Zoo/Bot 3333 Genetics Quiz 2 September 30, 2005 For answers to the quiz, please click here: Questions 1-2 pertain to the following. In the figure to the right, gene r+ encodes a transcription factor that is mRNA required for the transcription mRNA a+ gene of the a+ gene in a certain product leads to plant; r mutants are unable to normal growth bind to the appropriate site in DNA to initiate a+ gene mRNA synthesis. The a+ gene is a growth-promoting factor, and null mutations in this gene lead to slower than normal growth, and a dwarflike phenotype. Both loci are haplosufficient. 1. True or false. One functional r+ gene will allow a plant that is homozygous for the a gene mutant to have a normal phenotype. 2. Suppose a plant that is heterozygous for the a and r mutations is allowed to selffertilize. What would be the ratio of normal to dwarf plants? a) all normal; b) 3 normal: 1 dwarf; c) 15 normal: 1 dwarf; d) 9 normal:7 dwarf; e) 13 normal; 3 dwarf. Questions 3-5 pertain to the chart on the right. In Labrador retrievers, coat color may be black, brown (chocolate) or golden. Here are some of the many possibilities resulting from the matings of dogs of different coat colors: 3: True or false. The allele responsible for golden coat color is located at the same genetic locus as the allele for brown coat color. 4. The pattern of inheritance seen in these matings indicates that the golden phenotype is an example of: a) complementary gene action; b) duplicate genes; c) dominant epistasis; d) recessive epistasis; e) dominant suppression. 5. In the cross shown in (e): a) the first parent is heterozygous for the brown allele; b) the second parent is homozygous for the golden allele; c) the second parent is heterozygous for the brown allele; d) all of the above; e) none of the above. Questions 6-8 pertain to the following. In Drosophila, Lyra (Ly) and Stubble (Sb) are dominant mutations located on chromosome 3. A recessive mutation for bright-red eyes is discovered and also shown to be located on chromosome 3. A female who was heterozygous for all three mutations was crossed to a male homozygous for the bright-red (indicated br here) mutation, with the progeny classes produced at the right: 6. The map distance from the Stubble mutation to the bright-red mutation is: a) 3.4 map units; b) 4 map units; c) 13.4 map units; d) 14 map units; e) 18 map units. Phenotype Ly Sb br Ly + br Ly + + +++ + Sb + Ly Sb + + + br + Sb br Total Number 404 75 18 422 59 4 2 16 1000 7. The Lyra locus is 19 map units from the bithorax body locus. Using the map on page 132 of your text, which gene maps closest to the bright-red mutation? a) rosy eyes; b) glass eyes; c) cardinal eyes; d) pink eyes; e) scarlet eyes. 8. True or false: For this particular data set, we see no evidence of interference between these three genes. Questions 9 and 10 pertain to the following. The following are ordered tetrad pairs from a cross between strain cd and ++: Tetrad Class 1 2 3 4 5 6 7 c+ c+ cd +d c+ cd c+ c+ cd cd c+ ++ ++ +d +d ++ ++ c+ cd cd cd +d +d ++ +d +d ++ ++ 1 17 41 1 5 3 1 9. The distance between the c locus and the centromere is approximately: a) 7.3 map units; b) 14.5 map units; c) 15.9 map units; d) 20.3 map units; e) 31.8 map units. 10. The distance between these two genes is approximately: a) 9 map units; b) 23 map units; c) these genes do not appear to be linked to one another.