dbGaP Genotype Curator
Computercraft seeks a computational biologist with a background in genotype analysis to work
with NCBI scientists to develop infrastructure to analyze large-scale genomic data with clinical
phenotype data. The successful candidate will work onsite at the National Center for
Biotechnology Information (NCBI) in the Genotype and Phenotype database group
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gap . This groundbreaking project is aimed to
assist scientists discover associations between genetic variants and risks for disease.
Responsibilities will include genotype analysis pipeline development, data reformatting, data
quality control, management of a relational database, data curation, and communication with
external investigators. This is an opportunity to be involved in the development of a new resource
with the potential to revolutionize human genetic disease research.
Requirements:
• Ph.D. or M.S. or sufficient experience in genetic linkage analysis and/or allelic association
studies
• Scripting experience in Perl
• Relational database experience (SQL)
• Linux/UNIX experience
• Ability to work with a team in a production environment and communicate well with NCBI
biologists and programmers as well as external scientists
• Strong interest in contributing to the development of public database resources
Other Desirable Experience:
• Human genetics
• Haplotypes
• Analysis of structural variations
• Copy number variation
• Linkage disequilibrium
• QA filtering of genotype data (HWE, non-Mendelian segregation)
• PedCheck, Aspex, MERLIN, CRIMAP
• C++
• XML/XSLT
• HTML/CGI
• Experience with dbSNP
To apply for this position or learn about other Computercraft job opportunities, please visit the
Careers section of our website: http://www.computercraft-usa.com/
Computercraft offers a competitive salary and an excellent benefits package including PPO
health insurance with 100% company paid premiums, 401K program with matching, paid time off
and holiday pay, life insurance, flexible spending and disability coverage. We offer an excellent
work life balance with a standard 40 hour work week and the chance to work alongside
accomplished scientists at NIH/NCBI.
Computercraft is an equal opportunity employer.