CRN 10568
Spring 2009
Instructor
Laboratory
Office
Office Phone
Dr. Don Kane
3019 Haenicke Hall
3169 Wood Hall
(269) 387-5631 don.kane @ wmich.edu Email
Class
Office Hours
TA
Lab phone
Email
TR
WF
R
9:30 PM - 10:15 PM 1260 Chem Annex
3-4
After class
3169 Wood Hall
3169 Wood Hall
Additional office hours by appointment.
Vanessa Revindran
(269) 387-5503 vanessa.revindran @ wmich.edu
Office Hours not determined until week 2.
Prerequisite: BIOS 1500/1510
Book: Book for the class:
MODERN GENETIC ANALYSIS: Integrating genes and genomes. 2nd Edition. Griffiths, Lewontin,
Gelbart & Miller.
W. H. Freeman & Co. Publishers, New York.
ISBN 0-7167-4382-5
Note: Be careful. Do not get the other Griffiths book, Introduction to Genetic Analysis.
Optional (Not stocked in the book store):
SOLUTIONS MANUAL FOR MODERN GENETIC ANALYSIS
Fixsen and Lavett
W. H. Freeman & Co. Publishers, New York.
ISBN 0-7167-4703-0
Course Objectives
1. Understand the details of Genetics. (This is NOT an overview.)
2. Show how this knowledge was and is generated through genetic experiments.
3. Introduce genetic thinking and reasoning.
4. Learn how to master a subject by understanding material (not remembering material.)

6-Jan Introduction; terms
8-Jan DNA and Genes
13-Jan Genes and Genomes
15-Jan DNA replication/cell division
20-Jan Inheritance of single genes
22-Jan Inheritance of single genes
Ch 1
Ch 2
Ch 2
Ch 4
Ch 5
Ch 5
27-Jan Midterm 1
29-Jan Gene function
3-Feb Gene function
5-Feb Recombination in Eukaryotes
10-Feb Recombination in Eukaryotes
Ch 3
Ch 3
Ch 6
Ch 6
12-Feb Recombination in Eukaryotes
17-Feb Gene interactions
Ch 6
Ch 14
19-Feb Gene interactions
24-Feb Midterm 2
Ch 14
26-Feb Recombination in Bacteria and Phage Ch 7
3-Mar spring vacation
5-Mar spring vacation
10-Mar Recombination in Bacteria and Phage Ch 7
12-Mar Recombinant DNA Ch 8
17-Mar Recombinant DNA
19-Mar Genomics
24-Mar Genomics
Ch 8
Ch 9
Ch 9
Ch 10 26-Mar Mutation and Repair of Genes
31-Mar Midterm 3
2-Apr Chromosomal Mutations Ch 11
7-Apr Mutational Dissection Ch 12
9-Apr Regulation of Prokaryotic Transcription Ch 13
14-Apr Regulation of Eukaryotic Transcription Ch 13
16-Apr Genetic Basis for Development Ch 16
21-Apr Final 8-10 AM

Grading
There will be three in-class exams and a final exam. There will also be 10 graded problem sets.
All exam material will be from in class lectures and from the problem sets.
No calculators, cell phones or other electronic devices are allowed during exams.
Midterm 1
Midterm 2
100 pts
100 pts
Midterm 3
Final
Problem Sets
100 pts
200 pts
10 pts each; total 100 pts.
Of the exams, the lowest will be dropped. If the Final is the lowest, it will only count for 100 pts.
Note: An hourly exam can only be missed with a documented medical excuse. If one misses an exam without a documented excuse, a zero is assigned and that exam cannot be dropped. THERE WILL BE
NO MAKE-UP EXAMS. IF YOU MISS AN HOURLY EXAM, THAT IS THE DROPPED GRADE
(ZERO).
The problem sets must be turned in BEFORE the beginning of the lecture when they are due; those received during or after lecture will be marked down 5 pts. All problem sets will be returned. If problem sets are scored below 5 pts, they may be returned late to make up to 5 pts, our very own “No
Homework Left Behind” policy.
Grade Scale
Percent
90-100
85-89
80-84
75-79
70-74
65-69
60-64
0-59
Letter Grade
A
BA
B
CB
C
DC
D
E
Academic Honesty
Academic Honesty: You are responsible for making yourself aware of and understanding the policies and procedures in the Undergraduate (pp. 274-276) [Graduate (pp. 25-27)] Catalog that pertain to
Academic Honesty. These policies include cheating, fabrication, falsification and forgery, multiple submission, plagiarism, complicity and computer misuse. If there is reason to believe you have been involved in academic dishonesty, you will be referred to the Office of Student Conduct. You will be

given the opportunity to review the charge(s). If you believe you are not responsible, you will have the opportunity for a hearing. You should consult with me if you are uncertain about an issue of academic honesty prior to the submission of an assignment or test.