesis
and its role in uptake of carbon dioxide and primary production of carbohydrate, the
role of nucleic acids in synthesis of macromolecules, particularly proteins and
enzymes, human metabolic diseases related to altered amino acid metabolism and
protein structure, enzyme/drug interactions
Practicals
Practical classes will be integrated into the lectures and will allow students to study
enzyme kinetics, rates of reaction and effects of enzyme and substrate concentration
and factors that effect enzyme activity including effect of inhibitors. These will
consolidate students’ knowledge and understanding while allowing students to
develop scientific enquiry, project management and methodology skills
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Indicative Reading List
Price, N.C. and Stevens, L. (2001) Fundamentals of Enzymology. 3rd Edition.
Oxford University Press
Nelson, D.L. and Cox, M. (2004) Lehninger, Principles of Biochemistry. 4th Edition
Berg, J.M., Tymoczko, J.L. and Stryer, L. (2006) Biochemistry: International
Edition
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Learning and Teaching Methods, including the nature and number of
contact hours and the total study hours which will be expected of students,
and how these relate to achievement of the intended learning outcomes
The module is taught using a combination of lectures, practicals and workshops. The
lectures teach the theoretical background to metabolism and the role of ATP and
enzymes. The theory of enzyme kinetics will be underpinned by extensive practical
work and workshops will enable students to address the mathematical calculations
needed to find rates of reaction and to transform data
Lectures: 30h; Practicals: 30h; workshops: 5h. Self study, calculations, reading on the
topic 40h, revision: 45h
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Assessment methods and how these relate to testing achievement of the
intended learning outcomes
This module will be assessed by coursework assignments throughout the module
followed by an end of unit examination. Students will be able to gain feedback on
their learning and skills and improve their understanding and competence as the
module progresses. Students will begin to manage their own practical work and
demonstrate reflective practice in analysing and evaluating their work.
End of unit examination (25%) (subject specific outcomes 1,2,3,4,5,6 and generic
outcomes 3,4)
Practical write ups (25%) (subject specific outcomes 4,7 and generic outcomes
1,2,3,4)
Assessed practical carried out under examination conditions (25%) (subject specific
outcomes 4,7 and generic outcomes 1,2,3,4,5)
Short answer tests (25%) (subject specific outcomes 1,2,3,4,5,6 and generic outcomes
4)
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Implications for learning resources, including staff, library, IT and space
The module will be taught at the Kent Science Resource Centre which will have
modern well equipped laboratories, and purpose built teaching facilities. Students
will be expected to have access to IT equipment (computer). Some materials will be
available on-line
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A statement confirming that, as far as can be reasonably anticipated, the
curriculum, learning and teaching methods and forms of assessment do not
present any non-justifiable disadvantage to students with disabilities
As far as can be reasonably anticipated the curriculum, learning and teaching
methods and forms of assessment do not present any justifiable disadvantage to
students with disabilities
If the module is part of a programme in an Associate College, please complete
the following:
20. Associate College:
Mid Kent College OF H & Fe
21. University Department (for cognate programmes) or Faculty (for non-cognate
programmes) responsible for the programme: