Now that you have undertaken an AS -Level test relating to Topic 2, it is now time to complete your biology profile. This will be useful in helping you to plan your approach to revision. The scale 1-5 should be interpreted as: 1 – Very disturbing 2 – Better than you feared but obviously time must be spent on this aspect 3 – Generally pleased but there are some problems to be looked at 4 – On the whole very good but some minor problems need rectifying 5 – Very pleased with this aspect, difficult to find any problems Shade in the rows to give yourself an idea of your strengths and weaknesses and add to it in different colours as you do your revision. Specification area 1 2 3 4 5 Role of concentration gradients Properties of gas exchange surfaces Structure of the unit membrane Temperature on membrane structure Osmosis, active transport, passive transport and facilitated diffusion Structure of DNA and mRNA Nature of the genetic code and genes Protein Synthesis Significance of proteins primary structure Action and specificity of enzymes Enzyme concentrations of rates of reactions DNA replication Mutations and CF Monohybrid inheritance – genotype and phenotype CF gene expression Treatment of CF Somatic and germ line therapy Moral and ethical issues of gene therapy Gel electrophoresis Genetic screening and gene probes Social, ethical, moral and cultural issues of genetic screening For all of Topic 2 Created by JAG. 31-08-02