AP Biology Chapter 15 Worksheet 1. Who were Correns, VonTshermak and de Vries? 2. Give 3 parallels between Mendel’s factors and and behavior of chromosomes. 3. Who invented the chromosome theory of inheritance? 4. Describe Morgan’s work with fruit flys. 5. Why fruit flies? 6. Explain what is meant by a wild type. 7. Explain what a mutant phenotype is. 8. Explain what a sex linked gene is. 9. Explain what linked gene is. 10. Explain what is meant by genetic recombination. 11. Give 2 events that can lead to genetic recombination. 12. What is the physical basis for genetic recombination? 13. How do linked genes react during meiosis and fertilization? 14. Explain the actual result of crossing over during prophase I. 15. What accounts for the occurrence of recombinant phenotypes in Morgan’t testcross. 16. Explain what a genetic map is and what it is used for. 17. Explain how the distance between genes affects the probability of crossover occurring. 18. Explain what a linkage map is and how it is used. 19. Explain what map units are and how they are used. 20. Can genes be too far apart for crossing over to occur? Explain 21. Explain how these distant genes are mapped. 22. Explain what a cytological map is and how it is used. Part B 23. Explain the basis for the sex differences in human males and females. 24. Give 3 other sex determining systems other then XY. 25. What happens during meiosis in the XY system? 26. Are these chromosomes homologous? Explain 27. Do they undergo crossing over? 28. When do sex characteristics begin to appear in humans? 29. Explain what an SRY gene is. 30. What does this gene do? 31. What happens when an individual lacks this gene? 32. Explain what is meant by a female being a carrier. 33. Explain what is meant by hemizygous. 34. Explain how males possessing a recessive allele are different from females possessing one. 35. Explain why males are more likely to inherit sex linked recessive disorders. 36. Explain what Duchenne muscular dystrophy is and how its contracted. 37. Explain what hemophilia is and how it is contracted. 38. Explain what a Barr Body is and what it does. 39. Explain Mary Lyon’s research. Part C 1. Explain what is meant by nondisjunction and how it occurs. 2. What may be the result of this situation. 3. Explain what is meant by aneuploidy and how it occurs. 4. Explain what monosomic and trisomic cells are. 5. Explain what is meant by polyploidy and how it occurs. 6. Explain what a tetraploid is. 7. What is the potential result of polyploidy? 8. Can polyploidy be a good thing? Explain 9. Which is more damaging an extra or missing chromosome or an entire extra set? 10. Explain what a chromosome deletion is and the result. 11. Explain what a duplication is and the result. 12. Explain what an inversion is and the result. 13. Explain what a translocation is and the result. 14. How do duplications and deletions occur? 15. Explain what down’s syndrome is and how it occurs. 16. Explain what happens in Kleinefelter’s Syndrome. 17. Explain what happens in Turner’s Syndrome. 18. Explain what happens in crit du chat. 19. Explain what happens in CML. 20. Explain the difference between Prader-Willi syndrome and Angelman syndrome. 21. Explain what is meant by genomic imprinting. 22. Explain what an extra nuclear gene is. 23. Are their disorders caused from mutations of these genes? Explain