CHAPTER 1 - The Cell Cycle (part 1) How do organisms grow? How do broken bones mend? How do people age? What is cancer? How do organisms make more of themselves? The basic unit of life Cell Theory Technological advancements such as improved microscopes have helped to study living things in detail Cell theory are: Inside the basic unit of life – the cell Numerous membrane bound organelles, that perform specific functions Nucleus – bounded by double-layered porous membrane = nuclear membrane keeps the cell’s genetic material (DNA – deoxyribonucleic Acid) DNA – forms long strands of chromatin throughout nucleus - Nucleolus – Jelly-like material = cytoplasm enclosded by cell membrane – supports nucleus and other organelles Endoplasmic reticulum – Mitochondria transform energy for cell Golgi bodies – Vacuoles – Lysosomes – So what’s the difference? Plant cells – Plant cells – Understanding the Cell Cycle Humans begin as a single cell Adults – One cell – divided into two – two becomes four and so on Each new cell must have a complete nucleus (complete set of DNA) = mitosis Before it can begin, nucleus must make a copy of itself (chromatin) = 2 sets of DNA = replication After replication – The Cell Cycle (part 2) Phases of Mitosis in an Animal Cell Prophase – Metaphase – Anaphase – Telophase – complete set of chromosomes at each pole of cell, spindle fibers disappear, nuclear membrane forms around each set of chromosoms Nucleolus appears within each nucleus, single stranded chromosomes uncoil into thin strands of chromatin = 2 nuclei in one cell (itself ready to divide) Cell division At the end of mitosis = 1 cell with 2 identical nuclei Animal cells – the cell membrane pinches in near the middle of the cell, dividing the cytoplasm into 2 new cells Plant cells – In both – each new division is an exact copy of the original Number of chromosomes in nucleus of each cell is the same number in the original cell Interphase Greater portion of time spent for a cell is called interphase (between) Used to be thought as an inactive period however now we know differently The Cell Cycle (part 3) Cell cycle ensures that number of chromosomes in nuclei of your body remains constant Chromosomes vary from species to species Dogs = 78 chromosomes, tomato plants have 24, humans have 46 While growing, mitosis and cell division add to total number of cells in body Regeneration and Aging Cut skin – usually heal in short amount of time Bone breaks – take longer This is because of mitosis – capable of repairing injured tissue Repair of injured cells or making of lost body parts = regeneration Aging Collect several product advertisements from magazines that use the word “aging” What do the advertisements claim the products will do? Base on what you know about aging, assess the credibility of each ad Do some have any scientific merit? Make a poster to display your results Cancer – the cell way out of control Cells begins to divide uncontrollably = cancer Interferes with surrounding cells and disrupts their ability to function, stock piles on top of others which results in a tumour or lump in one area Some cases, the cancerous cells move to other parts of body and grow and divide uncontrollably, consume all of the oxygen and nutrients Tobacco, asbestos, chemicals, some viruses, radioactivity and ultraviolet radiation have all been linked to cancer in humans Asexual Reproduction in Bacteria, Protists, Fungi and Animals Mitosis and cell division are the basis for asexual reproduction Asexual reproduction – Bacteria – kindgom Monera, unicellular organisms without a true nucleus – Reproduce asexually through binary fission – parent cell divides so that each new cell contains a single chromosome carrying complete DNA identical to that of the parent Unicellular organisms in kingdom Protista, for example the amoeba Molds, yeasts, mushrooms are a part of the Fungi kingdom Bodies consist of many thin hyphae which grow over the surface and other organisms to receive food Fragmentation – Budding – Spore – moulds do this in which a spore (reproductive cell) grows into a new individual through mitotic division – Spores are stored in sporangium case and when they are mature, take on certain colors Asexual Reproduction in Animals Kingdom Animalia – animals divided into vertebrates (with backbones) or invertebrates (without backbones) Invertebrates – Most invertebrates – Flatworm – Some animals – sponges or hydras reproduce by budding where a cell near the base undergoes mitosis to produce a new group of cells (bud) which completes development, breaks a part and becomes a new individual The Cell Cycle (part 4) Asexual Reproduction in Plants Ability of plants to reproduce asexually and to repair themselves = mitotic cell division Asexual reproduction ensures that each new branch has same DNA as parent Meristem – Certain times – meristematic cells specialize into cells that make up roots, stems, leaves in plant Once plant structures mature – Cuttings are lengths of parent stem – used to establish offspring that are exact copies of parent = cloning (process by which identical offspring are produced from single cell or tissue) New plants from roots – meristem cells in roots divide mitotically to produce stems, leaves and other roots – dandelions, weeds New plants from stems – meristematic cells in stem divide to produce cells that will become a new plant – strawberries have runners in which new plants grow from the tips Layering – Branch of parent plant is bent down to ground and part of it covered with soil = roots will grow from the buried stem and exposed tip will grow a new shoot Grafting – Stems from plants with desirable qualities can be attached or grafted to rooted stock of similar plant Used with apples, grapes, roses