Referral Guidelines for Respiratory Medicine at Hawkes Bay DHB The outpatient Respiratory Medicine Department at Hawkes Bay Hospital is comprised of specialist physicians, clinical nurse specialists, clinical physiologists, physiotherapists, outpatient nurses, and clerical staff. As a multi-professional team we assess over 3000 patients a year and offer a wide array of services including specialist assessment and management, patient education, pulmonary rehabilitation, and lung function assessment. As the primary and secondary care management of chronic disease integrates further we hope to offer leadership, guidance, and education for all aspects of respiratory disease, whether the service is being delivered in the hospital or the community. This document is set out to offer guidance on referrals to the respiratory department, suggested management prior to referral, and an overview of referral prioritisation criteria. It is based on national referral guidelines, and international respiratory society guidelines. It is not exclusive and should not be seen as an alternative to good clinical judgment. Patients with acute respiratory symptoms, or decompensation of chronic symptoms should be considered for either admission to hospital or liaison with the Respiratory Department for urgent assessment. It is helpful if referrals to the Respiratory department include adequate information for appropriate prioritisation. The minimum information we normally require is: Symptoms Co-morbidities Medication – including relevant previous medication Smoking status Occupational/environmental exposure Physical examination findings Previous lung function results Results of relevant investigations Details of previous consultations if relevant Patients being referred for specific conditions such as sleep disordered breathing or tuberculosis may require more specific information such as Epworth Sleepiness Score or TB contact details. James Curtis Respiratory Physician Hawkes Bay DHB 1 Index 1. Prioritising Respiratory Referrals to Hawkes Bay DHB Page 3 2. Diagnosis based referral guidelines Asthma COPD Bronchiectasis Lung cancer Interstitial lung disease Tuberculosis Sleep disordered breathing Pleural effusions Page 4 Page 4 Page 5 Page 5 Page 5 Page 6 Page 6 Page 6 3. Symptom based referral guidelines Chronic cough Breathlessness Thoracic pain Haemoptysis Sleepiness Abnormal chest x-ray Recurrent/persistent chest infections Page 7 Page 7 Page 7 Page 8 Page 8 Page 8 Page 8 2 Prioritising Respiratory Referrals to Hawkes Bay DHB All referrals to the Respiratory Department are prioritised by either a specialist physician or clinical nurse specialist. Urgent “when major clinical risk is present if treatment delayed” Suspected lung cancer Possible infectious tuberculosis Severe unstable asthma Significant haemoptysis Semi-urgent “major functional impairment” Severe COPD +/- complications Severe/High risk sleep disordered breathing Symptomatic interstitial lung disease Pleural effusions Asthma requiring long term steroids Suspected occupational lung disease Poorly controlled COPD/Asthma/Bronchiectasis on optimal therapy Cystic fibrosis Opportunistic infections Pulmonary vascular disease Latent TB Routine “where clinical assessment and review may be beneficial” Although we endeavour to see all routine referrals some patients may not be seen due to pressure on the service. In this event we would hope to provide at least formal lung function if appropriate and a letter of advice. Moderate sleep disordered breathing Stable asthma/COPD Pleural plaque or other stable radiological abnormality Chronic cough with normal chest x-ray Asymptomatic parenchymal lung disease Asthma/COPD diagnostic uncertainty 3 Diagnosis based referral guidelines Asthma Asthma Hawkes Bay can be an invaluable service to asthmatics and international asthma guidelines (GINA) are a useful resource on guiding therapy. Individualized treatment regimes with asthma action plans, patient education emphasizing selfmanagement, and regular support are essential. Suboptimal control despite adequate therapy may reflect coexisting disease (i.e. chronic rhinosinusitis, gastroesophogeal reflux disease, vocal cord dysfunction, and cardiac disease), smoking, occupational exposure to sensitizing agents/dusts/fumes (10% of adult asthma is work related), poor inhaler technique, and poor concordance with treatment. When to consider referral to secondary care: Difficult to control asthma Diagnosis uncertain Suspected significant co-morbidities Features of severe asthma o Frequent courses of steroids o Frequent hospital/ED attendances o Life-threatening attacks Need for hospital based lung function or patient education/support Chronic Obstructive Pulmonary Disease Although COPD is a chronic disease it is both treatable and preventable. There are a number of documents to guide best practice with the local COPD-X guidelines, the British NICE guidelines and international GOLD guidelines being the most helpful. All emphasize the need to confirm the diagnosis with spirometry (postbronchodilator FEV1/FVC ratio <70%) particularly in smokers aged >40 years with breathlessness, frequent cough/sputum, or recurrent chest infections. When to consider referral to secondary care: Diagnostic uncertainty Frequent exacerbations Difficult breathlessness Consideration for pulmonary rehabilitation Motivated patients with stable COPD suffering from moderate/severe breathlessness impacting on quality of life should be referred for pulmonary rehabilitation unless there is significant co-morbidity (unstable cardiac disease, mobility issues etc) Need for hospital based lung function or patient education/support Significant bullous disease on chest x-ray Assessment for long-term oxygen therapy Diagnosis of COPD aged <40 yrs or severe COPD (FEV1 <50% predicted) aged <50 yrs 4 Bronchiectasis Bronchiectasis is often mistaken for difficult asthma (which can co-exist) or COPD. It is characterized by chronic productive cough. Although often a result of previous infection it can reflect other underlying conditions. With adequate bronchial hygiene, regular vaccinations, and a low threshold for treating associated exacerbations with adequate antibiotics, the disease can be controlled. When to consider referral to secondary care: All patients with suspected bronchiectasis should be referred to secondary care for assessment. Lung cancer Any patient with suspected lung cancer (haemoptysis, chronic or changing cough, breathlessness, unexplained chest/shoulder pain, hoarse voice >3 weeks, weight loss, finger clubbing, cervical/supraclavicular lymphadenopathy) should have an urgent chest x-ray. Although a staging CT scan may be needed it is best arranged in secondary care to prevent delay in referral and inappropriate/inadequate scanning. When to consider referral to secondary care: All patients with suspected lung cancer should be referred for urgent assessment. These include: o Smokers/ex-smokers aged >35 years with persistent (>1 week) haemoptysis o Chest x-ray suggestive of lung cancer o Persistent hoarse voice in a smoker (consider ENT referral if chest x-ray normal) o Signs of superior vena caval obstruction o Stridor (consider ENT referral if chest x-ray normal) o High clinical suspicion of lung cancer Interstitial lung disease Symptom onset can be indolent, but progression may be rapid and x-ray changes subtle and diverse making assessment difficult. The most frequent causes are idiopathic pulmonary fibrosis, sarcoidosis, hypersensitivity pneumonitis, drug reactions (amiodarone, methotrexate, and nitrofurantoin), occupational dust exposure, and lung disease associated with connective tissue disease. When to consider referral to secondary care: All patients with interstitial lung disease should be referred for assessment 5 Tuberculosis Although the incidence of tuberculosis disease in New Zealand remains low (10/100,000) clinical suspicion and vigilance is vital to disease control. Risk factors include high deprivation, Maori and Pacific Island ethnicity, and immune suppression (steroids, diabetes, alcohol abuse, chronic kidney disease). Latent tuberculosis infection is much commoner (10% of population). It is not infectious and often doesn’t require treatment When to consider referral to secondary care: Suspected active tuberculosis disease Possible latent tuberculosis/inactive tuberculosis disease in a patient being considered for long-term immune suppressing treatments Sleep disordered breathing Sleep apnoea (characterized by loud snoring, overnight choking/gasping, and witnessed apnoeas) is common, affecting up to 20% of adults and doesn’t automatically require further investigation. However, when in combination with intrusive daytime sleepiness, difficult hypertension, heart failure, or polycythaemia significant sleep disordered breathing should be considered. Referrals for sleep disordered breathing should include information on level of daytime symptoms, work/driving related issues, co-morbidities, and BMI. Prior to referral the GP should try to identify and address sleep restriction/deprivation, weight issues, alcohol/sedative use, and treat any chronic nasal/sinus disease. When to consider referral to secondary care: Suspected sleep apnoea with associated intrusive daytime sleepiness, heart failure, difficult hypertension, or polycythaemia Suspected obesity related hypoventilation Suspected narcolepsy, periodic limb movement disorder, or other parasomnias Pleural effusions Pleural effusions can reflect a broad range of problems. All patients with a suspected pleural effusion should have a chest x-ray, and if the cause is likely to be pulmonary (i.e. not heart failure) referral to secondary care for further assessment. Referral should include information on symptoms, smoking status, occupational history, comorbidities and medication. When to consider referral to secondary care: Pleural effusions felt unlikely to be heart failure 6 Symptom based referral guidelines Chronic respiratory symptoms are common, and the cause is not always immediately clear. If referral to secondary care is felt to be appropriate the referral should include information on symptoms, co-morbidities, medication, smoking status, occupational/environmental exposure, physical examination findings, and results of relevant investigations. Chronic cough Chronic cough can be a distressing symptom and affects a large number of people. Cough lasting for >6 weeks should be investigated further with a chest x-ray. In the setting of a normal chest x-ray the causes for chronic cough are: Cough variant asthma Rhinosinusitis Gastroesophageal reflux ACE inhibitors Sequential treatment trials with a minimum of six weeks of inhaled corticosteroid; intranasal steroids +/- antihistamines; proton-pump inhibitors + lifestyle advice re: reflux; and ACEI withdrawal is advised. When to consider referral to secondary care: No response to treatment trials Chronic productive cough ?bronchiectasis Associated dyspnoea Abnormal chest x-ray Breathlessness Patient complaining of chronic breathlessness should be considered for a chest xray, spirometry, ECG, blood count, renal function and oximetry if available. When to consider referral to secondary care: Unexplained breathlessness where significant cardiac disease is felt unlikely Disproportionate/difficult breathlessness in a patient with known lung disease Need for detailed lung function (i.e. lung volumes, gas transfer) Thoracic pain Patients with persisting pleuritic/thoracic wall pain should have a chest x-ray. When to consider referral to secondary care: Pleuritic/thoracic wall pain with abnormal chest x-ray Pleuritic/thoracic wall pain with significant concern of underlying sinister disease (i.e. smoker, asbestos exposure, previous malignancy) 7 Haemoptysis Exclude epistaxis and haematemesis. All patients with haemoptysis should have a chest x-ray. When to consider referral to secondary care: Persistent (>7 days), recurrent, or significant (>25mls per cough) haemoptysis Sleepiness Excessive daytime sleepiness is common (~ 30% of the population) as is fatigue. Common causes include sleep restriction/deprivation, shift-work, ageing, depression, and chronic medical conditions including sleep disordered breathing. Patients being referred for suspected sleep disordered breathing should have attention paid to sleep hygiene, weight, alcohol/sedative use, and co-morbidities. When to consider referral to secondary care: Suspected sleep apnoea with associated intrusive daytime sleepiness, heart failure, difficult hypertension, or polycythaemia Suspected obesity related hypoventilation Suspected narcolepsy, periodic limb movement disorder, or other parasomnias Abnormal chest x-ray Chest x-ray abnormalities can reflect many underlying conditions. Comparison to previous x-rays/reports is helpful. Although further investigation with a CT may be needed this may be best arranged in secondary care to prioritise appropriately, avoid delay, and ensure the correct scan is carried out. When to consider referral to secondary care: All patients with persistent or suspicious x-ray or CT changes should be considered for referral to secondary care for further evaluation Recurrent/persistent chest infections Patients with slow to resolve symptoms of respiratory tract infection, or recurrent infections require further investigation. A chest x-ray, spirometry, sputum cultures (MC&S and AAFB) and blood count are essential. Consider treating any associated sinus disease, and identifying and treating any gastroesophogeal reflux disease. When to consider referral to secondary care: Recurrent/persistent chest infections with concern of underlying sinister pathology 8