Lilya V. (Semeonova) Matyunina
955 Juniper St # 2128
Atlanta, GA, 30309
Ph. (404)805-3189
School of Biology
Georgia Institute of Technology
315 Ferst Dr.
Atlanta, GA, 30332
Ph. (404)385-6629
Fax (404)894-2291
e-mail lilya@gatech.edu
Education and degree:
1987 Ph.D. in Molecular Genetics
N.I. Vavilov Institute of General Genetics
Russian Academy of Sciences, Moscow, Russia.
Thesis title: "Multiple transpositions of mobile elements in Drosophila"
1981
M.S. in Biochemistry
Altay State University, Barnaul, Russia.
Professional employment:
2004- present Research Scientist II
School of Biology, Georgia Institute of Technology, Atlanta, GA, USA.
1993- 2004
Post Doctoral Associate
Department of Genetics, University of Georgia, Athens, GA, USA.
1991-1993
Post Doctoral Fellow
Institute of Gene biology, Russian Academy of Sciences, Moscow, Russia.
1988-1991
Research Assistant
Siberian Institute of Horticulture, Barnaul, Russia.
1985-1988
Research Assistant
Altay Institute of Cattle Breeding, Barnaul, Russia.
Publications:
Hill CG, Jabbari N, Matyunina LV, McDonald JF. 2014 Functional and evolutionary significance of
human microRNA seed region mutations. PLoS One. 2014 Dec 12;9(12):e115241. doi:
10.1371/journal.pone.0115241. eCollection 2014.
Hill CG, Matyunina LV, Walker D, Benigno BB, McDonald JF. 2014 Transcriptional override: a
regulatory network model of indirect responses to modulations in microRNA expression BMC Syst Biol.
2014 Mar 25;8:36. doi: 10.1186/1752-0509-8-36.
Lili LN, Matyunina LV, Walker LD, Daneker GW, McDonald JF. 2014 Evidence for the importance of
personalized molecular profiling in pancreatic cancer. Pancreas. 2014 Mar;43(2):198-211. doi:
10.1097/MPA.0000000000000020.
Ghosh D, Lili L, McGrail DJ, Matyunina LV, McDonald JF, Dawson MR. 2014 Integral role of plateletderived growth factor in mediating transforming growth factor-β1-dependent mesenchymal stem cell
stiffening. Stem Cells Dev. 2014 Feb 1;23(3):245-61.
Lili LN, Matyunina LV, Walker LD, Wells SL, Benigno BB, McDonald JF. 2013 Molecular profiling
supports the role of epithelial-to-mesenchymal transition (EMT) in ovarian cancer metastasis. J Ovarian
Res. 2013 Jul 10;6(1):49. doi: 10.1186/1757-2215-6-49.
Lili LN, Matyunina LV, Walker LD, Benigno BB, McDonald JF. 2013 Molecular profiling predicts the
existence of two functionally distinct classes of ovarian cancer stroma. Biomed Res Int. 2013;2013:846387.
doi: 10.1155/2013/846387. Epub 2013 May 9.
Shahab SW, Matyunina LV, Hill CG, Wang L, Mezencev R, Walker LD, McDonald JF. 2012 The effects
of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally
coordinated. BMC Med Genomics. 2012 Aug 1;5:33. doi: 10.1186/1755-8794-5-33.
Liu Y, Bowen NJ, Matyunina L, McDonald J, Prausnitz MR. 2012 Gene transfection enhanced by
ultrasound exposure combined with drug treatment guided by gene chip analysis. Int J Hyperthermia.
2012;28(4):349-61. doi: 10.3109/02656736.2012.669513.
Wang L, Mezencev R, Bowen NJ, Matyunina LV, McDonald JF. 2012 Isolation and characterization of
stem-like cells from a human ovarian cancer cell line. Mol Cell Biochem. 2012 Apr;363(1-2):257-68. doi:
10.1007/s11010-011-1178-6. Epub 2011 Dec 9.
Shahab SW, Matyunina LV, Mezencev R, Walker LD, Bowen NJ, Benigno BB, McDonald JF. 2011
Evidence for the complexity of microRNA-mediated regulation in ovarian cancer: a systems approach.
PLoS One. 2011;6(7):e22508. doi: 10.1371/journal.pone.0022508. Epub 2011 Jul 21.
Chen J, Wang L, Matyunina LV, Hill CG, McDonald JF. 2011 Overexpression of miR-429 induces
mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells. Gynecol Oncol. 2011
Apr;121(1):200-5. doi: 10.1016/j.ygyno.2010.12.339. Epub 2011 Jan 28.
Liu Y, Chen Y, Momin A, Shaner R, Wang E, Bowen NJ, Matyunina LV, Walker LD, McDonald JF,
Sullards MC, Merrill AH Jr. 2010 Elevation of sulfatides in ovarian cancer: an integrated transcriptomic
and lipidomic analysis including tissue-imaging mass spectrometry. Mol Cancer. 2010 Jul 12;9:186. doi:
10.1186/1476-4598-9-186.
Bowen NJ, Walker LD, Matyunina LV, Logani S, Totten KA, Benigno BB, McDonald JF. 2009 Gene
expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and
capable of serving as ovarian cancer initiating cells. BMC Med Genomics. 2009 Dec 29;2:71. doi:
10.1186/1755-8794-2-71.
Matyunina LV, Bowen NJ, McDonald JF. 2008 LTR retrotransposons and the evolution of dosage
compensation in Drosophila. BMC Mol Biol. 2008 Jun 4;9:55. doi: 10.1186/1471-2199-9-55.
Menendez L, Walker LD, Matyunina LV, Totten KA, Benigno BB, McDonald JF. 2008 Epigenetic
changes within the promoter region of the HLA-G gene in ovarian tumors. Mol Cancer. 2008 May 22;7:43.
doi: 10.1186/1476-4598-7-43.
Moreno CS, Matyunina L, Dickerson EB, Schubert N, Bowen NJ, Logani S, Benigno BB, McDonald
JF.2007. Evidence that p53-Mediated Cell-Cycle-Arrest Inhibits Chemotherapeutic Treatment of Ovarian
Carcinomas.PLoS ONEMay 16;2:e441
Menendez L, Walker D,Matyunina L.V., Dickerson E.B., Bowen N.J., Polavarapu N., Benigno B.B,
McDonald J.F.2007. Identification of candidate methylation-responsive genes in ovarian cancer.Mol
Cancer. Jan 25;6:10.
Jordan IK, MatyuninaLV, McDonald JF. 1999. Evidence for the recent horizontal
transfer of long terminal repeat retrotransposon. Proc. Natl. Acad. Sci 96:12621-12625.
Wilson S.,Matyunina LV, McDonald JF. 1998. An enhancer-like region withing the
copia untraslated leader which is variable in natural populations contains binding sites for
Drosophila regulatory proteins. Gene, 209:239-246.
McDonald JF, Matyunina LV, Wilson S, Jordan IK, Bowen NJ, and Miller WJ, 1997.
LTR retrotransposons and the evolution of eukaryotic enhacers. in Evolution and the role
of transposable elements., Genetica, 100: 3-13.
Matyunina LV, Jordan IK, and McDonald JF. 1996. Naturally occurring variation in
copia expression is due to both element (cis) and host (trans) regulatory variation. Proc.
Natl. Acd. Sci. 93: 7097-7102
Gerasimova TI, MatyuninaLV, Mizrokhi LY, Georgiev GP. 1985. Successive
transposition explosion in Drosophila melanogaster and reverse transposition of mobile
dispersed genetic elements. The EMBO Journal, 4: 3773-3779.
Matyunina LV, Gerasimova TI. 1985. Study of spontaneous sex-linked lethal mutations
in the unstable line ctMR2 of Drosophila melanogaster. DIS, 61: 119-120.
Gerasimova TI, Matyunina LV. 1985. Unstable mutations at the locus yellow induced by
the mobile element MDG2. DIS, 61: 78.
Gerasimova TI, Matyunina LV. 1985. Simultaneous reversion of three unstable alleles at
loci yellow, white, singed. DIS, 61: 77.
Matyunina LV, Mizrokhi LY, Gerasimova TI, Georgiev GP. 1985. Transposition
explosions in series of mutational transposition in Drosophila melanogaster unstable
strains. Genetika, 21: 1608-1617. (in Russian).
Gerasimova TI, Matyunina LV, Ilyin YV, Georgiev GP. 1984. Simultaneous
transpositions of different mobile elements: relation to multiple mutagenesis in
Drosophila melanogaster. MGG, 194: 517-522.
Gerasimova TI, Matyunina LV, Mizrokhi LY, Ilyin YV, Georgiev GP. 1984. Multiple
transposition events in separate germ cells in unstable strains of Drosophila
melanogaster. Genetika, 21: 1434-1443. (in Russian).
Gerasimova TI, Ilyin YV, Mizrokhi LY, Semeonova LV. 1984. Mobilization of
transposable element MDG4 by hybrid dysgenesis and resulting in appearance of
unstable alleles at cut locus in Drosophila melanogaster. MGG, 193:488-492.
Gerasimova TI, Ilyin YV, Mizrokhi LY, Semeonova LV. 1983. The direct demonstration
a mobile element MDG4 movement and it's role in unstable mutations arising in
Drosophila. Doclady AN SSSR (Proc. of Russian Ac. of Sci.) 271: 977-980. (in Russian).