Geneva University, Faculty of Medicine
Post-Doctoral position
Quantitative Mass Spectrometry
A 2-years post-doctoral scientist position is available at the Clinical Pathology Division in
collaboration with the Clinical Proteomics Research group of the Faculty of Medicine,
Geneva University, Switzerland (starting October 1st 2011).
The project will focus on the development and validation of SRM/MRM methods for the
quantification of specific proteins in tissues using mass spectrometry. It involves a
collaboration between the Clinical Pathology Division of the Geneva University Faculty
of medicine & Hospitals, and Roche. The specific objectives of the project are:
- to develop highly quantitative, multiplexed SRM/MRM protein assays for specific
protein targets,
- to perform analytical validation and standardize the methodology, permitting
application in a clinical environment,
- to conduct validation experiments on a cohort of patients with well annotated clinical
specimens.
Besides strong laboratory, computer, and protein mass spectrometry skills, this position
requires an ability to work in a highly collaborative environment for the benefit of
biologists, pathologists, and clinicians.
Applicants must have a Ph.D. degree in chemistry, biochemistry, pharmacy or related
disciplines with an experience in quantitative mass spectrometry-based proteomics.
The ideal candidate should have an extensive knowledge of peptide/protein MS and
MS/MS analysis including SRM or MRM quatitation and experience in analytical
methods development. The ability to communicate and share technical and protein
chemistry knowledge with other researchers is crucial. Proficiency in English is
mandatory.
If you feel you are a dynamic and independent scientist who has the potential to
contribute to this exciting and challenging project, please submit your letter of interest,
C.V. and the names and addresses of three referees to laura.rubbia-brandt@unige.ch
or denis.hochstrasser@unige.ch.
Review of the applications will start the 1st of June 2011 and until the post is filed. All
enquiries will be treated in strictest confidence.
Pr Denis Hochstrasser
Biomedical Proteomics Research Group
Department of Human Protein Sciences, CMU
1 rue Michel Servet
CH-1211 Geneva 4
Switzerland