AP Biology Chapter 11: Cell Communication Use the following chart to review the major concepts of cell communication. Describe the evolution of cell signaling. Explain the process of communication between cells at greater distances. Be specific Describe how cells near each other communicate. Be specific! Generally define the stages of cellular communication. In signal reception describe the interaction between a signal molecule and a ligand. How are tyrosine-kinase receptors different from G-protein? Describe G-proteins, G-protein receptor and their roll in reception. BE SPECIFIC! Explain how tyrosine kinase and tyrosine-kinase receptors function. Explain ligand-gated ion channels and explain how they work in reception. Describe how the following function as signal receptors. Describe their structure and give example. Steroid hormones Thyroid hormones Nitric oxide How does the activated hormonereceptor protein turn on genes? What is the benefit of a multistep pathway? Describe the function of protein kinases in the transduction process. What is the function of second messengers to the signaling pathway? Describe cyclic AMP and give specific examples of how it works as a second messenger. Describe how calcium ions and inositol trisphosphate function as second messengers. Cell response to signals usually results in regulating cellular activities. List and explain specific cellular activities controlled by signals. Define and explain signal amplification Relate specificity to cell signaling. What are scaffolding proteins and what is their function? Describe how the cell cycle is regulated and discuss one consequence of abnormal regulation.* Compare the cell-signaling mechanisms of steroid hormones and protein hormones.* Cells regulate both protein synthesis and protein activity. Discuss two specific mechanisms of protein regulation in eukaryotic cells.* *Indicate portions of previous FRQs