A postdoctoral position is immediately available in the Program of Membrane Biology,
part of the Center for Systems Biology at Massachusetts General Hospital, to study
mechanisms of protein trafficking and response to injury in renal tubular epithelial cells.
Specifically, we use the water channel AQP2 as a model system to study protein
trafficking in kidney cells. We are expanding our interest to understanding the novel role
of water channels in renal tubular integrity and tubular development in kidney. Our
ultimate goal is to dissect out the mechanism of tubular dysfunction leading to kidney
injury and cystic kidney disease. We are taking comprehensive approaches and applying
multiple model systems, including in vitro 3D culture, in vitro organ culture/tissue slice
culture, isolated kidney perfusion, mouse models and zebrafish models to study various
kidney diseases.
Candidates with strong background in cellular and molecular biology and biochemistry
are preferred. Please send a CV and contact information of three references to:
Dr. Dennis Brown and/or Jenny Lu
Program in Membrane Biology
Department of Medicine
Massachusetts General Hospital
CPZN 8150
185 Cambridge St, Boston, MA 02114
Email: dbrown@partners.org, halu@partners.org