AP Biology Lecture Guide: Chapter 11- Cell Communication Name __________________________________________________________________ 1. How do local regulators and hormones differ? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 2. Identify and describe the three parts of cell signaling. A._____________________________________________________________________________________________________ _______________________________________________________________________________________________________ B._____________________________________________________________________________________________________ _______________________________________________________________________________________________________ C._____________________________________________________________________________________________________ _______________________________________________________________________________________________________ 3. What are ligands and what do they do? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 4. Identify the structure and the main purpose/function of the 3 main receptors. G-protein ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ Tyrosine-kinase ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ Ligand-gated ion channel ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 5. Explain why G-protein-regualted pathways shut down rapidly in the absence of a signal molecule. ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 6. Give some examples of other signal receptors. ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 7. What are transcription factors? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 8. What does a protein kinase do? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 9. What does a protein phosphatase do? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 10. What is a phophorylation cascade? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 11. How does an enzyme cascade produce an amplified response to a signal molecule? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 12. What are secondary messengers? How do they work? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 13. What is CAMP? __________________________________________________________________________________________________________ ______________________________________________________________________________________________________ 14. What are scaffolding proteins? How are they beneficial? ________________________________________________________________________________________________________ ________________________________________________________________________________________________________ 15. What are the different types of cell responses that could occur? _____________________________________________________________________________________________________________ _____________________________________________________________________________________________________________